Find hotels in Santee, SC from NT$1,921

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Compare 305 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (624)
"Nice place to stay"
Canada
Tanya
The price is NT$2,981
NT$3,309 total
includes taxes & fees
Dec 14 - Dec 15
Tru By Hilton Santee

Hampton Inn Santee-I-95

2.5 star property
Santee
9.6 out of 10, Exceptional, (1001)
"Breakfast was really good"
United States
Vinicius
The price is NT$3,508
NT$3,893 total
includes taxes & fees
Dec 14 - Dec 15
Hampton Inn Santee-I-95

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1405)
"The best stay"
United States
Terez
The price is NT$2,505
NT$2,781 total
includes taxes & fees
Dec 8 - Dec 9
Baymont by Wyndham Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1001)
"Very welcoming, hotel has a clean and friendly presentation."
Canada
VALERIE AND JOHN
The price is NT$3,789
NT$4,206 total
includes taxes & fees
Dec 14 - Dec 15
Fairfield Inn & Suites by Marriott Santee

Comfort Inn & Suites Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1010)
"Close to the highway with a safe location."
United States
Benjamin
The price is NT$3,096
NT$3,436 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

2.0 star property
Santee
7.0 out of 10, Good, (673)
"Breakfast could be a little better. Room was okay."
United States
Roger
The price is NT$1,942
NT$2,155 total
includes taxes & fees
Dec 8 - Dec 9
Travelodge by Wyndham Santee

Holiday Inn Santee by IHG

3.0 star property
Santee
8.2 out of 10, Very Good, (970)
"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is NT$3,491
NT$3,875 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Santee by IHG

Best Western Plus Santee Inn

2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is NT$3,700
NT$4,107 total
includes taxes & fees
Jan 1 - 2026/1/2
Best Western Plus Santee Inn

Quality Inn & Suites

2.5 star property
Santee
6.0 out of 10, (452)
"Great place. Excellent people. Great service"
United States
Jesse
The price is NT$1,704
NT$2,065 total
includes taxes & fees
Dec 10 - Dec 11
Quality Inn & Suites

Ramada by Wyndham Santee I-95

2.0 star property
Santee
6.2 out of 10, (541)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is NT$2,440
NT$2,708 total
includes taxes & fees
Dec 21 - Dec 22
Ramada by Wyndham Santee I-95

Red Roof Inn Santee

2.0 star property
Santee
6.6 out of 10, (637)
"It's a good stop for the price "
United States
Martin
The price is NT$2,197
NT$2,439 total
includes taxes & fees
Dec 14 - Dec 15
Red Roof Inn Santee

Super 8 by Wyndham Santee

2.0 star property
Santee
6.8 out of 10, (438)
"Clean room and felt safe and secured. "
United States
Kelly
The price is NT$2,349
NT$2,607 total
includes taxes & fees
Dec 7 - Dec 8
Super 8 by Wyndham Santee

Econo Lodge

2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
The price is NT$1,978
NT$2,196 total
includes taxes & fees
Jan 4 - 2026/1/5
Econo Lodge

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1001)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is NT$3,232
NT$3,587 total
includes taxes & fees
Dec 10 - Dec 11
Tru by Hilton Orangeburg

Comfort Inn & Suites Orangeburg

2.5 star property
Orangeburg
8.0 out of 10, Very Good, (543)
"Would recommend this hotel for out of town guest with no hesitation. "
United States
Yvette
The price is NT$2,972
NT$3,299 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Orangeburg

Spark by Hilton Orangeburg

2.5 star property
Orangeburg
7.8 out of 10, Good, (1000)
"Clean, quiet, nice place for an overnight stay"
United States
Joseph
The price is NT$2,731
NT$3,031 total
includes taxes & fees
Dec 14 - Dec 15
Spark by Hilton Orangeburg

SureStay Hotel by Best Western Manning

2.5 star property
Manning
8.6 out of 10, Excellent, (1011)
"Staff was very courteous "
United States
Dayshia
The price is NT$2,787
NT$3,094 total
includes taxes & fees
Dec 8 - Dec 9
SureStay Hotel by Best Western Manning

Days Inn by Wyndham St George

2.5 star property
St. George
7.6 out of 10, Good, (1002)
"Helpful folks at check in and super clean room. "
United States
Peter
The price is NT$2,104
NT$2,335 total
includes taxes & fees
Jan 4 - 2026/1/5
Days Inn by Wyndham St George

Fairfield Inn by Marriott Orangeburg

2.5 star property
Orangeburg
8.4 out of 10, Very Good, (684)
"Enjoyed my stay for homecoming go Bulldogs ! "
United States
David
The price is NT$2,631
NT$2,920 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn by Marriott Orangeburg

