Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
This resort is the place to go on the happening Isla Flamenco. Inside you'll find a Duty Free store, a pick & mix candy buffet called Sweet Day, and several restaurants. Not to mention a stunning view of the Flamenco Marina & the Panama City skyline. Did you know that Fort Amador was actually a US army base, built to protect the Panama Canal? When the US pulled out

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

4.5/5(783 reviews)

Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Calle 50

You can find out about the history of Panama City with a trip to Calle 50. Discover the area's shops, or seek out its local tours.

Calle 50

Santa Ana Hotel Deals

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3.5-star condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.2/10 Wonderful! (48 reviews)
"Great stay, would recommend."

Reviewed on 2025/9/4

Get rates
Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is NT$3,629 per night from Nov 5 to Nov 6
NT$3,629
NT$3,992 total
Nov 5 - Nov 6
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,358 reviews)
"Lovely"

Reviewed on 2025/10/9

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is NT$3,278 per night from Nov 1 to Nov 2
NT$3,278
NT$3,606 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,242 reviews)
"always take a cab..easy and no wait"

Reviewed on 2025/10/13

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is NT$8,318 per night from Oct 27 to Oct 28
NT$8,318
NT$8,318 total
Oct 27 - Oct 28
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,005 reviews)
"Very nice"

Reviewed on 2025/10/6

Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is NT$3,873 per night from Nov 1 to Nov 2
NT$3,873
NT$4,261 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (964 reviews)
"Centrally located and friendly staff"

Reviewed on 2025/10/10

Sheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is NT$3,946 per night from Nov 1 to Nov 2
NT$3,946
NT$4,340 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,120 reviews)
"Best"

Reviewed on 2025/10/10

Megapolis Hotel Panamá
See all 1,527 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Ana

My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Casco Viejo
My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Ancon Hill.

El Chorrillo
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Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.

Balboa
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Marbella

5/5(2 area reviews)

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

Santa Ana