A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Key Largo Luxury Hotels

Tonight
Sep 6 - Sep 7
Tomorrow
Sep 7 - Sep 8
Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20

Our top choices for Key Largo luxury hotels

An aerial view of a resort with a large pool, palm trees, and a beach.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A beachside patio with lounge chairs, a table, and a view of the ocean.

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
NT$8,068
NT$10,821 total
includes taxes & fees
Sep 20 - Sep 21
Playa Largo Resort & Spa, Autograph Collection
A hammock on a sandy beach with a view of the sea and a tree overhead.
A spacious interior with a high ceiling, large windows, and a central chandelier.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
NT$7,498
NT$10,180 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A poolside area with blue chairs and a thatched-roof structure.

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
NT$6,929
NT$9,061 total
includes taxes & fees
Sep 8 - Sep 9
Reefhouse Resort & Marina
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A gated entrance to a resort with palm trees and a clear sky.
A pool area with clear blue water, white lounge chairs, and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
NT$12,814
NT$16,416 total
includes taxes & fees
Sep 8 - Sep 9
The Islands of Islamorada
A wooden deck with a pergola, surrounded by lush greenery and a sandy area.
A two-story house with a wooden deck leading to the entrance, surrounded by large trees and potted plants.
A modern interior with a red sofa, wooden flooring, stone wall, and a kitchen area.
A modern room with a red sofa, stone wall, wooden ceiling, and a painting.

5. Find Peace - Tiny House in Japanese Garden

Find Peace - Tiny House in Japanese Garden
Homestead
NT$14,396
NT$21,281 total
includes taxes & fees
Sep 8 - Sep 9
Find Peace - Tiny House in Japanese Garden
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A coastal resort with a beach, a swimming pool, and multiple buildings.
A resort with a pool, beach, and ocean view.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.

6. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
NT$5,796
NT$8,835 total
includes taxes & fees
Sep 13 - Sep 14
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A bar area with a wooden counter, bar stools, and potted plants.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A paved pathway leading to a beach with palm trees and a view of the ocean.

7. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
NT$6,194
NT$9,103 total
includes taxes & fees
Sep 13 - Sep 14
Islander Resort
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A tropical resort with a swimming pool, palm trees, and a waterfall.

8. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
NT$4,714
NT$7,618 total
includes taxes & fees
Sep 15 - Sep 16
Cheeca Lodge & Spa
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A resort with a pool surrounded by palm trees and a view of the ocean.
A row of colorful beach huts with palm trees in the background.
A beach with colorful buildings, kayaks, and lounge chairs.

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
La Siesta Resort & Villas
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A resort pool with palm trees, beach chairs, and umbrellas.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A beach with palm trees, a dock, and lounge chairs.

10. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
NT$4,891
NT$7,816 total
includes taxes & fees
Sep 15 - Sep 16
Amara Cay Resort
View all properties

Top Key Largo Hotel Reviews

Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"My favorite place to stay when i dive. Everything about it is great for the price. The beds are top notch i love the full kitchen and balcony. Its always clean. Amenities are wonderful, staff is always available. Feels like an apartmnet."
Jennifer 1-night trip
Posted 2 hours ago
Waterside Suites & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Very clean and nice hotel just one thing need to improve hot water in the shower"
Rosibel 2-night trip
Posted 4 hours ago
Bayside Inn Key Largo
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Everything was excellent, the people are friendly and helpful, I’ll check me back soon."
Antonio 2-night trip
Posted 7 hours ago
Reefhouse Resort & Marina
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"Great location, perfect for relaxing. We enjoyed watching the sunset on the dock in the provided Adirondack chairs"
Kim 2-night trip
Posted 8 hours ago
The Pelican Key Largo Cottages
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"I thoroughly enjoyed my stay at Sunset Cove. I will go back there again if I am in the area. The rooms were clean and offered more than I expected with a full-size refrigerator microwave and stocked with plenty of dinnerware if needed , bathrooms were spacious. Enjoyed the amenities, such as paddle boarding and kayaking and bicycling. Everyone was friendly! a perfect island retreat. !!!"
Cindy 1-night trip
Posted 8 hours ago
Sunset Cove Beach Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

8/10 Good
"Nice beach"
Monica 2-night trip
Posted 10 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This property was clean and the staff was very friendly. It is a cozy little get away in Key Largo with nice restaurants close by. Would definitely stay again."
P 2-night trip
Posted 5 days ago
Amoray Dive Resort
Azul del Mar

Azul del Mar

10/10 Excellent
"A amazing location with private beach swimming pool next door and restaurants nearby Ideal chill out spot"
Stephen 2-night trip
Posted 8 days ago
Azul del Mar

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a little extra time during your trip, you might want to make a stop at MarineLab Undersea Laboratory and Caribbean Club Bar.

Explore a world of travel with Expedia