Find Resorts & Hotels with Spas in Isle of Palms, FL

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Isle of Palms Resorts & Hotels with Spas

Tonight
Jul 8 - Jul 9
Tomorrow
Jul 9 - Jul 10
This weekend
Jul 11 - Jul 13
Next weekend
Jul 18 - Jul 20

Top Isle of Palms Resorts & Hotels with Spas

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Reception

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (406)
"The place was clean and staff was wonderful. Will be staying again!"
The price is NT$4,570
NT$5,187 total
includes taxes & fees
Jul 27 - Jul 28
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Looking for a spa hotel in Isle of Palms?
Soothe the senses with some time in one of our wonderful spa hotels. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your weekend away.
What's there to see and do in Isle of Palms?
When you're in Isle of Palms, enjoy exploring the sights and attractions here including St. Johns Town Center, EverBank Stadium, and Jacksonville Cruise Terminal. If you have extra time while you're in the area, you might want to see Jacksonville Naval Air Station and Adventure Landing.
What is a Isle of Palms spa hotel?
Spa hotels in Isle of Palms provide lodging and have a full on-site spa which offers services like massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.