Find Boutique Hotels in Florence, SC

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Check availability on Florence Boutique Hotels

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11
No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2209)
"Breakfast was great, room very clean ."
United States
Leann
The price is NT$2,659
NT$2,978 total
includes taxes & fees
Jan 11 - 2026/1/12
Park Inn by Radisson Florence, SC
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1174)
"Great location, friendly staff. "
United States
Defelicio
The price is NT$3,073
NT$3,441 total
includes taxes & fees
Jan 11 - 2026/1/12
Comfort Inn & Suites Florence Center Area
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2518)
"Great room and staff."
United States
LEE
The price is NT$1,980
NT$2,218 total
includes taxes & fees
Dec 28 - Dec 29
Howard Johnson by Wyndham Florence
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (534)
"Everything great "
Canada
Caroline
The price is NT$3,521
NT$3,837 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1003)
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is NT$3,143
NT$3,521 total
includes taxes & fees
Jan 5 - 2026/1/6
Hyatt Place Florence Downtown
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1003)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is NT$3,583
NT$4,014 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (29)
"Friendly staff and clean environment "
United States
john
The price is NT$3,042
NT$3,531 total
includes taxes & fees
Jan 6 - 2026/1/7
Spark by Hilton Florence North I-95, SC
Outdoor pool
Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG

Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG

Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
2.5 star property
Camden
8.4 out of 10, Very Good, (696)
"The staff at check in was friendly & professional. Breakfast was excellent."
United States
Steve
The price is NT$3,521
NT$3,943 total
includes taxes & fees
Jan 2 - 2026/1/3
Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (823)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is NT$3,601
NT$4,033 total
includes taxes & fees
Jan 7 - 2026/1/8
Hampton Inn & Suites Florence-North-I-95
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1004)
"Very good breakfast & convenient location"
United States
Diedre
The price is NT$3,458
NT$3,873 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

10/10 Excellent
"Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return. "
Holt 1-night trip
Posted 4 days ago
Hotel Florence, Tapestry Collection by Hilton

Frequently asked questions

What's there to see and do in Florence?
The shopping and restaurants are just some of the things to enjoy while you're in the area. Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center are some of the local sights worth visiting. While you're here, you might also like to explore more of the area and take in additional sights like Magnolia Mall, Florence Veterans Park, and Florence Civic Center.
What kind of weather should I plan for when I travel to Florence?
Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's the best way to get to my boutique hotel in Florence?
You have a few options for getting to Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. If you want to explore the larger area, hop on a train at Florence Station.

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