Find Luxury Hotels in Key Largo, FL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Key Largo Luxury Hotels

Our top choices for Key Largo luxury hotels

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,000 reviews)
"Everything was great. Very clean and excellent location"
United States
peter
The price is NT$15,906
NT$19,638 total
includes taxes & fees
Feb 8 - Feb 9
Playa Largo Resort & Spa, Autograph Collection

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,001 reviews)
"Everything about this place was perfect, location, staff, comfort, and amenities. Can’t wait to go back!"
United States
Fabiane
The price is NT$11,150
NT$14,287 total
includes taxes & fees
Feb 3 - Feb 4
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,302 reviews)
"Nice resort "
United States
Danilo
The price is NT$9,461
NT$12,958 total
includes taxes & fees
Jan 29 - Jan 30
Cheeca Lodge & Spa

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (70 reviews)
"Amazing stay, can’t wait to stay there again!"
United States
Anonymous traveler
The price is NT$19,258
NT$23,409 total
includes taxes & fees
Jan 27 - Jan 28
The Islands of Islamorada

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,011 reviews)
"Rooms are clean, staff is friendly and the place is beautifull"
United States
James
The price is NT$9,619
NT$12,957 total
includes taxes & fees
Jan 29 - Jan 30
Islander Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (134 reviews)
"Great place"
United States
Kathryn
The price is NT$10,731
NT$14,173 total
includes taxes & fees
Jan 29 - Jan 30
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,273 reviews)
"Beautiful grounds, very comfortable beds, provided water taxi between their 3 resorts, pool area with tiki bar very nice. "
United States
Judith
The price is NT$6,809
NT$9,973 total
includes taxes & fees
Jan 26 - Jan 27
Amara Cay Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,003 reviews)
"Great accommodations, very peaceful setting "
United States
Susan
The price is NT$9,798
NT$13,335 total
includes taxes & fees
Jan 26 - Jan 27
La Siesta Resort & Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Key Largo Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Key Largo?
Known for its sunsets and boating, Key Largo also has some interesting things to see and do including Everglades National Park, so you may want to take in the local sights during your visit.
What's the best high-end place to stay in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a luxury resort with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in Key Largo?
Planning for the weather is an important factor for making your trip to Key Largo a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 83°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Key Largo is 44 inches.
What's there to see and do in Key Largo?
Take in some sights and attractions while you're in Key Largo by visiting Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a little extra time during your trip, you might want to make a stop at John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.

Explore a world of travel with Expedia