A serene lake with trees reflecting in the water, surrounded by a forest of tall, slender trees with autumn foliage.

Search Hotels in Orangeburg County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in Orangeburg County

Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines
HotelsHotels

Santee

Santee

Check prices for these dates

This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Orangeburg County hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,007 reviews)
"Property was clean and the breakfast was delicious would stay there again."
United States
Melissa
The price is NT$4,105
NT$4,557 total
includes taxes & fees
Sep 15 - Sep 16
Fairfield Inn & Suites by Marriott Santee
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,486 reviews)
"Very quiet, dog friendly, clean, breakfast included."
United States
Yomerys
The price is NT$2,529
NT$2,807 total
includes taxes & fees
Sep 17 - Sep 18
Baymont by Wyndham Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

3. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (938 reviews)
"Quick stay, hotel was clean and safe. Staff was super helpful and friendly."
United States
Vicky L
The price is NT$3,091
NT$3,431 total
includes taxes & fees
Sep 13 - Sep 14
Tru By Hilton Santee
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,004 reviews)
"My stay was comfortable and awesome I will be visiting again"
United States
TaNikka
The price is NT$3,091
NT$3,431 total
includes taxes & fees
Sep 7 - Sep 8
Spark by Hilton Orangeburg
A hotel entrance with a sign reading "Best Western PLISS."

5. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,005 reviews)
"Breakfast was good, staff very helpful."
United States
Bonnie
The price is NT$3,501
NT$3,886 total
includes taxes & fees
Sep 20 - Sep 21
Best Western Plus Santee Inn
A self-service kiosk with a beverage cooler, microwave, and various food items.

6. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,002 reviews)
"great hotel"
Canada
Andrew
The price is NT$3,611
NT$4,008 total
includes taxes & fees
Sep 15 - Sep 16
Tru by Hilton Orangeburg
A water park with a pool, slides, and umbrellas.

7. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,001 reviews)
"I stay here all the time when traveling with my dog. This place is super clean and the staff is excellent."
United States
Dennis
The price is NT$3,326
NT$3,692 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Santee by IHG
A tent with a view of a lake and boats, a wooden chair, and a potted plant.

8. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (98 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
The price is NT$2,591
NT$2,971 total
includes taxes & fees
Sep 2 - Sep 3
Bells Marina & Resort
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

9. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,001 reviews)
"Was a good place to stay"
United States
santa
The price is NT$3,204
NT$3,557 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn & Suites Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

10. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
"The room was clean, bed was comfortable, and staff was kind! It was a great stopping point on our way to Florida."
United States
Cameron
The price is NT$3,889
NT$4,317 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn Santee-I-95
A breakfast bar with pastries, fruits, and a vase with flowers.

11. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,002 reviews)
"The place was nice and clean"
United States
Arsenio
The price is NT$2,502
NT$2,778 total
includes taxes & fees
Sep 2 - Sep 3
Travelodge by Wyndham Orangeburg
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

12. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (697 reviews)
"The room was clean and comfortable"
United States
Mazzie
The price is NT$1,885
NT$2,092 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Orangeburg
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

13. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (584 reviews)
"It was very clean-might need a few updates to the bathroom tho."
United States
Clara
The price is NT$1,723
NT$2,088 total
includes taxes & fees
Sep 21 - Sep 22
Quality Inn & Suites Santee I-95
A modern hotel lobby with a green ceiling, a grey sofa, a patterned ottoman, a wooden bench, and a chair with a geometric throw.

14. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (853 reviews)
"Helpful staff, great breakfast buffet"
United States
Jenelyn
The price is NT$3,706
NT$4,114 total
includes taxes & fees
Sep 5 - Sep 6
Holiday Inn Express & Suites Orangeburg by IHG
A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

15. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (821 reviews)
"Amazing hotel. Always my go to whenever I am staying in Orangeburg. Highly recommended!"
United States
Percy
The price is NT$3,204
NT$3,557 total
includes taxes & fees
Sep 2 - Sep 3
Fairfield Inn by Marriott Orangeburg
A hotel room with a bed, a desk, a chair, a sofa, and a table.

16. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
5.8 out of 10, (1,003 reviews)
"Older Hotel dated yeah it was comfortable and convenient"
United States
Stephan J.
The price is NT$1,939
NT$2,152 total
includes taxes & fees
Sep 20 - Sep 21
Baymont by Wyndham Orangeburg North
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

17. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (812 reviews)
"Great Place to Stay!"
United States
Henrietta
The price is NT$3,457
NT$3,837 total
includes taxes & fees
Sep 7 - Sep 8
SpringHill Suites by Marriott Orangeburg
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

18. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (839 reviews)
"One of the cleanest hotels we’ve ever stayed in!"
United States
JORDAN
The price is NT$4,130
NT$4,584 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn & Suites Orangeburg

19. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (590 reviews)
"The price rate was great"
United States
Stevenson
The price is NT$2,130
NT$2,364 total
includes taxes & fees
Sep 27 - Sep 28
Ramada by Wyndham Santee I-95
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

20. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (772 reviews)
"The staff was very helpful and respectful."
United States
Mark
The price is NT$2,027
NT$2,250 total
includes taxes & fees
Sep 2 - Sep 3
Travelodge by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Orangeburg County Hotel Reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
"Room clean and decently organized by providing sufficient outlets near the beds to power up your electronic devices. The breakfast was a plus."
Alvin 1-night trip
Posted 4 hours ago
Baymont by Wyndham Santee

Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from NT$2,088 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at NT$2,088 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels!

Explore a world of travel with Expedia