Search Hotels in Santa Cruz

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top cities in Santa Cruz

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (428 reviews)
"I love how nice and helpful staff was."
United States
Lizzie
The price is NT$5,279
NT$5,279 total
Nov 17 - Nov 18
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

2. Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
Casa Por Temporadas

3. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (261 reviews)
"Amazing hotel"
United States
Deivis
The price is NT$3,781
NT$3,781 total
Nov 28 - Nov 29
Marriott Santa Cruz de la Sierra Hotel

4. Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (457 reviews)
"The food is excellent quality and delicious! Friendly staff"
United States
Wendy
The price is NT$3,870
NT$3,870 total
Nov 14 - Nov 15
Camino Real Hotel

5. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (419 reviews)
"The room and the bed, towels were very clean.The breakfast was very complete and very good."
Canada
Andre Leo
The price is NT$3,460
NT$3,460 total
Nov 14 - Nov 15
Sun Hotel

6. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Equipetrol
9.4 out of 10, Exceptional, (159 reviews)
"Good location and value for money."
United States
Hui Hua
The price is NT$1,384
NT$1,384 total
Dec 4 - Dec 5
Ibis Santa Cruz DE LA Sierra

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (295 reviews)
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
United States
Scott
The price is NT$2,419
NT$2,419 total
Nov 15 - Nov 16
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

8. Hotel Las Américas

Hotel Las Américas
3.0 star property
Centro Histórico
7.8 out of 10, Good, (36 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is NT$858
NT$858 total
Nov 14 - Nov 15
Hotel Las Américas

9. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (121 reviews)
"great place to stay!"
United States
Luisa
The price is NT$1,512
NT$1,512 total
Nov 14 - Nov 15
Premium Suites Deluxe Aparthotel Equipetrol

10. Hotel Cortez

Hotel Cortez
3.5 star property
Equipetrol
9.4 out of 10, Exceptional, (163 reviews)
"Great place to stay, with restaurants and stores nearby."
United States
Rigoberto
The price is NT$4,259
NT$4,259 total
Nov 15 - Nov 16
Hotel Cortez

11. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (134 reviews)
"Love staying there…. Very clean and staff always willing to assist."
United States
Carol
The price is NT$4,358
NT$4,358 total
Dec 4 - Dec 5
Novotel Santa Cruz De La Sierra

12. Lido Hotel

Lido Hotel
3.0 star property
Centro Histórico
9.2 out of 10, Wonderful, (58 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is NT$836
NT$836 total
Nov 14 - Nov 15
Lido Hotel

13. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (107 reviews)
"Great location."
United States
Ruben
The price is NT$887
NT$887 total
Nov 14 - Nov 15
Apart Hotel Premium Suites Santa Cruz

14. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (61 reviews)
"Clean room, good staff,"
United States
Neftali
The price is NT$1,442
NT$1,442 total
Nov 15 - Nov 16
HOTEL OSHO

15. Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (81 reviews)
"clean close to restaurants friendly staff shop nearby overall excellent place to stay"
United States
Luis
The price is NT$1,553
NT$1,553 total
Nov 14 - Nov 15
Chairú Eco Hotel

16. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (112 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is NT$838
NT$838 total
Dec 12 - Dec 13
Hotel G

17. Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (103 reviews)
"Great location, nice and quiet neighborhood."
United States
ALEJANDRO
The price is NT$1,568
NT$1,568 total
Nov 28 - Nov 29
Delfines Collection Hotel By Mercure

18. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Equipetrol
9.2 out of 10, Wonderful, (186 reviews)
"Beautiful hotel. Spacious room. House cleaning came every day. We got new towels every day and toiletries in the bathroom were refilled every day. Staff were friendly. View from the breakfast room was beautiful. Location of the hotel is good."
Canada
Kristina
The price is NT$2,277
NT$2,277 total
Nov 17 - Nov 18
TRYP by Wyndham Santa Cruz

19. Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (3 reviews)
"A localização é ótima, a hospedagem se vc tiver sozinho tambem é ótima agora duas pessoas ja ficou apertado. O quarto é apertado os outros locais são ótimos"
Brazil
Paola
The price is NT$745
NT$745 total
Nov 15 - Nov 16
Mirador del Cielo

20. Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Equipetrol
9.4 out of 10, Exceptional, (50 reviews)
"Beautiful place, wonderful artwork"
United States
Elizabeth
The price is NT$3,551
NT$3,551 total
Nov 30 - Dec 1
Alfonsina Hotel Boutique by Inboccaluppo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.
Showing deals for:Nov 20 - Nov 22
Showing deals for:Dec 13 - Dec 14

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Top reasons to visit Santa Cruz

  • Vibrant Culture: Experience the rich cultural heritage of Santa Cruz through its local markets, eateries, and bustling downtown area.
  • Outdoor Adventures: Enjoy outdoor activities and explore nearby national parks that showcase the region's natural beauty.
  • Family-Friendly Activities: Visit water parks and music venues, making it a great destination for family vacations.
  • Welcoming Atmosphere: Experience the sunny weather and friendly locals that contribute to Santa Cruz's charm.
  • Diverse Accommodations: Find a range of lodging options, from luxury hotels to budget-friendly hostels, catering to every traveler.

