Find hotels in Santa Cruz from NT$1,114

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Compare 1,851 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Property grounds
Hotel Finca Las Hortensias

Hotel Finca Las Hortensias

3.0 star property
Tepotzotlán
8.4 out of 10, Very Good, (185)
"Hortencias a fantastic place to relax on a family envornment , close to nature and outstanding sercvice"
United States
Jerry C.
The price is NT$1,855
NT$2,226 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Finca Las Hortensias
Bar (on property)
La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa

3.5 star property
Tepotzotlán
8.0 out of 10, Very Good, (40)
"na"
Mexico
Karina Ponce
La Morada Tepotzotlan Boutique & Spa
Food and drink
Verticca Hotel

Verticca Hotel

3.0 star property
Ojo de Agua
9.2 out of 10, Wonderful, (240)
"Excelente Hotel"
Mexico
juan Ricardo
Verticca Hotel
Superior Suite | Premium bedding, down comforters, in-room safe, desk
Antigua Hotel Boutique

Antigua Hotel Boutique

3.5 star property
Ciudad López Mateos
9.2 out of 10, Wonderful, (88)
"TODO EXCELENTE"
Mexico
Daniel Roberto
Antigua Hotel Boutique
Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes
Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
Downtown Mexico City
9.2 out of 10, Wonderful, (1037)
"Excellent stay!"
United States
Derek
The price is NT$2,068
NT$2,471 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Mexico Basilica by IHG
Front of property
Hot Elite | Love Hotel | Solo Adultos

Hot Elite | Love Hotel | Solo Adultos

3.0 star property
Miguel Hidalgo
7.6 out of 10, Good, (4)
"Everything turned out great. We were attended by courteous staff, the room was in perfect shape and with a great view, all in all this was a fantastic stay. "
United States
alex
The price is NT$1,367
NT$1,633 total
includes taxes & fees
Dec 8 - Dec 9
Hot Elite | Love Hotel | Solo Adultos
Free daily buffet breakfast
Fairfield Inn & Suites Mexico City Vallejo

Fairfield Inn & Suites Mexico City Vallejo

3.0 star property
Azcapotzalco
9.2 out of 10, Wonderful, (1002)
"Very Good breakfast. Loved the location."
United States
Arelis
The price is NT$2,474
NT$2,957 total
includes taxes & fees
Dec 26 - Dec 27
Fairfield Inn & Suites Mexico City Vallejo
Interior
Casa Olea

Casa Olea

2.0 star property
Downtown Mexico City
9.4 out of 10, Exceptional, (611)
"great place to stay"
United States
Violeta Pineda
The price is NT$1,393
NT$1,664 total
includes taxes & fees
Dec 23 - Dec 24
Casa Olea
Indoor pool
Fiesta Inn Ecatepec

Fiesta Inn Ecatepec

3.5 star property
Ecatepec de Morelos
8.8 out of 10, Excellent, (819)
"Excelente hotel"
Mexico
José luis
The price is NT$2,674
NT$3,209 total
includes taxes & fees
Dec 15 - Dec 16
Fiesta Inn Ecatepec
Terrace/patio
Hotel Brasilia

Hotel Brasilia

3.0 star property
Gustavo A. Madero
9.0 out of 10, Wonderful, (1004)
"Super clean hotel and the staff very pleasant and friendly."
United States
Emanuel
The price is NT$1,870
NT$2,235 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Brasilia
Business center
Downtown Treasure Place

Downtown Treasure Place

2.5 star property
Downtown Mexico City
8.8 out of 10, Excellent, (728)
"The staff was very kind, easy access, very good place to stay…"
United States
Iuren
The price is NT$935
NT$1,132 total
includes taxes & fees
Dec 8 - Dec 9
Downtown Treasure Place
Standard Double Suite | City view
UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV

4.5 star property
Miguel Hidalgo
9.2 out of 10, Wonderful, (718)
"We had a great stay. Area was safe to walk around, and hotel was near tourist attractions. "
United States
Guadalupe
The price is NT$3,157
NT$3,772 total
includes taxes & fees
Dec 8 - Dec 9
UTOPIC Polanco by ULIV
Outdoor pool
Holiday Inn Zona Centro by IHG

