Lower Florida Keys Vacations

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Where to stay in Lower Florida Keys

Find the best Lower Florida Keys areas and neighborhoods for the activities you enjoy most. Learn more about Lower Florida Keys
A white building with shutters, palm trees, and a lawn.

Old Town Key West

4 out of top 10 points of interest in this area

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

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A coastal town with a prominent building featuring a blue awning, a chicken shack, and a store with colorful merchandise.

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

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A two-story house with green shutters and a wooden balcony.

Key West Historic District

2 out of top 10 points of interest in this area

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

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A marina with yachts docked, a prominent red building, and a coastal cityscape in the background.

New Town

Though New Town might not have many top sights, you can venture to the surrounding area to see attractions like Smathers Beach and Fort East Martello Museum and Gallery.

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A sunset over the ocean with scattered clouds.

Uptown - Upper Duval

If you're spending some time in Uptown - Upper Duval, Duval Street and Florida Keys Beaches are top sights worth seeing.

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Find the Best Lower Florida Keys Vacation Packages

Lower Florida Keys Hotel Deals

Parmer's Resort

Parmer's Resort

565 Barry Avenue Summerland Key FL
Fully refundableReserve now, pay when you stay
NT$4,035
NT$5,579 total
Nov 1 - Nov 2
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
"Just a fantastic property, wonderful staff, great amenities, so many waterfront places to chill. Immaculate grounds with a laid back vibe, loved it!!"

Reviewed on 2026/10/4

Parmer's Resort
Sugarloaf Key Hotel at KOA Resort

Sugarloaf Key Hotel at KOA Resort

251 Co Rd 939 Summerland Key FL
9.8/10 Exceptional! (643 reviews)
"Room was clean, we used the pool, hot tub, marina boat rental, bar, store and the beach area. Everything was very nice. It’s a short ride to Bahia Honda beaches and Key West. The bar, marina and store were all very nice and useful."

Reviewed on 2026/10/3

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Sugarloaf Key Hotel at KOA Resort
Looe Key Reef Resort

Looe Key Reef Resort

27340 Overseas Highway Summerland Key FL
Fully refundableReserve now, pay when you stay
NT$3,214
NT$3,616 total
Oct 5 - Oct 6
includes taxes & fees
7.8/10 Good! (1,002 reviews)
"The room was super clean. The fact that we can keep a boat docked right behind our room is amazing. There is a tiki bar literally right in front of the room is a plus. Check out was easy and quick as well as check in. I mean best decision ever."

Reviewed on 2026/10/4

Looe Key Reef Resort
See all 3,421 properties in Lower Florida Keys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Lower Florida Keys attractions

A street with a pharmacy, a theater, and a yellow building.

Duval Street

9.2/10 (20,928 reviews)
Along one of the southernmost streets in the continental U.S., enjoy a lively area filled with shops, pubs, restaurants and lots of sidewalk acts and vendors.
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A wooden signpost with city names and distances, a beach with umbrellas, and lounge chairs.

Florida Keys Beaches

8.4/10 (858 reviews)
Nothing says vacation like spending a carefree day at Florida Keys Beaches, a popular beach in Long Beach Estates.
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A colorful monument with text indicating it is the Southernmost Point of the Continental U.S.A. in Key West, Florida.

Southernmost Point

8.8/10 (17,214 reviews)
Snap a memorable photograph from the edge of North America at this monumental landmark.
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A sign reading "Welcome to Mallory Square" with an American flag, a red and white striped awning, and a statue of a man in a blue shirt and straw hat.

Mallory Square

9.2/10 (15,939 reviews)
Arrive at this square at day’s end to find street performers, food carts and one of the most beautiful sunsets in the United States.
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A beach with white sand, palm trees, and a building in the background.

Smathers Beach

8.4/10 (8,320 reviews)
Key West’s popular party beach has an electric atmosphere on the weekends and is a destination for water sports lovers.
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A two-story colonial-style building with a balcony, surrounded by lush greenery and palm trees.

Ernest Hemingway Home and Museum

9.2/10 (8,543 reviews)
Meet six-toed cats and watch as the life of one America’s great writers unfolds before your eyes at his former home.
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A coastal fortification with a staircase leading to a higher platform, overlooking the sea.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
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A wooden sign with information about South Beach, Key West, Florida, including public beach status, restaurant hours, and beach chair rental.

South Beach

8.4/10 (5,461 reviews)
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
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Frequently asked questions

How much does a Lower Florida Keys vacation package cost?
Starting from as low as , a package is your portal to low-priced travel. Custom build your Lower Florida Keys getaway by selecting from our wide range of hotels, airfares and rental cars.
How do I get a cheap travel package to Lower Florida Keys?
One of the simplest ways to save money (and time) is to combine your bookings with Expedia. Hotels, flights, activities and rental cars — we've got everything you need. Pick and choose a combination that best fits you and watch your savings pile up. We know a travel package is never a one-size-fits-all. That's why we offer over 550 partner airlines and 1,000,000 hotels from all over the world, which lets you customize your Lower Florida Keys adventure.
Where should I stay in Lower Florida Keys?
You'll love Key West. Renowned sights, such as Ernest Hemingway Home and Museum and Audubon House and Tropical Gardens, will keep you busy in this vibrant city.
What are the top hotels in Lower Florida Keys?
When it comes to properties in Key West, Margaritaville Beach House Key West and Southernmost Beach Resort are two excellent options. If you're also heading to Cudjoe Key, 24 North Hotel Key West and Faro Blanco Resort & Yacht Club will make you feel right at home.
How far in advance should I book my Lower Florida Keys vacation?
To land discount prices, book ASAP. Air carriers usually start selling tickets, along with some of the lowest fares, up to a year prior to departure. Hotels, activities and car rental should also be booked early so you can have the pick of the bunch. If you were hoping for a last-minute getaway in Lower Florida Keys, there are always lots of great bargains to be had on Expedia. Book your escape today!
What does an Expedia Lower Florida Keys travel package include?
Expedia has all you need to book your Lower Florida Keys escape, but how your package is structured is totally up to you. Pick from a combination of rental cars, flights and hotels. Looking for some activities to keep you busy? Once you've made your booking, you can add them on too. No matter your style or budget, there's a package to meet your needs.
What should I know before booking a Lower Florida Keys travel package?
Our prices are always low. However, you'll enjoy even more bargains if you book your flights, hotels and car rentals together. With an Expedia travel package, you'll always get transparent pricing and a great range of choice.
Can I choose my airline with a Lower Florida Keys Expedia vacation package?
Yes — that's the beauty of an Expedia vacation package. You're in control. We have more than 550 partner airlines worldwide, so you have loads of choice when planning your Lower Florida Keys escape.
If I'm not able to travel, can I cancel my Lower Florida Keys vacation package?
Don't stress if you're rethinking your Lower Florida Keys vacation package — it's possible to cancel or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We understand life can sometimes throw a spanner in the works, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we're ready to help.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.