Find great hotels in Santa Cruz

Discover a range of hotel accommodations in Santa Cruz, Bolivia, designed to cater to every type of traveler. Whether you're seeking a business-friendly environment, a family getaway, or a pet-friendly experience, you'll find the perfect option here. From luxury hotels to budget-friendly hostels, explore the best Santa Cruz has to offer, along with insightful hotel reviews to help you make the right choice for your stay.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: This 3.5-star hotel offers a serene environment infused with family-friendly amenities and a spa-themed atmosphere. Located in the vibrant city of Santa Cruz, Los Tajibos stands out with its emphasis on relaxation and wellness. Guests can indulge in a variety of spa services, including massages and aromatherapy treatments, while the accessible pool provides a refreshing escape. Families will appreciate the thoughtful children’s amenities, such as a First Aid Kit, ensuring peace of mind during their stay. The hotel’s combination of comfort and tranquility makes it a great choice for those seeking both adventure and relaxation.
  • Marriott Santa Cruz de la Sierra Hotel: A luxurious 5-star property, the Marriott offers a sophisticated atmosphere perfect for family vacations and business travelers alike. Located in Santa Cruz, this hotel boasts a range of amenities, including an outdoor pool with umbrellas for shade and an onsite spa that provides daily treatments and massages. Families can take advantage of the complimentary cribs, making it easy for those traveling with young children. The Marriott’s blend of upscale accommodations and professional services ensures a comfortable and convenient stay for both leisure and business guests.
  • Camino Real Hotel: This 4-star hotel combines elegance with family-oriented amenities in the heart of Santa Cruz. With a guest rating of 9.0, Camino Real is recognized for its welcoming environment and spa services, including a sauna and hot tub. The hotel provides various children’s amenities, such as babysitting services and a shared playground, catering to families traveling with children. The indoor pool and swim-up bar offer a refreshing retreat after a day of exploration. Camino Real is an excellent choice for travelers seeking a blend of relaxation and family-friendly features in a stylish setting.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, offers a vibrant blend of cultural and urban experiences, perfect for family vacations. Explore the bustling downtown area, where local markets and eateries showcase the region's rich heritage. Just a short trip away, you can enjoy the scenic beauty of nearby tropical regions. With sunny weather and a welcoming atmosphere, Santa Cruz invites you to immerse yourself in its unique charm and discover the best of Bolivian culture.

  • Santa Cruz: As the largest city in Bolivia, Santa Cruz offers a vibrant blend of urban life and cultural experiences. Nestled in the eastern part of the country, it serves as a gateway for travelers seeking family-friendly activities, shopping, and cultural exploration. The city’s attractions include the picturesque piazza square, the lush botanical garden, and the stunning cathedral. Visitors can enjoy an array of shopping malls and resorts, making it an ideal spot for a city-themed vacation. With a steady influx of tourists year-round, the best times to visit are in January, July, and September.
  • Samaipata: Located approximately 120 kilometers from Santa Cruz, Samaipata is a picturesque town known for its stunning natural scenery and outdoor adventures. This charming destination attracts travelers looking for hiking trails and archaeological sites, including the fascinating pre-Columbian ruins. With its mild climate and breathtaking landscapes, Samaipata is perfect for those who enjoy outdoor activities and cultural immersion. The peak tourist seasons are in January, July, and September, making it a lively spot for adventure seekers and nature lovers.
  • Montero: Situated just a short drive from Santa Cruz, Montero is a city rich in culture and local charm. Known for its friendly atmosphere, visitors can explore the town’s central piazza square and engage with the vibrant community. Although it may not be as bustling as Santa Cruz, Montero provides a unique glimpse into Bolivian life and culture. The best times to visit are in January and during the months of September to October, making it an ideal stop for those interested in city-themed exploration.

Things to do in Santa Cruz

Shopping

Visit Ventura Mall in Santa Cruz for a mix of local and international brands, dining options, and entertainment. For a more traditional shopping experience, explore the Mercado Los Pozos, where you can find handmade crafts and authentic Bolivian souvenirs to take home.

