
Find hotels in Isle of Palms South, Jacksonville
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Our top choices for Isle of Palms South hotels

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin21.1 km from Isle of Palms South
7.4 out of 10, Good, (425 reviews)

AC Hotel Jacksonville St Johns Town Center
AC Hotel Jacksonville St Johns Town Center8.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (184 reviews)

Seahorse Oceanfront Inn
Seahorse Oceanfront Inn6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (655 reviews)

Home2 Suites By Hilton Jacksonville Downtown
Home2 Suites By Hilton Jacksonville Downtown24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (299 reviews)

Holiday Inn Express Jacksonville - Blount Island by IHG
Holiday Inn Express Jacksonville - Blount Island by IHG20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,010 reviews)

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,051 reviews)

The Hotel Palms Courtyard
The Hotel Palms Courtyard6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (294 reviews)

TownePlace Suites by Marriott® Jacksonville Mayport
TownePlace Suites by Marriott® Jacksonville Mayport9.7 km from Isle of Palms South
9.8 out of 10, Exceptional, (92 reviews)

Margaritaville Jacksonville Beach
Margaritaville Jacksonville Beach4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3,770 reviews)

Hilton Jacksonville At Mayo Clinic
Hilton Jacksonville At Mayo Clinic1.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (179 reviews)

Courtyard by Marriott Jacksonville Beach Oceanfront
Courtyard by Marriott Jacksonville Beach Oceanfront5.2 km from Isle of Palms South
8.4 out of 10, Very Good, (1,003 reviews)

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,002 reviews)

Best Western Oceanfront
Best Western Oceanfront4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)

Holiday Inn Express Hotel & Suites Jacksonville South I-295 by IHG
Holiday Inn Express Hotel & Suites Jacksonville South I-295 by IHG20 km from Isle of Palms South
8.8 out of 10, Excellent, (860 reviews)

Hampton Inn Jacksonville East Regency Square
Hampton Inn Jacksonville East Regency Square12.8 km from Isle of Palms South
8.6 out of 10, Excellent, (1,002 reviews)

San Marco Inn East
San Marco Inn East19.5 km from Isle of Palms South
8.4 out of 10, Very Good, (1,389 reviews)

Wyndham Garden Jacksonville
Wyndham Garden Jacksonville15.3 km from Isle of Palms South
7.8 out of 10, Good, (1,827 reviews)

Tru by Hilton Jacksonville South Mandarin
Tru by Hilton Jacksonville South Mandarin21.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Isle of Palms South
Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most.

Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Photo by Ryan Ketterman
Open Photo by Ryan Ketterman
Downtown Jacksonville
Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Photo by Russell Hewatt
Open Photo by Russell Hewatt
Sawgrass
Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach
If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.
Top Isle of Palms South Hotel Reviews

Holiday Inn Express Jacksonville South Bartram Prk by IHG
10/10 Excellent
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Hotels in top Jacksonville neighborhoods
- Hotels in Amelia City
- Hotels in South Ponte Vedra Beach
- Hotels in Downtown Jacksonville
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Hotels near popular Jacksonville Attractions
- Hotels near St. Johns Town Center
- Hotels near Mayo Clinic Florida
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- Hotels near Jacksonville Zoo and Gardens
- Hotels near TPC Sawgrass
- Hotels near EverBank Stadium
- Hotels near Jacksonville University
- Hotels near VyStar Veterans Memorial Arena
More Accommodation Types in Isle of Palms South
Isle of Palms South Hotels by Star Rating
Explore more hotels
- Best Western Oceanfront
- Weekly Inn
- Hyatt Place Jacksonville / St. Johns Town Center
- Delta Hotels by Marriott™ Jacksonville Deerwood
- Holiday Inn Express Jacksonville South Bartram Prk by IHG
- Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
- Comfort Suites Baymeadows Near Butler Blvd
- Holiday Inn Express Jacksonville Beach by IHG
- Candlewood Suites Jacksonville Southpoint by IHG
- Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
- Baymont by Wyndham Jacksonville/Butler Blvd
- Dune House Hotel and Spa
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General
- Visit Berkeley Manor
- Visit Downtown Orlando
- Visit Little Haiti
- Visit Paver Park
- Visit Coconut Grove
- Visit Hyde Park
- Visit Birch Park Finger Streets
- Visit Riverwalk Fort Lauderdale
- Visit Ybor City
- Visit City Place
- Visit Historic Downtown Kissimmee
- Visit Rosemary Beach
- Visit Daisy Lake Camp Sites
- Visit Little Havana



















































































