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Find Luxury Hotels in Medical Center Area, MA

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Check availability on Medical Center Area Luxury Hotels

Our top choices for Medical Center Area luxury hotels

International cuisine
citizenM Boston Back Bay

citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
Fenway–Kenmore
9.4 out of 10, Exceptional, (2123)
"Great stay "
United States
Alexander
The price is NT$3,186
NT$3,710 total
includes taxes & fees
Dec 22 - Dec 23
citizenM Boston Back Bay
Lobby
The Westin Boston Seaport District

The Westin Boston Seaport District

The Westin Boston Seaport District
4.0 star property
Seaport District
9.2 out of 10, Wonderful, (2323)
"Nice hotel and great location."
United States
James Earl
The price is NT$3,561
NT$5,246 total
includes taxes & fees
Dec 22 - Dec 23
The Westin Boston Seaport District
Exterior
Hyatt Regency Boston

Hyatt Regency Boston

Hyatt Regency Boston
4.0 star property
Downtown Boston
9.0 out of 10, Wonderful, (1711)
"Amazing room, friendly staff"
United States
Ryan
The price is NT$4,006
NT$5,768 total
includes taxes & fees
Jan 11 - 2026/1/12
Hyatt Regency Boston
Premium bedding, pillowtop beds, minibar, in-room safe
Renaissance® Boston Seaport District

Renaissance® Boston Seaport District

Renaissance® Boston Seaport District
4.0 star property
Seaport District
9.0 out of 10, Wonderful, (1000)
"The room is so clean the hotel is beautiful the restaurant is amazing the service amazing to I recommend 😍"
United States
Marilyn
The price is NT$3,748
NT$5,648 total
includes taxes & fees
Dec 21 - Dec 22
Renaissance® Boston Seaport District
Peruvian cuisine
The Godfrey Hotel Boston

The Godfrey Hotel Boston

The Godfrey Hotel Boston
4.0 star property
Downtown Boston
9.4 out of 10, Exceptional, (4795)
"Nice hotel, great location."
United States
Oksana
The Godfrey Hotel Boston
Lobby
Hilton Boston Park Plaza

Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village
8.4 out of 10, Very Good, (3114)
"Great stay! "
United States
Charles
The price is NT$3,520
NT$5,382 total
includes taxes & fees
Jan 2 - 2026/1/3
Hilton Boston Park Plaza
In-room safe, blackout drapes, iron/ironing board, free WiFi
Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel

Copley Square Hotel, a FOUND Hotel
4.0 star property
Back Bay
8.6 out of 10, Excellent, (3895)
"Great for a short stay option. We stayed 2 days and it was perfect for our needs. "
United States
Rocco
The price is NT$2,513
NT$2,927 total
includes taxes & fees
Dec 25 - Dec 26
Copley Square Hotel, a FOUND Hotel
Rooftop terrace
YOTEL Boston

YOTEL Boston

YOTEL Boston
4.0 star property
Seaport District
8.6 out of 10, Excellent, (2353)
"Good hotel to stay "
United States
Luis
The price is NT$3,118
NT$5,098 total
includes taxes & fees
Dec 21 - Dec 22
YOTEL Boston
Exterior
Seaport Hotel Boston

Seaport Hotel Boston

Seaport Hotel Boston
4.0 star property
Seaport District
9.6 out of 10, Exceptional, (3823)
"Great weekend stay!"
United States
Amanda
The price is NT$5,327
NT$6,361 total
includes taxes & fees
Dec 21 - Dec 22
Seaport Hotel Boston
Exterior
InterContinental Boston by IHG

InterContinental Boston by IHG

InterContinental Boston by IHG
5.0 star property
Downtown Boston
9.4 out of 10, Exceptional, (1003)
"Room was clean, loved the pool, and the food was delicious! "
United States
Heather
The price is NT$5,173
NT$7,455 total
includes taxes & fees
Dec 22 - Dec 23
InterContinental Boston by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Medical Center Area Hotel Reviews

Omni Parker House

Omni Parker House

10/10 Excellent
"The hotel was "
Parker 1-night trip
Posted 15 hours ago
Omni Parker House

Frequently asked questions

Are you looking for a luxury hotel for your Medical Center Area vacation?
Expedia can help you arrange a flight to Boston, MA (BNH-Boston Harbor Seaplane Base) airport or Logan International Airport (BOS) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are an important consideration when you plan a trip, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Medical Center Area has to offer. Medical Center Area has some interesting things to see and do including Isabella Stewart Gardner Museum and Warren Anatomical Museum, so you might want to take in the local sights during your visit.
What's there to see and do in Medical Center Area?
Take in the sights and attractions that Medical Center Area offers with a visit to Isabella Stewart Gardner Museum, Warren Anatomical Museum, and Fenway Park. If you have a little extra time during your trip, you might want to make a stop at Copley Square and Harvard Square.
How can I get around Medical Center Area?
It's easier to get around town in style when you know your options. Take advantage of metro transit at Longwood Medical Area Station, Brigham Circle Station, and Museum of Fine Arts Station.

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