A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Find Family Hotels in Mayo, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mayo Family Hotels

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Mayo family-friendly hotels

An aerial view of a campground with RVs, a swimming pool, and tennis courts.
A wooden cabin with a kitchen, a bathroom, and a loft bedroom.
A wooden cabin with a porch, a front door, and a small window.
A covered outdoor dining area with a table and chairs, large windows, and a view of greenery.

1. Suwannee River Rendezvous

Suwannee River Rendezvous
Mayo
NT$2,858
NT$3,831 total
includes taxes & fees
Oct 8 - Oct 9
Suwannee River Rendezvous
A hotel reception area with a reception desk, seating area, and a view of the parking lot.
A hotel room with two beds, a bedside table with a lamp, a phone, and a window with curtains.
A dining area with wooden chairs and tables, a coffee machine, and a counter with various items.
A reception area with a wooden floor, a reception desk, a seating area with chairs, and a view through the glass doors to the outside.

2. Econo Lodge Live Oak

Econo Lodge Live Oak
Live Oak
NT$2,323
NT$2,555 total
includes taxes & fees
Sep 30 - Oct 1
Econo Lodge Live Oak
A commercial kitchen with coffee machines, a beverage dispenser, and various kitchen appliances.
A rectangular swimming pool with a safety ladder, surrounded by a low hedge and palm trees.
A hotel room with a desk, chair, TV, microwave, and refrigerator.
A spacious living area with a coffee station, teal sofas, and a ceiling fan.

3. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
Live Oak
  • Florida getaway offers outdoor pool, free breakfast, and music park access for memorable family trips.
NT$2,700
NT$2,970 total
includes taxes & fees
Oct 4 - Oct 5
Quality Inn & Suites Live Oak I-10 Exit 283
A modern hotel with a swimming pool, outdoor seating, and a covered area.
A modern kitchen with a white countertop, dark cabinets, and a glass backsplash.
A gym with treadmills, elliptical machines, and stationary bikes, equipped with mirrors and exercise mats.
A hotel room with a bed, a desk, a chair, a TV, a lamp, and a minibar.

4. Best Western Plus Madison

Best Western Plus Madison
Madison
NT$4,172
NT$4,694 total
includes taxes & fees
Oct 27 - Oct 28
Best Western Plus Madison
A wooden swing set in a park with a fenced area, a wooden structure, and a large tree.
A marina with docks, boats, and a water tower in the background.
A swimming pool with a covered area, surrounded by trees and a fence.
A beach with a sandy shore and a calm sea.

5. Steinhatchee River Inn

Steinhatchee River Inn
Steinhatchee
NT$3,653
NT$5,043 total
includes taxes & fees
Sep 27 - Sep 28
Steinhatchee River Inn
A two-story house with a covered porch, a staircase, and a large lawn.

6. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
NT$10,249
NT$19,299 total
includes taxes & fees
Sep 28 - Sep 29
Suwannee River Retreat: Pet Friendly, Private Dock
View all properties

Choose what matters most at family-friendly hotels in Mayo

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Mayo Hotel Reviews

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

10/10 Excellent
"Okey"
Rolando 1-night trip
Posted 4 days ago
Quality Inn & Suites Live Oak I-10 Exit 283
Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

8/10 Good
"I chose this hotel because it was close to the highway and the pictures looked good. I did find my room to be fairly well appointed, although there was a space for a microwave, but none there. There is a microwave in the lobby. I was comfortable and enjoyed the bagel and juice and coffee for breakfast. It was kind of strange that the first room I was assigned to was not vacated. The lobby host was very apologetic and gave me a different room. Also, there were highway construction workers staying there, and they were hanging out on the stairs right outside my room, joking around and some smoking pot. That made me feel a little uncomfortable, but I just happened to get the room right by where they were. I could’ve easily landed somewhere where I felt more comfortable."
Paige 1-night trip
Posted 7 days ago
Days Inn by Wyndham Madison
Steinhatchee River Inn

Steinhatchee River Inn

10/10 Excellent
"A charming hotel located on the Steinhatchee River not far from the Gulf. Friendly staff, comfortable rooms, pool with a view. A great two night stay!"
Gregory 2-night trip
Posted 1 month ago
Steinhatchee River Inn

Frequently asked questions

What's Mayo like for family-friendly vacations?
The destination of Mayo is a great choice if you've been thinking about a vacation with your kids. The parks here makes this a great vacation spot for families.
When's the best time to book a family-friendly vacation in Mayo?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Mayo is 51 inches.
What's there to see and do with your family in Mayo?
While you and the family are vacationing in Mayo, you might want to check out some of the attractions here such as Lafayette County Library, Suwannee River, and Veteran's Memorial Park of Mayo. Make sure you have lots of time for activities like Steinhatchee Falls and Suwannee River State Park.

Explore a world of travel with Expedia