Top 10 Hotels in O Brien, FL from NT$2,056 - Competitive Prices

A calm river with clear water, surrounded by dense trees and rocky banks.

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Pool

Family friendly

Waterpark

Condo

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Our top choices for O Brien hotels

Premium bedding, pillowtop beds, desk, laptop workspace

1. Best Western Plus Lake City

Lake City

William

NT$2,561

NT$2,881 total

includes taxes & fees

Aug 31 - Sep 1

Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers

2. Hampton Inn & Suites Lake City

Lake City

tracy

NT$3,605

NT$4,055 total

includes taxes & fees

Sep 13 - Sep 14

3. Tru by Hilton Lake City

Lake City

Kelly

NT$3,446

NT$3,877 total

includes taxes & fees

Sep 6 - Sep 7

Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board

4. Comfort Suites Lake City

Lake City

KHAJA

NT$2,929

NT$3,295 total

includes taxes & fees

Sep 13 - Sep 14

Suite, 1 Bedroom, Non Smoking | Private kitchen | Coffee/tea maker, fridge, microwave, dishwasher

5. Home2 Suites by Hilton Lake City

Lake City

William

NT$3,869

NT$4,353 total

includes taxes & fees

Sep 6 - Sep 7

6. Fairfield Inn & Suites Lake City

Lake City

Thomas

NT$3,244

NT$3,650 total

includes taxes & fees

Sep 6 - Sep 7

Desk, laptop workspace, blackout drapes, iron/ironing board

7. La Quinta Inn & Suite by Wyndham Lake City

Lake City

Nadia

NT$2,960

NT$3,329 total

includes taxes & fees

Sep 28 - Sep 29

Down comforters, pillowtop beds, blackout drapes, WiFi (free)

8. Super 8 by Wyndham Lake City

Lake City

Mari

NT$2,069

NT$2,328 total

includes taxes & fees

Aug 31 - Sep 1

Premium bedding, in-room safe, desk, iron/ironing board

Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers

9. Holiday Inn Express & Suites Live Oak by IHG

Live Oak

Trisha

NT$3,225

NT$3,548 total

includes taxes & fees

Sep 27 - Sep 28

10. Americas Best Value Inn Lake City

Lake City

Larissa

NT$2,134

NT$2,401 total

includes taxes & fees

Aug 31 - Sep 1

11. Quality Inn Lake City

Lake City

Lucille

NT$2,311

NT$2,600 total

includes taxes & fees

Sep 28 - Sep 29

Pillowtop beds, in-room safe, desk, blackout drapes

12. Days Inn by Wyndham Lake City I-75

Lake City

Brizheet

NT$1,998

NT$2,248 total

includes taxes & fees

Aug 31 - Sep 1

13. Holiday Inn & Suites Lake City by IHG

Lake City

Renee

NT$3,130

NT$3,522 total

includes taxes & fees

Sep 28 - Sep 29

14. Motel 6 – Lake City, Fl – Medical Center

Lake City

Pennee

NT$2,055

NT$2,312 total

includes taxes & fees

Aug 31 - Sep 1

Room, 2 Double Beds, Accessible, Smoking | WiFi (free), bed sheets

15. Econo Lodge Live Oak

Live Oak

James

NT$2,435

NT$2,678 total

includes taxes & fees

Aug 31 - Sep 1

16. Quality Inn White Springs Suwanee

White Springs

Pennee

NT$2,056

NT$2,261 total

includes taxes & fees

Sep 20 - Sep 21

Iron/ironing board, WiFi (free), bed sheets

Basic Single Room | Bathroom | Hair dryer, towels

17. Regal Inn

Lake City

Samuel

NT$1,962

NT$2,207 total

includes taxes & fees

Sep 1 - Sep 2

18. Driftwood Inn

Lake City

Jamie

NT$1,677

NT$1,887 total

includes taxes & fees

Aug 31 - Sep 1

19. Suwannee River Retreat: Pet Friendly, Private Dock

Branford

NT$10,181

NT$19,172 total

includes taxes & fees

Aug 31 - Sep 1

Room, Multiple Beds, Non Smoking (Oversize) | Desk, iron/ironing board, WiFi (free), alarm clocks

20. Baymont by Wyndham Lake City I-75

Lake City

Steve

NT$1,828

NT$2,056 total

includes taxes & fees

Aug 31 - Sep 1

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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Tru by Hilton Lake City

10/10 Excellent

"The room was very clean and each staff person was very helpful."

Hampton Inn & Suites Alachua I-75

10/10 Excellent

"Pasamos una estancia maravillosa lo recomendamos 100%"

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent

"Only complaint was the coffee pot was not clean"

Fairfield Inn & Suites Lake City

10/10 Excellent

"It was a nice hotel that was close to food and the highway"

Baymont by Wyndham Lake City I-75

10/10 Excellent

"Nice place"

More cheap stays in O Brien

Days Inn by Wyndham Lake City I-10

3430 N Us Highway 441 Lake City FL

NT$1,872

NT$2,106 total

Aug 31 - Sep 1

includes taxes & fees

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL

NT$2,311

NT$2,600 total

Sep 28 - Sep 29

includes taxes & fees

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

NT$2,561

NT$2,881 total

Aug 31 - Sep 1

includes taxes & fees

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL

NT$2,929

NT$3,295 total

Sep 13 - Sep 14

includes taxes & fees

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane Alachua FL

NT$3,345

NT$3,763 total

Sep 6 - Sep 7

includes taxes & fees

9.4/10 Exceptional! (553 reviews)

Tru by Hilton Lake City

284 NW Centurion Court Lake City FL

NT$3,446

NT$3,877 total

Sep 6 - Sep 7

includes taxes & fees

9.2/10 Wonderful! (1,003 reviews)

Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?

Best Western Plus Lake City, located 17.9 mi (28.8 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and La Quinta Inn & Suite by Wyndham Lake City. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

Best Western Plus Lake City: Provides a snack bar/deli, an indoor pool, and buffet. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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Find hotels in O Brien, FL from NT$2,056

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in O Brien

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for O Brien hotels

1. Best Western Plus Lake City

2. Hampton Inn & Suites Lake City

3. Tru by Hilton Lake City

4. Comfort Suites Lake City

5. Home2 Suites by Hilton Lake City

6. Fairfield Inn & Suites Lake City

7. La Quinta Inn & Suite by Wyndham Lake City

8. Super 8 by Wyndham Lake City

9. Holiday Inn Express & Suites Live Oak by IHG

10. Americas Best Value Inn Lake City

11. Quality Inn Lake City

12. Days Inn by Wyndham Lake City I-75

13. Holiday Inn & Suites Lake City by IHG

14. Motel 6 – Lake City, Fl – Medical Center

15. Econo Lodge Live Oak

16. Quality Inn White Springs Suwanee

17. Regal Inn

18. Driftwood Inn

19. Suwannee River Retreat: Pet Friendly, Private Dock

20. Baymont by Wyndham Lake City I-75

Learn more about O Brien

Top O Brien Hotel Reviews

Tru by Hilton Lake City

Hampton Inn & Suites Alachua I-75

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Fairfield Inn & Suites Lake City

Baymont by Wyndham Lake City I-75

More cheap stays in O Brien

Days Inn by Wyndham Lake City I-10

Quality Inn Lake City

Best Western Plus Lake City

Comfort Suites Lake City

Hampton Inn & Suites Alachua I-75

Tru by Hilton Lake City

Hotels in O Brien with star-rating

Frequently asked questions

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