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Check prices for these dates

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Jan 13 - Jan 14
Tomorrow
Jan 14 - Jan 15
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

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Our top choices for O Brien hotels

Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (479 reviews)
"Good overnight experience on a car trip. Nice staff."
United States
Luis
The price is NT$3,294
NT$3,706 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn & Suites Alachua I-75
Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (164 reviews)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is NT$3,130
NT$6,225 total
includes taxes & fees
Jan 14 - Jan 15
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,009 reviews)
"Great stay. Good breakfast. "
United States
Bob
The price is NT$3,509
NT$3,948 total
includes taxes & fees
Jan 22 - Jan 23
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Lobby
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (626 reviews)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is NT$1,946
NT$2,140 total
includes taxes & fees
Jan 26 - Jan 27
Quality Inn White Springs Suwanee
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,037 reviews)
"Room was clean and all the staff were very nice."
United States
Wayne
The price is NT$2,988
NT$3,361 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suite by Wyndham Lake City
Down comforters, pillowtop beds, blackout drapes, iron/ironing board
Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.2 out of 10, Good, (673 reviews)
"Clean room, friendly staff, fantastic food!"
United States
John
The price is NT$2,096
NT$2,358 total
includes taxes & fees
Jan 15 - Jan 16
Super 8 by Wyndham Lake City
Premium bedding, individually decorated, individually furnished, desk
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (187 reviews)
"The best part of this stay was a room with 2 king beds!!!!! Property was in excellent condition and front desk person was super. Highly recommend."
United States
Joyce
The price is NT$3,383
NT$3,806 total
includes taxes & fees
Jan 25 - Jan 26
Courtyard By Marriott Lake City
Free daily on-the-go breakfast
Tru by Hilton Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,007 reviews)
"Very clean and nice staff "
United States
renae
The price is NT$3,170
NT$3,567 total
includes taxes & fees
Jan 18 - Jan 19
Tru by Hilton Lake City
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board
Comfort Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, great breakfast and staff super friendly "
United States
Gary
The price is NT$3,386
NT$3,809 total
includes taxes & fees
Jan 18 - Jan 19
Comfort Suites Lake City
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (179 reviews)
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is NT$3,098
NT$3,486 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites Lake City
BBQ/picnic area
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.8 out of 10, Excellent, (1,005 reviews)
"Nice quiet and comfortable hotel a little gem."
Canada
Tim
The price is NT$2,123
NT$2,388 total
includes taxes & fees
Jan 14 - Jan 15
Americas Best Value Inn Lake City
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,006 reviews)
"Excellent staff and clean organized room"
United States
Robert
The price is NT$3,604
NT$4,055 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn & Suites Lake City
Pillowtop beds, in-room safe, desk, blackout drapes
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,002 reviews)
"Staff was great"
United States
Thomas
The price is NT$1,998
NT$2,248 total
includes taxes & fees
Jan 14 - Jan 15
Days Inn by Wyndham Lake City I-75
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,047 reviews)
"Great place to stay"
United States
Jack
The price is NT$3,004
NT$3,379 total
includes taxes & fees
Jan 18 - Jan 19
Best Western Plus Lake City
Lobby
Regal Inn

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (548 reviews)
"Comfortable bed, roomy bathroom. Negative:barn door separating bedroom & bathroom (affects privacy), no clothes hangers. "
United States
Linda
The price is NT$1,961
NT$2,206 total
includes taxes & fees
Jan 18 - Jan 19
Regal Inn
Premium bedding, desk, blackout drapes, soundproofing
Palms Garden Inn

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (583 reviews)
"Clean and nice staff "
United States
apollo
The price is NT$2,053
NT$2,310 total
includes taxes & fees
Jan 14 - Jan 15
Palms Garden Inn
Reception
The Blanche

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (166 reviews)
"Easy to access building and room with code provided; amazing bed and very clean."
United States
Ruth
The Blanche
Fountain
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (400 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is NT$2,822
NT$3,174 total
includes taxes & fees
Jan 16 - Jan 17
BlueGem Motel
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Great place"
United States
John
The price is NT$2,751
NT$3,095 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn & Suites Lake City by IHG
Pillowtop beds, desk, iron/ironing board, free WiFi
Quality Inn Lake City

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very Good, (960 reviews)
"Room clean and nice. Quiet location with many choices for food"
United States
Dennis
The price is NT$2,259
NT$2,541 total
includes taxes & fees
Feb 11 - Feb 12
Quality Inn Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

10/10 Excellent
"Spotless"
felisa 1-night trip
Posted 1 day ago
Americas Best Value Inn Lake City

More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

3340 W US Highway 90 Lake City FL
The price is NT$2,190 per night from Jan 14 to Jan 15
NT$2,190
NT$2,464 total
Jan 14 - Jan 15
includes taxes & fees
8.2/10 Very Good! (94 reviews)

Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Tru by Hilton Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool, and free self parking. Tru by Hilton Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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