Holiday Inn Zona Centro by IHG

3.5 star property
Downtown Mexico City
9.2 out of 10, Wonderful, (1000)
"Clean, quiet, staff was super great! We shall be back! "
United States
Gabino
The price is NT$3,050
NT$3,644 total
includes taxes & fees
Dec 27 - Dec 28
Holiday Inn Zona Centro by IHG
Luxury Apartment, Balcony, City View | Dining room
Capitalia Antara Polanco

Capitalia Antara Polanco

4.5 star property
Polanco
9.2 out of 10, Wonderful, (165)
"Super smooth. Great rooms!!"
United States
Javier
Capitalia Antara Polanco
Bar (on property)
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 star property
Zumpango
9.4 out of 10, Exceptional, (944)
"Great service clean rooms"
United States
Alberto
The price is NT$3,421
NT$4,105 total
includes taxes & fees
Jan 6 - 2026/1/7
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Garden
Krystal Satélite María Bárbara

Krystal Satélite María Bárbara

3.5 star property
Tlalnepantla de Baz
8.4 out of 10, Very Good, (1342)
"Wonderful place to stay!"
Canada
Antonio
The price is NT$2,166
NT$2,599 total
includes taxes & fees
Jan 4 - 2026/1/5
Krystal Satélite María Bárbara
3 restaurants, breakfast, lunch, dinner served; Latin American cuisine
Hyatt Regency Mexico City

Hyatt Regency Mexico City

5.0 star property
Polanco
9.4 out of 10, Exceptional, (1323)
"Beautiful location hotel staff "
United States
Rajat
The price is NT$7,302
NT$8,726 total
includes taxes & fees
Jan 1 - 2026/1/2
Hyatt Regency Mexico City
Lobby lounge
City Express by Marriott Ciudad de México La Villa

City Express by Marriott Ciudad de México La Villa

3.0 star property
Downtown Mexico City
8.8 out of 10, Excellent, (1005)
"The staff very courteous, the room very clean "
United States
Yolanda
The price is NT$2,285
NT$2,730 total
includes taxes & fees
Jan 5 - 2026/1/6
City Express by Marriott Ciudad de México La Villa
Terrace/patio
Fiesta Americana México Satélite

Fiesta Americana México Satélite

4.5 star property
Tlalnepantla de Baz
9.4 out of 10, Exceptional, (741)
"nice hotel and great location "
United States
karen
The price is NT$2,841
NT$3,409 total
includes taxes & fees
Dec 16 - Dec 17
Fiesta Americana México Satélite
Lobby
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham

3.5 star property
Cuautitlan Izcalli
9.2 out of 10, Wonderful, (583)
"Great Team"
United States
Fangchu
The price is NT$1,766
NT$2,119 total
includes taxes & fees
Dec 14 - Dec 15
Hotel MX mas cuautitlan Izcalli, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

10/10 Excellent
"Clean room"
Hilarion 1-night trip
Posted 3 days ago
Holiday Inn Express Mexico Basilica by IHG

More cheap stays in Santa Cruz

Hotel Ancona - Adults Only

Hotel Ancona - Adults Only

226 Calle Eligio Ancona Mexico City CDMX
Get rates
8/10 Very Good! (336 reviews)

Frequently asked questions

Where is the best place for a stay in Santa Cruz?
La Morada Tepotzotlan Boutique & Spa is a favorite with Expedia customers. This hotel offers a full-service spa and a restaurant. Hotel Finca Las Hortensias is another favorite option for your stay based on traveler reviews. See all available top hotels, or vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about changing or cancelling your trip to Santa Cruz, head over to our customer service page.
What is staying in Santa Cruz like?
Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. In Santa Cruz, there are 2 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Hacienda La Concepcion, National Museum of the Viceroyalty, and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually April and May with an average temp of 64°F, while the coldest months are January and December with an average of 57°F. The rainiest months in Santa Cruz are August, July, September, and June, with each month seeing an average of 7 inches of rainfall.

Explore a world of travel with Expedia