Recreation

At La Casa de la Salud, indulge in holistic therapies that combine traditional practices with modern wellness techniques. Enjoy rejuvenating massages and yoga sessions in a tranquil setting, promoting relaxation and mindfulness. Nearby, the Parque Urbano is ideal for leisurely walks amid lush greenery, enhancing your connection with nature.

Adventure

The Amboro National Park offers thrilling hikes through diverse ecosystems, where you can spot unique wildlife and breathtaking landscapes. For adrenaline seekers, the Lomas de Arena Regional Park provides opportunities for sandboarding and quad biking across stunning dunes, a truly exhilarating experience in Bolivia's natural beauty.

Nightlife

Santa Cruz's nightlife comes alive with vibrant bars like Café del Mundo, where you can sip craft cocktails. For dancing, check out La Mansion, known for its lively atmosphere. Enjoy live music at Casa de la Cultura or unwind at the laid-back El Gato, perfect for mingling with locals.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money on your trip to Santa Cruz, Bolivia, consider visiting during January, June, or August for lower prices, while avoiding the pricier months of March, September, and December. Saturdays are the cheapest days to stay, while Tuesdays tend to be the most expensive. Utilize Expedia’s search tool to filter for budget-friendly hotel options and consider booking a package deal that combines your hotel, flights, and activities for additional savings. Look out for hotel deals and compare room rates for the best offers.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are January, June and August, where the prices are slightly lower. This is in comparison to March, September and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your options based on your budget, desired location, and preferred hotel category. To find the best prices and offers, simply arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your hotel stay in Santa Cruz with your flights and activities through an Expedia package deal.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, is perfect for culture-themed and family vacations, offering a variety of attractions such as national parks, cathedrals, and squares. Visitors can enjoy outdoor adventures and cultural experiences, making it an ideal destination. Don't miss the Santa Cruz Wharf and consider exploring Santa Cruz de Tenerife as well. With its vibrant atmosphere, there's always something exciting to discover in this charming city.

  • Plaza 24 de Septiembre: This lively square is the heart of Santa Cruz, surrounded by vibrant local culture and bustling activity. It serves as a meeting point for locals and tourists alike, with charming cafes and shops nearby. The square’s beautiful gardens and historical monuments create a picturesque atmosphere, making it an ideal spot for relaxation and people-watching.
  • Amboró National Park: A paradise for nature lovers, this national park boasts diverse ecosystems and breathtaking landscapes. Visitors can explore lush forests, stunning waterfalls, and unique wildlife. Hiking and guided tours offer an adventurous way to immerse yourself in the park's natural beauty.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, this cathedral features intricate details and an impressive interior. Its serene ambiance invites contemplation, making it a significant cultural landmark in Santa Cruz, ideal for those interested in history and architecture.

Best time to go to Santa Cruz

The best time to visit Santa Cruz is dependent on what kind of holiday you are seeking. October is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. June is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

Calendar MonthTemperaturePrecipitationCloudinessOccupancyPricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly LowAverage
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
April74.5°F (23.6°C)Light RainMostly SunnyAverageSlightly High
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageSlightly Low
August72.9°F (22.7°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageSlightly High
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowAverage

The nearest major airports for your trip to Santa Cruz

Flying into Santa Cruz, Bolivia, is convenient with several airport options. Viru Viru International Airport (VVI) is located 16km from the city center and serves as the main gateway, with nearby hotels such as the 5-star Marriott Santa Cruz de la Sierra and Novotel Santa Cruz De La Sierra, both within 18km. The Hampton by Hilton Santa Cruz/Equipetrol offers 24-hour airport shuttle services for easy transportation. Chimore Airport (CCA) and Alcantarí International Airport (SRE) are also accessible but situated 229km and 264km away, respectively, making VVI the most practical choice for travelers.

Frequently Asked Questions

How much do hotels in Santa Cruz cost?

The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from NT$835 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.

When is the best time to go to Santa Cruz?

If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.

Are there any luxury hotels in Santa Cruz?

Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.

What are the top all-inclusive hotels in Santa Cruz?

If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.

How can I find cheap hotels in Santa Cruz?

Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from NT$835 per night.

What are the best hotels in Santa Cruz for families?

Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.

Why should I book my Santa Cruz hotel with Expedia?

Book your Santa Cruz hotel with Expedia and enjoy a world of options at unbeatable prices. Use our search filters to help you find exactly what you want, whether that's a 5-star escape or something a little more unique, like a houseboat, log cabin or villa! Join Expedia Rewards and you'll save 10% or more on over 100,000 hotels worldwide when you're signed in. Collect points on eligible bookings, which you can use to save on your next epic adventure. Plus, many of our hotels come with flexible cancellation policies, so you can rest easy if your plans happen to change.

Explore a world of travel with Expedia