A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Luxury Hotels in Key Largo, FL

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Check availability on Key Largo Luxury Hotels

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Key Largo luxury hotels

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
NT$8,352
NT$11,146 total
includes taxes & fees
Oct 11 - Oct 12
Playa Largo Resort & Spa, Autograph Collection

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
NT$8,328
NT$11,120 total
includes taxes & fees
Sep 30 - Oct 1
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
NT$6,319
NT$8,380 total
includes taxes & fees
Sep 28 - Sep 29
Reefhouse Resort & Marina

4. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
NT$13,147
NT$16,803 total
includes taxes & fees
Oct 1 - Oct 2
The Islands of Islamorada

5. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Experience seaside opulence with private beach access, three outdoor pools, and oceanfront dining at this beachfront Matecumbe resort.
NT$4,732
NT$7,645 total
includes taxes & fees
Sep 29 - Sep 30
Cheeca Lodge & Spa

6. Amara Cay Resort

Amara Cay Resort
Matecumbe
  • Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.
NT$4,909
NT$7,844 total
includes taxes & fees
Sep 30 - Oct 1
Amara Cay Resort

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
  • Seaside elegance awaits at this Islamorada resort with 3 pools, diverse dining, and a marina.
NT$6,580
NT$9,724 total
includes taxes & fees
Oct 13 - Oct 14
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Islander Resort

Islander Resort
Matecumbe
  • Beachfront luxury awaits at Florida Keys haven with private shores, poolside bars, and lavish lanai rooms.
NT$9,088
NT$12,546 total
includes taxes & fees
Oct 27 - Oct 28
Islander Resort
View all properties

Top Key Largo Hotel Reviews

Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Location was great!"
Desiree 2-night trip
Posted 23 hours ago
Bayside Inn Key Largo
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Great getaway for weekend and bring the dog"
Brian 4-night trip
Posted 23 hours ago
Sunset Cove Beach Resort
Azul del Mar

Azul del Mar

10/10 Excellent
"This was a great place to stay"
Loney 1-night trip
Posted 4 days ago
Azul del Mar
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Decent hotel to stay at. Breakfast was pricey, we searched elsewhere to eat. We couldn’t connect to the WiFi in the room the whole week. Their tech tried to help, but no luck. Close to restaurants and sites that we wanted to go visit."
Ann 5-night trip
Posted 9 days ago
Holiday Inn Key Largo by IHG

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
During your visit, you might want to enjoy the sunsets and boating which Key Largo is known for.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Another upscale choice for your vacation is Reefhouse Resort & Marina.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

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