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Cape Girardeau County
Missouri
United States of America
Hotels
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Top Cities in Cape Girardeau County

A calm body of water, a sandy beach, and a forested area in the distance.

A river, a large white building, and a cityscape.

A tree with white blossoms in a grassy area surrounded by trees.

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Our top choices for Cape Girardeau County hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property

Cape Girardeau

9.6 out of 10, Exceptional, (1,004 reviews)

9.6/10

Exceptional

(1,004 reviews)

"Great stay! Hot tub was enjoyable and the staff was super friendly!"

"Great stay! Hot tub was enjoyable and the staff was super friendly!"

United States

Chris

The price is NT$3,255

NT$3,255

NT$3,672 total

includes taxes & fees

Oct 27 - Oct 28

Drury Plaza Hotel Cape Girardeau Conference Center

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

2. The Riverview

4.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (690 reviews)

9.4/10

Exceptional

(690 reviews)

"Clean, quiet, comfortable room. Very comfortable beds."

"Clean, quiet, comfortable room. Very comfortable beds."

United States

Renee

The price is NT$3,720

NT$3,720

NT$4,197 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

3. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property

Cape Girardeau

9.2 out of 10, Wonderful, (1,001 reviews)

9.2/10

Wonderful

(1,001 reviews)

"Room was clean and staff was very friendly"

"Room was clean and staff was very friendly"

United States

Troy

The price is NT$2,343

NT$2,343

NT$2,643 total

includes taxes & fees

Nov 1 - Nov 2

Pear Tree Inn Cape Girardeau West

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (1,000 reviews)

9.4/10

Exceptional

(1,000 reviews)

"The food was excellent"

"The food was excellent"

United States

DENNIS

The price is NT$2,929

NT$2,929

NT$3,304 total

includes taxes & fees

Nov 1 - Nov 2

Drury Inn & Suites Cape Girardeau

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A buffet with labeled containers of turkey sausage and cookies.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property

Cape Girardeau

9.4 out of 10, Exceptional, (1,000 reviews)

9.4/10

Exceptional

(1,000 reviews)

"Perfect location, beds were awesome & staff were friendly & accommodating!"

"Perfect location, beds were awesome & staff were friendly & accommodating!"

United States

Rebecca

The price is NT$3,092

NT$3,092

NT$3,519 total

includes taxes & fees

Nov 22 - Nov 23

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property

Jackson

9.0 out of 10, Wonderful, (881 reviews)

9.0/10

Wonderful

(881 reviews)

"Breakfast was good."

"Breakfast was good."

United States

J

The price is NT$2,601

NT$2,601

NT$2,815 total

includes taxes & fees

Nov 1 - Nov 2

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

7. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property

Jackson

9.6 out of 10, Exceptional, (1,002 reviews)

9.6/10

Exceptional

(1,002 reviews)

"Clean room affordable and great breakfast I would definitely go back!"

"Clean room affordable and great breakfast I would definitely go back!"

United States

Lyn

The price is NT$2,604

NT$2,604

NT$2,753 total

includes taxes & fees

Oct 28 - Oct 29

Drury Inn & Suites Jackson MO

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

8. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2.5 star property

Cape Girardeau

7.0 out of 10, Good, (812 reviews)

7.0/10

Good

(812 reviews)

"Clean rooms, nice staff"

"Clean rooms, nice staff"

United States

Dayanita

The price is NT$1,933

NT$1,933

NT$2,181 total

includes taxes & fees

Nov 1 - Nov 2

Quality Inn Cape Girardeau North

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel lobby with a reception desk, seating area, and a large glass door entrance.

A hotel room with a kitchenette, a bed, a desk, and a TV.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

9. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property

Cape Girardeau

8.0 out of 10, Very good, (1,002 reviews)

8.0/10

Very good

(1,002 reviews)

"Nice clean room"

"Nice clean room"

United States

James

The price is NT$2,311

NT$2,311

NT$2,786 total

includes taxes & fees

Nov 22 - Nov 23

Candlewood Suites Cape Girardeau by IHG

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

10. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (236 reviews)

9.4/10

Exceptional

(236 reviews)

"Great hotel…!!"

"Great hotel…!!"

United States

Carlos

The price is NT$3,292

NT$3,292

NT$3,714 total

includes taxes & fees

Oct 29 - Oct 30

Fairfield Inn & Suites by Marriott Cape Girardeau

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

11. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 star property

Cape Girardeau

9.6 out of 10, Exceptional, (195 reviews)

9.6/10

Exceptional

(195 reviews)

"Had a great stay friendly staff very clean facilities!"

"Had a great stay friendly staff very clean facilities!"

United States

Shannon

The price is NT$2,909

NT$2,909

NT$3,311 total

includes taxes & fees

Nov 1 - Nov 2

Tru By Hilton Cape Girardeau

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A lobby with seating areas, a reception desk, and a bar.

12. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property

Cape Girardeau

9.6 out of 10, Exceptional, (554 reviews)

9.6/10

Exceptional

(554 reviews)

"Perfect place and location for our girls trip. The staff was excellent!"

"Perfect place and location for our girls trip. The staff was excellent!"

United States

Kristin

The price is NT$3,569

NT$3,569

NT$4,044 total

includes taxes & fees

Nov 1 - Nov 2

Courtyard by Marriott Cape Girardeau Downtown

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A bathroom with a marble wall and a white bathtub.

13. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property

Cape Girardeau

6.2 out of 10, (243 reviews)

6.2/10

(243 reviews)

"Clean affordable and friendly staff"

"Clean affordable and friendly staff"

United States

Hope

The price is NT$2,278

NT$2,278

NT$2,662 total

includes taxes & fees

Oct 25 - Oct 26

Town House Inn Cape Giradreau

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

14. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property

Cape Girardeau

9.6 out of 10, Exceptional, (854 reviews)

9.6/10

Exceptional

(854 reviews)

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

United States

Brittany

The price is NT$3,043

NT$3,043

NT$3,433 total

includes taxes & fees

Nov 15 - Nov 16

Hampton Inn Cape Girardeau I 55 East

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property

Jackson

8.0 out of 10, Very good, (785 reviews)

8.0/10

Very good

(785 reviews)

"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"

"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"

United States

Jeff

The price is NT$2,462

NT$2,462

NT$2,665 total

includes taxes & fees

Nov 12 - Nov 13

Comfort Suites Jackson-Cape Girardeau

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

Exterior

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

16. Town House Inn

2.5 star property

Jackson

7.6 out of 10, Good, (449 reviews)

7.6/10

Good

(449 reviews)

"Great owners "

"Great owners "

United States

Jennifer

The price is NT$2,320

NT$2,320

NT$2,511 total

includes taxes & fees

Oct 25 - Oct 26

A rustic wooden cabin with a porch, outdoor seating, and a view of a lush green landscape.

A rustic cabin interior with wooden beams, a green door, and a cozy seating area with patterned cushions and a round coffee table.

A log cabin room with a bed, curtains, a lamp, and a green door.

A rustic kitchen with wooden walls, a large window, and a vintage stove.

17. Private Getaway on 270 Acres w/ Lake: Swim & Canoe

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

2.0 star property

Advance

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

A spacious living area with a sofa, a coffee table, and a TV.

A modern kitchen with white cabinets, a central island, and a dining area with a wooden table and chairs.

A two-story house with a garage, a brick section on the side, and a clear sky.

A spacious living area with a dining table, chairs, and a ceiling fan.

18. Deck & Large Yard! Family Haven in Cape Girardeau

Deck & Large Yard! Family Haven in Cape Girardeau

3.0 star property

Cape Girardeau

Deck & Large Yard! Family Haven in Cape Girardeau

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Cape Girardeau County Hotel Reviews

The Riverview

The Riverview

10/10 Excellent

"Clean room, everything you need was right on the property"

Angie 2-night trip

Posted 3 hours ago

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent

"We want to thank all the staff for making our stay wonderful. The check in an out, room, food (both breakfast and dinner), pool, dining area and popcorn was great. We always enjoy staying here. Stay blessed always!"

Ashley 1-night trip

Posted 6 hours ago

Drury Inn & Suites Jackson MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Very clean. Food and drinks were excellent. Staff was very helpful."

Sally 1-night trip

Posted 1 day ago

Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"I did not realize this was a Drury property until we got there, but I love Drury. Clean rooms, and very nice amenities. The staff was so friendly. We enjoyed our stay very much!"

Christina 1-night trip

Posted 1 day ago

Pear Tree Inn Cape Girardeau West

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

8/10 Good

"Staff was awesome and very helpful. Place was very clean."

Christina 1-night trip

Posted 1 day ago

Super 8 by Wyndham Perryville

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"LOVE the double bench available for 2 suitcases! Top notch, KUDOS on that little thing that meant so much to us as seniors. Breakfast was good, rooms were clean, restaurant was nice. An overall exceptional experience. This stay moved Holiday Inn Express up a few notches on my list."

Denise 1-night trip

Posted 2 days ago

Holiday Inn Express & Suites Perryville by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Quick clean and very helpful"

Kristina 1-night trip

Posted 2 days ago

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

10/10 Excellent

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

Brittany 1-night trip

Posted 4 days ago

Hampton Inn Cape Girardeau I 55 East

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good

"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."

Jaime 1-night trip

Posted 5 days ago

Town House Inn Cape Giradreau

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Flights from Marsa Matruh (MUH) to Cape Girardeau (CGI)
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Flights from Boise (BOI) to Cape Girardeau (CGI)
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Flights from Gambell (GAM) to Cape Girardeau (CGI)
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