Find Business Hotels in San Marco, FL

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Check availability on San Marco Business Hotels

Our top choices for San Marco business-friendly hotels

Exterior
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank
3.0 star property
San Marco
8.6 out of 10, Excellent, (761)
"Clean hot tub and overall nice and up kept hotel"
United States
Cameron
The price is NT$3,467
NT$3,936 total
includes taxes & fees
Dec 19 - Dec 20
Homewood Suites by Hilton Jacksonville Downtown-Southbank
Restaurant
Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
Northside
9.0 out of 10, Wonderful, (98)
"Will stay here again "
United States
Jose
The price is NT$2,245
NT$2,548 total
includes taxes & fees
Dec 22 - Dec 23
Extended Stay America Premier Suites - Jacksonville - Airport
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside
9.2 out of 10, Wonderful, (1000)
"Good location, friendly staff, clean "
United States
john
The price is NT$3,717
NT$4,219 total
includes taxes & fees
Dec 13 - Dec 14
Hyatt Place Jacksonville / St. Johns Town Center
Exterior
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville
9.0 out of 10, Wonderful, (1381)
"Nice stay"
United States
April
The price is NT$4,490
NT$5,147 total
includes taxes & fees
Dec 19 - Dec 20
Hyatt Regency Jacksonville
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
Palm Valley
9.0 out of 10, Wonderful, (1012)
"We have stayed here in the past,excellent location. We especially enjoyed our food from Mulligan's..our waitress was exceptional. "
United States
Robert
The price is NT$3,604
NT$4,018 total
includes taxes & fees
Jan 4 - 2026/1/5
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Restaurant
TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg

TownePlace Suites by Marriott Middleburg
2.5 star property
Middleburg
10.0 out of 10, Exceptional, (23)
"Friendly staff Clean room Nice workout room Great breakfast"
United States
Robin
The price is NT$3,868
NT$4,352 total
includes taxes & fees
Dec 21 - Dec 22
TownePlace Suites by Marriott Middleburg
Desk, laptop workspace, blackout drapes, iron/ironing board
Airport Motor Inn

Airport Motor Inn

Airport Motor Inn
2.5 star property
Northside
8.6 out of 10, Excellent, (40)
"Very clean and quiet."
United States
Sylvia
The price is NT$1,992
NT$2,261 total
includes taxes & fees
Dec 23 - Dec 24
Airport Motor Inn
Lobby
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Jacksonville Beach
9.0 out of 10, Wonderful, (3426)
"Excellent location & property "
United States
Doris
The price is NT$4,462
NT$5,065 total
includes taxes & fees
Dec 14 - Dec 15
Margaritaville Jacksonville Beach
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
Jacksonville Beach
9.0 out of 10, Wonderful, (1001)
"Good location for exploring Ponte Vedra and Jacksonville Beach areas."
United States
Julianne
The price is NT$3,467
NT$3,936 total
includes taxes & fees
Dec 19 - Dec 20
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Southside
9.2 out of 10, Wonderful, (1001)
"Good hotel!"
United States
Charlie
The price is NT$2,783
NT$3,159 total
includes taxes & fees
Dec 28 - Dec 29
Sheraton Jacksonville Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Marco Hotel Reviews

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

10/10 Excellent
"Very nice venue, with a beautiful and spacious suite!"
Stephen 1-night trip
Posted 2 days ago
Hyatt Place Jacksonville Airport

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Frequently asked questions

Why book your business-friendly hotel in San Marco with Expedia?
With useful amenities like conference rooms, laundry facilities and on-site restaurants, our business-friendly properties come with everything you'll need to settle your important deal — and then kick back! Enter your travel destination and preferred dates and we'll help you with the rest.
How can I find cheap business-friendly hotels in San Marco?
When work takes you on the road in San Marco, our "business friendly" filter will help you find the perfect hotel. From free WiFi and included breakfast to concierge services and conference spaces, they come with the amenities you need to get the job done. Another handy tip? Narrow your search by your preferred star rating and budget to view the most affordable accommodations.