Sleep Inn Orangeburg

2.5 star property
Orangeburg
7.6 out of 10, Good, (379)
"Courteous staff"
United States
David
The price is NT$2,362
NT$2,622 total
includes taxes & fees
Dec 26 - Dec 27
Sleep Inn Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Hotels in Santee with star-rating

Find out more about Santee

Top reasons to visit Santee

  • Outdoor Adventures: Santee offers stunning lakes and scenic parks, perfect for nature lovers and outdoor activities like hiking and fishing.
  • World-Class Golf: Experience exceptional golf courses that cater to enthusiasts, providing a memorable golfing getaway.
  • Serene Fishing Opportunities: Enjoy fishing in serene waters, especially for striped bass, making it a perfect spot for anglers.
  • Charming Accommodations: A variety of hotels and inns provide comfortable stays, accommodating diverse traveler needs.
  • Southern Hospitality: Explore the friendly neighborhoods and embrace the warm, welcoming atmosphere of Santee.

Find great hotels in and around Santee

Discover a variety of hotel accommodations in Santee, South Carolina, perfect for every traveler. Whether you're looking for pet-friendly options, business facilities, or a welcoming environment for LGBTQIA guests, Santee has it all. From cozy inns to well-equipped suites, you’ll find the best hotels that cater to your needs, ensuring a comfortable and enjoyable stay in this charming area.

  • Baymont by Wyndham Santee: Emphasizing comfort and convenience, Baymont by Wyndham Santee caters to both business travelers and pet owners. This welcoming hotel stands out with its pet-friendly policy, allowing dogs and cats, making it an ideal choice for those who wish to travel with their furry friends. The property offers essential amenities such as complimentary breakfast, free Wi-Fi, and a fitness center, ensuring a pleasant stay for all guests. Its convenient location in Santee provides easy access to local attractions, making it a practical base for exploring the area.
  • Fairfield Inn by Marriott Orangeburg: Located 30.6km from Santee, Fairfield Inn by Marriott Orangeburg is a vibrant and inclusive hotel perfect for LGBTQIA travelers and those on business trips. This property is known for its warm atmosphere and commitment to welcoming all guests. Offering modern rooms equipped with free Wi-Fi, a business center, and a complimentary breakfast, it ensures a comfortable and productive stay. Its affiliation with LGBTQI travel guides underscores its dedication to diversity, making it a fantastic choice for travelers seeking a supportive environment.
  • Comfort Inn & Suites Santee: Designed with families in mind, Comfort Inn & Suites Santee provides a warm and inviting atmosphere for parents and children alike. The hotel features spacious rooms, a complimentary breakfast, and family-friendly amenities such as free cribs for infants. With its prime location in Santee, families can easily explore local attractions while enjoying the relaxing comforts of home. Guests appreciate the attentive service and the thoughtful touches that make their stay enjoyable and memorable.

Where to stay near Santee

Discover the charm of Santee, South Carolina, where outdoor adventures and scenic beauty await. Enjoy serene waters perfect for fishing or boating, and experience the friendly vibe of this budget-friendly destination. With romantic spots and family-friendly excursions, Santee offers a unique blend of relaxation and excitement. Explore nearby neighborhoods rich in Southern hospitality and indulge in value golf experiences that make your stay truly memorable.

  • Vance: Nestled only 8.0km from Santee, Vance is a charming city that draws visitors seeking a romantic outdoor getaway. The travel experience here is accentuated by its stunning scenery, with seasonal peaks in traveler arrivals during March to April and July. Vance is perfect for those who love golf, with several courses nearby, and offers access to recreational areas that invite exploration. Local landmarks like serene lakes, national state parks, and beautiful beaches highlight the area's natural beauty, making it an ideal destination for nature enthusiasts.
  • Summerton: Located 17.7km from Santee, Summerton boasts a welcoming atmosphere for travelers throughout the year. With peak visitation from March to April and July, this city is a haven for outdoor lovers and those seeking picturesque views. Visitors can enjoy various recreational activities and golf courses, while local attractions such as lakes, water features, and islands provide unique experiences. The town's scenic charm and romantic ambiance make it a fantastic spot for a peaceful retreat.
  • Elloree: Just 9.7km away from Santee, Elloree is a delightful city that offers a year-round inviting experience for travelers. With visitor peaks in March, July, and September, Elloree is known for its outdoor scenery and romantic escapades. Golf enthusiasts will find plenty of courses to choose from, and the nearby lakes and national parks promise unforgettable adventures. The combination of recreation and natural beauty makes Elloree an appealing destination for a tranquil getaway.

