Santa Ana Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$5,067 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Santa Ana Hotel Deals

Casa Buho B&B

Casa Buho B&B

3 out of 5
77 Calle del Agua Antigua Guatemala Guatemala
Fully refundableReserve now, pay when you stay
The price is NT$2,099 per night from Apr 21 to Apr 22
NT$2,099
NT$2,560 total
Apr 21 - Apr 22
includes taxes & fees
9.2/10 Wonderful! (51 reviews)
Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning

Reviewed on 2026/2/28

Casa Buho B&B
Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is NT$3,671 per night from Apr 26 to Apr 27
NT$3,671
NT$4,478 total
Apr 26 - Apr 27
includes taxes & fees
9.2/10 Wonderful! (3,277 reviews)
Clean, quiet, respectful and everyone is helpful. I was surprised to see how many languages are spoken to make sure you are well informed about all the services offered. Always smelling great, close to so many useful spots (stores, restaurants) 9.5/10

Reviewed on 2026/4/3

Barceló Guatemala City
Wyndham Garden Guatemala City

Wyndham Garden Guatemala City

4 out of 5
1a Avenida 12-46 Zona 10 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
The price is NT$3,455 per night from May 3 to May 4
NT$3,455
NT$4,215 total
May 3 - May 4
includes taxes & fees
9.2/10 Wonderful! (1,742 reviews)
Phone did not work in the room

Reviewed on 2026/4/3

Wyndham Garden Guatemala City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you'd like to snag a cheap Santa Ana vacation package, consider visiting in June, September and October. You'll usually find better prices on accommodations and flights during these months — perfect for a budget-friendly break.
How many days is enough for Santa Ana?
Generally, a handful of days is enough to tick off the main attractions during your Santa Ana vacation. However, if you'd like to have time to relax or go on day trips, consider extending your itinerary.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customize your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa Ana?
If you're considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you'd like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you're more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodations and airfare: After you've nailed down your trip dates and duration, book the perfect Santa Ana vacation package for you.

Discover the most popular places to visit in Santa Ana

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.