Find hotels near Historic Main Street, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Feb 3 - Feb 4
Tomorrow
Feb 4 - Feb 5
This weekend
Feb 6 - Feb 8
Next weekend
Feb 13 - Feb 15

Filter by

Guest rating
Guest rating
Star rating

Top Historic Main Street Hotel Reviews

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

10/10 Excellent
"We enjoyed our stay. Both couples, we liked the shower set ups a lot. Shout out to Mary Jo - I needed an item and she promptly got me what I needed. "
Theresa 1-night trip
Posted 1 day ago
Hampton Inn & Suites St. Charles Old Town Area

Hotels near other Historic Main Street attractions

Lewis & Clark festival
Photo by HA
Open Photo by HA

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.
See properties
trestle on Katy Trail in Missouri over Auxvasse Creek near Mokane - 237 mile bike trail stretching across most of the state of Missouri converted from abandoned railroad

Katy Trail

4.6/5 (53 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 89 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Other good options close by include Country Inn & Suites by Radisson, St. Charles Historic District and Best Western Plus The Charles Hotel.
How many hotels are there near Historic Main Street?
Expedia has 89 hotels and other accommodations within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.
Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?
For more information about rescheduling or cancelling your stay near Historic Main Street, click here.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Explore a world of travel with Expedia