Santa Ana
Panama City



Popular places to visit

Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Amador Causeway
You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Uruguay Street
During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.

Calle 50
You can find out about the history of Panama City with a trip to Calle 50. Discover the area's casinos, or seek out its local tours.
Santa Ana Hotel Deals

Casco View Apartments
The space was very nice.
Reviewed on 2026/2/1

Hotel Riu Plaza Panama
Everything was great, the food, room amenities and location
Reviewed on 2026/2/8

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
The first rooms on the first floor 141 & 139 was horrible. But the room was change to the 8 floor 801&806 the rooms was prefect nice an clean i loved them rooms. Staff was prefect even though i was mad at them for putting us in the first rooms they still was professional.
Reviewed on 2026/2/10

Crowne Plaza Panama Airport by IHG
We stayed here 2 nights at separate occasions during our trip. One of the nights we got a room that seemed older. Nice common area with restaurant and very close to airport.
Reviewed on 2026/2/7

W Panama
Room
Reviewed on 2026/2/10

Waymore Hotel Spa & Casino
Staff was friendly, room was clean and for the price, it was worth it.
Reviewed on 2026/2/12
Other neighborhoods around Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

El Chorrillo
While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Flag of Cerro Ancón.

Calidonia
You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Balboa
The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Flag of Cerro Ancón, a few notable attractions nearby.

Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Multicentro Panama or Avenida Balboa.
