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Compare 1,789 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Fiesta Inn Cuautitlan
Relax by the pool surrounded by lush greenery and palm trees.

Fiesta Inn Cuautitlan

3.5 star property
8.6 out of 10, Excellent, (347)
"The hotel is clean, and the staff are pleasant and helpful"
The price is NT$2,781
NT$3,337 total
includes taxes & fees
Jul 18 - Jul 19
Fiesta Inn Cuautitlan
Hotel Tres Colonias - Adults Only
Experience the grandeur of our multi-level atrium, featuring a high ceiling and central open area surrounded by potted plants.

Hotel Tres Colonias - Adults Only

2.5 star property
8.0 out of 10, Very Good, (228)
"Great location!"
The price is NT$615
NT$735 total
includes taxes & fees
Jul 23 - Jul 24
Hotel Tres Colonias - Adults Only
Hotel Piet
Park your vehicle in the designated area, with clear signage guiding you through the Zona de Maniobras.

Hotel Piet

2.0 star property
7.4 out of 10, Good, (113)
"Nice hotel staff."
Hotel Piet
Hotel Finca Las Hortensias
Stroll through a serene garden surrounded by lush greenery and historic architecture.

Hotel Finca Las Hortensias

3.0 star property
8.2 out of 10, Very Good, (177)
"Front desk service was excellent, the food was delicious and the service from Saul was wonderful. "
The price is NT$1,686
NT$2,024 total
includes taxes & fees
Jul 23 - Jul 24
Hotel Finca Las Hortensias
Downtown Treasure Place
Contemporary space with a high ceiling, seating area, and staircase.

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (615)
"Very nice place to stay for a quick trip to Mexico City Staff very friendly "
Downtown Treasure Place
Verticca Hotel
Enjoy a convenient and enjoyable meal experience in our well-equipped buffet area, featuring a variety of food options and ample storage.

Verticca Hotel

3.0 star property
9.4 out of 10, Exceptional, (170)
"Great place to stay! "
Verticca Hotel
Mala Vecindad Centro Historico
Relax by the pool and enjoy the city views.

Mala Vecindad Centro Historico

3.0 star property
8.8 out of 10, Excellent, (54)
"Excelente hotel"
Mala Vecindad Centro Historico
Mala Vecindad Beer Hotel
Meet and collaborate in this well-equipped meeting room with a polished table and comfortable seating.

Mala Vecindad Beer Hotel

3.0 star property
8.0 out of 10, Very Good, (191)
"A BEAUTIFUL hotel overall. Would repeat the stay."
Mala Vecindad Beer Hotel
Hotel Mina
Stroll through the airy corridor with a skylight above, lined with doors to various areas and a potted plant adding a touch of greenery.

Hotel Mina

2.5 star property
7.6 out of 10, Good, (415)
"grN HOTEL GRAN PERSONAL"
The price is NT$831
NT$994 total
includes taxes & fees
Aug 14 - Aug 15
Hotel Mina
RHM Spaces - Santa Maria
Cozy retreat with a single bed, desk, and window overlooking trees.

RHM Spaces - Santa Maria

2.0 star property
6.8 out of 10, (35)
"Convenient place for 1-2 person stay"
The price is NT$368
NT$440 total
includes taxes & fees
Jul 16 - Jul 17
RHM Spaces - Santa Maria
Capital O Df Inn, Ciudad de Mexico
Relax in this inviting space with a glass roof, patterned tiles, and comfortable seating areas.

Capital O Df Inn, Ciudad de Mexico

3.0 star property
8.0 out of 10, Very Good, (343)
"A really good hotel to stay at if you need a centric place to stay. It is in the red zone district and it does not have an elevator, but the rooms are comfortable and the staff is very kind."
The price is NT$1,083
NT$1,439 total
includes taxes & fees
Jul 28 - Jul 29
Capital O Df Inn, Ciudad de Mexico
Gran Hotel Panorama
Welcome to our lobby, featuring a unique cylindrical pillar, a glass-enclosed plant, and a patterned design on the walls.

Gran Hotel Panorama

3.0 star property
8.4 out of 10, Very Good, (941)
"Friendly staff "
The price is NT$602
NT$719 total
includes taxes & fees
Jul 21 - Jul 22
Gran Hotel Panorama
Hotel Verona
Relax in a stylish room with a large bed, bedside table, and window offering a view of the outside.