Things to do in and around Santee

Santee, South Carolina, is perfect for outdoor and romantic getaways, offering stunning scenery and a variety of activities. Visitors can enjoy recreational areas, world-class golf courses, and opportunities for fishing, particularly for striped bass. For a well-rounded experience, consider exploring the local nightlife and planning a golf vacation stay or a day trip to soak in the natural beauty and charm of this delightful destination.

Shopping

Santee offers a unique shopping experience at local stores. For gifts and souvenirs, visit Bee City, located 48.3km away, or check out Pocalla Crossing Shopping Center, 43.5km from Santee, which has a family-friendly vibe with various shops to explore.

Recreation

Experience a round of golf at Santee Cooper Country Club, surrounded by lush landscapes and a vibrant outdoor atmosphere. For tranquility, visit Santee National Wildlife Refuge, where you can unwind in nature. Alternatively, enjoy recreational activities at Patriots Sports Plex, offering a relaxing environment to rejuvenate.

Adventure

Santee State Park offers hiking trails, fishing spots, and stunning views of Lake Marion. For a dose of excitement, try water sports such as kayaking and jet skiing. Explore the park's diverse wildlife while enjoying serene picnics amidst nature’s beauty.

Nightlife

Santee's nightlife offers a relaxed vibe with options like the popular Santee Cooper Resort Bar & Grill for casual drinks and live music. For a more laid-back experience, check out the local diners and taverns where you can enjoy good food and friendly conversations under the stars.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santee

To save money on your trip to Santee, South Carolina, take advantage of the free entry to attractions like Taw Caw Creek. The best time to visit is from December to February, when accommodation prices drop, with Mondays being the cheapest days to stay. Use Expedia's search tool to compare hotel rates and find budget-friendly options, including eco-certified hotels. Consider booking a package that combines your hotel, flights, and activities for additional savings. For transportation, explore options like biking or using the bus for an economical way to get around.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred destination, and additional preferences. You can arrange your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your search by hotel category; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotel options that you can reserve.
  • Consider bundling your trip: You can save money by booking an Expedia package that combines your hotel stay in Santee with flights and activities.

Find the best attractions in and around Santee

Santee, South Carolina, is perfect for a romantic outdoor getaway, featuring beautiful lakes and scenic national parks. Visitors can explore Santee State Park, a prime spot for enjoying nature and outdoor activities. With its picturesque landscapes and opportunities for beach experiences, Santee offers a delightful escape for travelers seeking relaxation and adventure alike.

  • Santee State Park: Experience the beauty of nature in Santee State Park, where you can enjoy scenic views, hiking trails, and various outdoor adventures. It's a perfect spot for camping, fishing, and boating, surrounded by lush greenery and serene waters.
  • Taw Caw Creek: Just 14.5km from Santee, Taw Caw Creek offers a picturesque lake with sandy beaches, making it an ideal romantic getaway. Enjoy water activities, picnicking, or simply soaking in the stunning scenery with your loved one.
  • Santee Indian Mound and Fort Watson Site: Located 6.4km away, this cultural site provides a glimpse into the history of the Native American tribes and early colonial forts. Explore the historical significance and enjoy the peaceful surroundings of this unique landmark.

Best time to go to Santee

The best time to visit Santee can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santee falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Santee falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighAverage
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighSlightly High
May72.0°F (22.2°C)Light RainMostly SunnyAverageSlightly High
June78.6°F (25.9°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighAverage
August79.9°F (26.6°C)Light RainMostly SunnyAverageAverage
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowSlightly High
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Santee

When planning your trip to Santee, South Carolina, you have two major airports to consider. Charleston International Airport (CHS) is located 78.9km away, with excellent hotel options like The Charleston Place, The Dewberry Charleston, and Hotel Bennett, all 14.5km from the airport, offering shuttle services. Alternatively, Columbia Metropolitan Airport (CAE) is also 78.9km from Santee, featuring hotels such as Graduate by Hilton Columbia and Doubletree by Hilton Columbia, both within 6 to 11.3km, providing convenient access. Each airport ensures a comfortable stay with nearby accommodations and transportation options to make your visit enjoyable.

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals in Santee?
Wyndham Vacation Resorts Lake Marion: Visitors give good reviews to this Santee vacation home rental, which is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher, and a stovetop. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about updating your trip to Santee or cancelling it, click here.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Tru By Hilton Santee is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Other good choices for you and your pet's trip include Baymont by Wyndham Santee and Holiday Inn Santee by IHG. See more pet-friendly hotel accommodations in Santee.
Where is the best place to stay near Santee State Park?
Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.
What about the best place to stay close to Santee Outlets?
One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites is another choice with an onsite pool. View all hotels with pools in Santee.
What's the best place to stay near Columbia Metropolitan Airport (CAE)?
Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 127 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. A couple of additional sights to add to your agenda are Lake Marion and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.

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