Santa Ana

Antigua Guatemala

Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.
Iglesia de Nuestra Señora de Santa Ana, aldea Santa Ana en Antigua Guatemala.

Popular places to visit

Antigua, Guatemala, volcano

Central Park

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Central Park
Panoramic inside the ruins of Antigua's Cathedral, one of the many buildings that collapsed after the earthquake that destroyed the city in 1773.

Antigua Guatemala Cathedral

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours.

Antigua Guatemala Cathedral
Recent trip to Antigua, Guatemala.

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Santa Catalina Arch
Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this family-friendly area, or enjoy its local tours.

Antigua Market
A one of a kind facade

La Merced Church

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

La Merced Church
Cerro de la Cruz Antigua Guatemala

Cerro de La Cruz

You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours.

Cerro de La Cruz

Santa Ana Hotel Deals

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
The price is NT$2,064 per night from Feb 17 to Feb 18
NT$2,064
NT$2,518 total
Feb 17 - Feb 18
includes taxes & fees
Stay at this hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...
9/10 Wonderful! (48 reviews)
Me encantó el lugar ! Es espectacular un jardín lindísimo, el desayuno excelente y la atención de igual manera definitivamente volvería

Reviewed on 2026/1/19

Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
The price is NT$2,783 per night from Mar 2 to Mar 3
NT$2,783
NT$3,395 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (3,195 reviews)
Clean, spacious

Reviewed on 2026/2/12

Barceló Guatemala City
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
The price is NT$2,817 per night from Mar 15 to Mar 16
NT$2,817
NT$3,437 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,689 reviews)
Excellent staff

Reviewed on 2026/2/5

Wyndham Garden Guatemala City
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is NT$8,363 per night from Feb 25 to Feb 26
NT$8,363
NT$10,586 total
Feb 25 - Feb 26
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,042 reviews)
Food amazing specially the breakfast!

Reviewed on 2026/2/10

Hotel Museo Spa Casa Santo Domingo
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is NT$5,973 per night from Feb 23 to Feb 24
NT$5,973
NT$8,074 total
Feb 23 - Feb 24
includes taxes & fees
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,000 reviews)
Good

Reviewed on 2026/2/8

Hotel Camino Real Antigua
Holiday Inn Guatemala City by IHG

Holiday Inn Guatemala City by IHG

3.5 out of 5
1a Avenida 13-22 Zona 10 Guatemala City Guatemala
The price is NT$3,364 per night from Mar 8 to Mar 9
NT$3,364
NT$4,104 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Guatemala City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9/10 Wonderful! (1,001 reviews)
Yes

Reviewed on 2026/2/8

Holiday Inn Guatemala City by IHG
See all 1,189 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Ana

Cross and Volcan de Agua View From Cerro de la Cruz, Antigua, Sacatepequez Department, Guatemala

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Barrio de La Concepción
Vue du volcan de Fuego

Historic Center

While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

Historic Center

Santa Ana