Hotel Verona

2.5 star property
7.6 out of 10, Good, (201)
"Excelente "
The price is NT$842
NT$1,051 total
includes taxes & fees
Jul 21 - Jul 22
Hotel Verona
Hotel Ancona - Adults Only
Staircase with a red handrail leads to an upper floor, flanked by potted plants and a white-framed window.

Hotel Ancona - Adults Only

2.5 star property
8.2 out of 10, Very Good, (302)
"Excelente"
Hotel Ancona - Adults Only
Collection O Hotel Lavanda Anzures
Enter a grand space with a high archway, patterned floor, and elegant artwork.

Collection O Hotel Lavanda Anzures

2.0 star property
8.2 out of 10, Very Good, (337)
"We enjoyed our stay"
The price is NT$879
NT$1,212 total
includes taxes & fees
Jul 27 - Jul 28
Collection O Hotel Lavanda Anzures
Hotel Dharma
Stroll through the serene garden, surrounded by lush potted plants and trees.

Hotel Dharma

3.0 star property
8.2 out of 10, Very Good, (407)
"I liked the cleanliness. No a/c, some noises not appr "
Hotel Dharma
Hotel SR92 Only Adults
A standard toilet is situated in a bathroom with a tiled floor and walls.

Hotel SR92 Only Adults

2.5 star property
7.2 out of 10, Good, (242)
"This is an hourly hotel if you know what I mean but it's very affordable and a short walk to the main boulevard. Staff is constantly cleaning and super friendly."
Hotel SR92 Only Adults
Fiesta Inn Tlalnepantla
Enjoy a diverse selection of international cuisine at our buffet, featuring stations for pasta, salads, and more.

Fiesta Inn Tlalnepantla

3.5 star property
8.8 out of 10, Excellent, (483)
"I loved the easy check in"
The price is NT$1,922
NT$2,306 total
includes taxes & fees
Jul 18 - Jul 19
Fiesta Inn Tlalnepantla
Hotel Santa María
Stylish M Hotel features a modern architectural design with a textured facade and multiple levels.

Hotel Santa María

2.5 star property
7.8 out of 10, Good, (131)
"Hotel is in a residential area and more of a motel. Cleanliness was extremely high and the staff were friendly and helpful There's no restaurant on site but within easy walking distance are a large mall, lots of cafes & shopsplus bus & metro stations For a budget hotel it does its job perfectly just dont expect 3 or 4 star standards Only dowsides for me are wifi quality & no cupboard / hanging space for clothes"
The price is NT$1,139
NT$1,361 total
includes taxes & fees
Jul 25 - Jul 26
Hotel Santa María
Residence L´ Heritage Royal Colonial by BlueBay
Experience the airy, open design of this multi-level atrium with ornate railings and a stunning glass staircase.

Residence L´ Heritage Royal Colonial by BlueBay

3.0 star property
7.8 out of 10, Good, (226)
"The staff and location are very good. It a good hotel for stay one or more night. Only weak point about air conditioner, there is non any type of it"
The price is NT$2,116
NT$2,529 total
includes taxes & fees
Jul 16 - Jul 17
Residence L´ Heritage Royal Colonial by BlueBay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Venture to Hacienda La Concepcion and Temple of San Francisco Javier—just two of the sights around Santa Cruz.

See all hotels in Santa Cruz

Frequently asked questions

Where is the best place for a stay in Santa Cruz?

Located 18.9 mi (30.4 km) from the heart of Santa Cruz, InterContinental Presidente Mexico City by IHG is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Casa Olea and Hyatt Regency Mexico City. See all available top hotels, or vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about changing or cancelling your trip to Santa Cruz, head over to our customer service page.

What are some accommodations with pools in Santa Cruz?

Hotel Finca Las Hortensias: Features free parking, an outdoor pool, and free WiFi. Hyatt Regency Mexico City and Fiesta Americana México Toreo are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Hotel Finca Las Hortensias is a top spa hotel featuring a restaurant and a bar.

What is staying in Santa Cruz like?

Those traveling to Santa Cruz are sure to enjoy the sights to see and things to do. There are 1788 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Places to visit in the wider area include Hacienda La Concepcion, Temple of San Francisco Javier, and San Marcos Power Center. You'll also find Xochitla Ecological Park and Arcos del Sitio in the area. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually April and May with an average temp of 64°F, while the coldest months are January and December with an average of 57°F. The rainiest months in Santa Cruz are August, July, September, and June, with each month seeing an average of 7 inches of rainfall.