Find hotels in Isle of Palms South, Jacksonville

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Mar 23 - Mar 24
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Mar 24 - Mar 25
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Mar 27 - Mar 29
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Our top choices for Isle of Palms South hotels

Premium bedding, desk, blackout drapes, iron/ironing board

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.1 km from Isle of Palms South
7.4 out of 10, Good, (425 reviews)
"The carpet really is in bad condition, and smell bad. Yes the property it's close to many stores and restaurants. "
United States
Sandra
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
8.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (184 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
AC Hotel Jacksonville St Johns Town Center
Exterior

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.8 km from Isle of Palms South
8.8 out of 10, Excellent, (655 reviews)
"Great hotel "
United States
Jameida
Seahorse Oceanfront Inn
Terrace/patio

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.2 km from Isle of Palms South
9.2 out of 10, Wonderful, (299 reviews)
"Clean room, friendly staff, good breakfast."
United States
Lisa
Home2 Suites By Hilton Jacksonville Downtown
Exterior

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.2 km from Isle of Palms South
8.8 out of 10, Excellent, (1,010 reviews)
"Staff was incredibly friendly, breakfast was great, nice location."
United States
Melissa
Holiday Inn Express Jacksonville - Blount Island by IHG
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,051 reviews)
"Great staff and Clean hotel "
United States
Tyniesha
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Standard Room, 1 King Bed, Non Smoking | Down comforters, minibar, iron/ironing board, WiFi

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
6.6 km from Isle of Palms South
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The Hotel Palms Courtyard
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms South
9.8 out of 10, Exceptional, (92 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
TownePlace Suites by Marriott® Jacksonville Mayport
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.8 km from Isle of Palms South
9.0 out of 10, Wonderful, (3,770 reviews)
"Nice spot, friendly staff, nice bar and great beach location. "
United States
Keith
Margaritaville Jacksonville Beach
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
1.9 km from Isle of Palms South
9.4 out of 10, Exceptional, (179 reviews)
"Great place to stay"
United States
Judy
Hilton Jacksonville At Mayo Clinic
41-inch Smart TV with cable channels

Weekly Inn

Weekly Inn
2.0 star property
14.7 km from Isle of Palms South
7.6 out of 10, Good, (1,174 reviews)
"Always a nice stay. cool florida vibe. "
United States
Matthew
Weekly Inn
Room, 2 Queen Beds, Balcony, Oceanfront (Balcony) | Premium bedding, in-room safe, desk, laptop workspace

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5.2 km from Isle of Palms South
8.4 out of 10, Very Good, (1,003 reviews)
"Great location and friendly staff. "
United States
Harry
Courtyard by Marriott Jacksonville Beach Oceanfront
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms South
9.2 out of 10, Wonderful, (1,002 reviews)
"Great stay all around "
United States
Jeffrey
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.6 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)
"Great location, breakfast was delicious "
United States
Paul
Best Western Oceanfront
Front of property - evening/night

Holiday Inn Express Hotel & Suites Jacksonville South I-295 by IHG

Holiday Inn Express Hotel & Suites Jacksonville South I-295 by IHG
2.5 star property
20 km from Isle of Palms South
8.8 out of 10, Excellent, (860 reviews)
"Clean room, comfortable beds. Overall a great experience. "
United States
Juliana
Holiday Inn Express Hotel & Suites Jacksonville South I-295 by IHG
Reception

Hampton Inn Jacksonville East Regency Square

Hampton Inn Jacksonville East Regency Square
2.5 star property
12.8 km from Isle of Palms South
8.6 out of 10, Excellent, (1,002 reviews)
"We stay here every time we visit family, very convenient, clea, friendly and quiet. "
United States
Robin
Hampton Inn Jacksonville East Regency Square
Double Room, 2 Queen Beds, Non Smoking | In-room dining

San Marco Inn East

San Marco Inn East
3.0 star property
19.5 km from Isle of Palms South
8.4 out of 10, Very Good, (1,389 reviews)
"Can't beat it. Great place to stay. Very clean and well maintained. This is where I will stay on my next trip to Jacksonville. "
United States
Frank
San Marco Inn East
Reception

Midtown Lodge

Midtown Lodge
2.5 star property
18.9 km from Isle of Palms South
8.0 out of 10, Very Good, (616 reviews)
"The cleanness and the bedding was superb. The staff nice and welcoming too."
United States
Assan
Midtown Lodge
Lobby

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.3 km from Isle of Palms South
7.8 out of 10, Good, (1,827 reviews)
"A great budget motel surrounded by other national branded motels."
United States
Darryl
Wyndham Garden Jacksonville
Exterior

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
21.4 km from Isle of Palms South
9.0 out of 10, Wonderful, (1,002 reviews)
"Great property! "
United States
Nancy
Tru by Hilton Jacksonville South Mandarin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most.
Fernandina Beach, Florida, USA Historic Downtown 1959

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville which includes skyline, a city and a river or creek
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Ponte Vedra Beach.
Photo by Russell Hewatt
Open Photo by Russell Hewatt

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Jacksonville_StJohnsTownCenter_6127793_05

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Pitbull Terrier

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms South Hotel Reviews

Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

10/10 Excellent
"Very pleasant stay"
Patricia Denise 3-night trip
Posted 3 hours ago
Holiday Inn Express Jacksonville South Bartram Prk by IHG

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Frequently asked questions

What is Isle of Palms South like?
Travelers will be sure to find plenty to entertain them in Jacksonville Beach's Isle of Palms South neighborhood.
How many hotels will I be able to find in Isle of Palms South?
With 11 Expedia hotels and other accommodations in Isle of Palms South to choose from, this is a good starting point for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms South, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Isle of Palms South.
Where can I learn more about changing or cancelling my trip to Isle of Palms South?
To find more details about changing or cancelling your trip to Isle of Palms South, go to https://www.expedia.com/service/.
What are the top things to see and do in Isle of Palms South?
Cradle Creek Preserve, Windsor Parke Golf Club, and Jacksonville Beach Golf Club are just a few of the places to visit in and around Isle of Palms South. Windsor Commons Shopping Center and Harbor City Municipal Golf Course are also worth a visit when you're out sightseeing in Jacksonville Beach.