Find Adults Only Resorts & Hotels in Isle of Palms, FL
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Isle of Palms Adults Only Resorts & Hotels
Top Isle of Palms Adults Only Resorts & Hotels
Recent reviews of Isle of Palms hotels
Recent reviews of Isle of Palms hotels
Omni Amelia Island Resort & Spa
5/5 Excellent
"Beautiful resort! The staff was amazing and was constantly entertaining kids around the pool and very helpful. The food was really good too. Would definitely go back"
A verified traveler stayed at Omni Amelia Island Resort & Spa
Posted 5 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Isle of Palms
- Adults Only Resorts & Hotels in Southside
- Adults Only Resorts & Hotels in Northside
- Adults Only Resorts & Hotels in South Ponte Vedra Beach
- Adults Only Resorts & Hotels in Downtown Jacksonville
- Adults Only Resorts & Hotels in Arlington
- Adults Only Resorts & Hotels in American Beach
- Adults Only Resorts & Hotels in Sawgrass
- Adults Only Resorts & Hotels in Northwest
- Adults Only Resorts & Hotels in Palm Valley
- Adults Only Resorts & Hotels in Westside
More Accommodation Types in Isle of Palms
Hotels near popular Jacksonville Attractions
- Hotels near St. Johns Town Center
- Hotels near Mayo Clinic Florida
- Hotels near Jacksonville Cruise Terminal
- Hotels near Jacksonville Naval Air Station
- Hotels near EverBank Stadium
- Hotels near Mayport Naval Station
- Hotels near Jacksonville Zoo and Gardens
- Hotels near University of North Florida
- Hotels near World Golf Village
- Hotels near TPC Sawgrass
Isle of Palms Hotels by Star Rating
Explore more hotels
- Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG
- Hampton Inn Jacksonville Beach/Oceanfront
- Southbank Hotel by Marriott Jacksonville Riverwalk
- Weekly Inn
- Comfort Suites Baymeadows Near Butler Blvd
- WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk
- Hyatt Place Jacksonville Airport
- Scottish Inn Jacksonville Downtown
- One Ocean Resort and Spa
- Springhill Suites By Marriott Jacksonville Beach Oceanfront
- The Villas of Amelia Island
- Baymont by Wyndham Jacksonville/Butler Blvd
- Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
- Baymont by Wyndham Jacksonville Airport
- Marriott Jacksonville Downtown
- Delta Hotels by Marriott Jacksonville Deerwood
- Midtown Lodge
- Holiday Inn Express Jacksonville Beach by IHG
- Hyatt Place Jacksonville / St. Johns Town Center
- Hilton Garden Inn Jacksonville JTB/Deerwood Park
More ways to book
Expedia's Latest Trends
Hotels
Flights
- Flights from Taipei (TSA) to Naha (OKA)
- Flights from Tribhuvan Intl.
- Flights from Taoyuan City (TPE) to Gdansk (GDN)
- Flights from Taoyuan City (TPE) to San José (SJO)
- Flights from Southern California Logistics
- Flights from Taoyuan City (TPE) to Narsarsuaq (UAK)
- Flights from Taipei (TSA) to Shanghai (SHA)
- Flights from Taoyuan City (TPE) to Bilbao (BIO)