A calm river with clear water, surrounded by dense trees and rocky banks.

Find hotels in O Brien, FL from NT$2,093

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Check prices for these dates

This weekend
Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

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Our top choices for O Brien hotels

Down comforters, pillowtop beds, blackout drapes, WiFi (free)

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (740 reviews)
"Comfortable beds, quiet, nice staff."
United States
Mari
The price is NT$2,107
NT$2,370 total
includes taxes & fees
Jul 23 - Jul 24
Super 8 by Wyndham Lake City
Desk, laptop workspace, iron/ironing board, cribs (free)

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,010 reviews)
"Great place to stay"
United States
Serhii
The price is NT$2,025
NT$2,278 total
includes taxes & fees
Jul 21 - Jul 22
Days Inn by Wyndham Lake City I-10
Lobby

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (686 reviews)
"Cheap and food enough"
United States
william
The price is NT$1,988
NT$2,186 total
includes taxes & fees
Jul 26 - Jul 27
Quality Inn White Springs Suwanee
Lobby

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (312 reviews)
"The room was fairly cheap and staff was friendly."
United States
James
The price is NT$2,355
NT$2,590 total
includes taxes & fees
Jul 20 - Jul 21
Econo Lodge Live Oak
Lobby

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,080 reviews)
"The breakfast was very good, bacon ,egg,potatoes,waffle mix,juices,cereal,room were clean staff was excellent."
United States
Glenda
The price is NT$3,027
NT$3,406 total
includes taxes & fees
Jul 18 - Jul 19
Best Western Plus Lake City
BBQ/picnic area

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"Staff was friendly the room was clean."
United States
Lorena
The price is NT$1,970
NT$2,216 total
includes taxes & fees
Jul 19 - Jul 20
Americas Best Value Inn Lake City
Exterior

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,143 reviews)
"Great stay"
United States
Priscilla J
The price is NT$3,044
NT$3,424 total
includes taxes & fees
Jul 26 - Jul 27
La Quinta Inn & Suite by Wyndham Lake City
Premium bedding, desk, blackout drapes, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (632 reviews)
"REALLY NICE PLACE, VERY CLEAN, WONDERFUL STAFF"
United States
Caroline
The price is NT$2,091
NT$2,352 total
includes taxes & fees
Jul 22 - Jul 23
Palms Garden Inn
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"Great place to stop for the night, very clean and great breakfast"
United States
RAFI
The price is NT$3,157
NT$3,552 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Suites Lake City
Lobby

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very Good, (1,019 reviews)
"Great breakfast; clean rooms; very friendly staff."
United States
Lucille
The price is NT$2,289
NT$2,575 total
includes taxes & fees
Jul 27 - Jul 28
Quality Inn Lake City
Lobby sitting area

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.4 out of 10, Good, (210 reviews)
"Amazing stay"
United States
Pennee
The price is NT$1,963
NT$2,209 total
includes taxes & fees
Jul 19 - Jul 20
Motel 6 – Lake City, Fl – Medical Center
Pillowtop beds, in-room safe, desk, blackout drapes

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,003 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is NT$2,034
NT$2,289 total
includes taxes & fees
Jul 19 - Jul 20
Days Inn by Wyndham Lake City I-75
Lobby

Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very Good, (609 reviews)
"First I was not sure if we wanted to stay there, but our room was pretty nice, price was excellent every thing was very clean. Lady at the front desk was very nice."
United States
Samuel
The price is NT$1,997
NT$2,246 total
includes taxes & fees
Jul 19 - Jul 20
Regal Inn
Reception

The Blanche

The Blanche
2.0 star property
Lake City
9.4 out of 10, Exceptional, (197 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is NT$4,780
NT$5,377 total
includes taxes & fees
Jul 20 - Jul 21
The Blanche
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
The price is NT$3,348
NT$3,766 total
includes taxes & fees
Aug 2 - Aug 3
Hampton Inn & Suites Lake City
Indoor pool

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (255 reviews)
"Cleaned place, good staff, basic breakfast"
United States
Adoniram
The price is NT$2,982
NT$3,355 total
includes taxes & fees
Jul 26 - Jul 27
Fairfield Inn & Suites Lake City
Terrace/patio

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (803 reviews)
"Great place to stay we will be back soon. "
United States
William
The price is NT$3,939
NT$4,431 total
includes taxes & fees
Aug 2 - Aug 3
Home2 Suites by Hilton Lake City
Outdoor spa tub

Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
Lake City
5.0 out of 10, (1,000 reviews)
"Desk & housekeeping staff were super helpful & friendly!"
United States
Cameron
The price is NT$1,860
NT$2,093 total
includes taxes & fees
Jul 22 - Jul 23
Baymont by Wyndham Lake City I-75
BBQ/picnic area

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (136 reviews)
"wonderful, quiet, a hide a way for a fun stay"
United States
Diane
The price is NT$2,825
NT$3,052 total
includes taxes & fees
Aug 4 - Aug 5
Cindys Motel
Lobby

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (577 reviews)
"Staff was awesome. Friendly and helpful. Room was clean and quiet."
United States
Patricia
The price is NT$2,490
NT$2,739 total
includes taxes & fees
Jul 21 - Jul 22
Quality Inn & Suites Live Oak I-10 Exit 283
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Best Western Plus Lake City

Best Western Plus Lake City

10/10 Excellent
"We were just in for one night and rested well!"
Joey 1-night trip
Posted 1 hour ago
Best Western Plus Lake City

More cheap stays in O Brien

Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

3598 W Us Highway 90 Lake City FL
The price is NT$1,860 per night from Jul 22 to Jul 23
NT$1,860
NT$2,093 total
Jul 22 - Jul 23
includes taxes & fees
5/10 (1,000 reviews)

Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool, and complimentary wired internet access. La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and First Federal Sportsplex in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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