Find Resorts & Hotels with Spas in Cross Key Waterways, FL

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Check prices for these dates

Tonight
Nov 4 - Nov 5
Tomorrow
Nov 5 - Nov 6
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Cross Key Waterways hotels with a spa

A hotel room with a bed, a dresser, a mirror, and a nightstand.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,560 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is NT$7,136
NT$9,331 total
includes taxes & fees
Nov 29 - Nov 30
Reefhouse Resort & Marina
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is NT$8,569
NT$11,437 total
includes taxes & fees
Nov 29 - Nov 30
Playa Largo Resort & Spa, Autograph Collection
A beach with palm trees, a thatched-roof structure, and kayaks.

3. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (366 reviews)
  • cleanliness
    Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
The price is NT$9,061
NT$11,111 total
includes taxes & fees
Nov 10 - Nov 11
Kona Kai Resort and Gallery - Adults Only
A spacious interior with a high ceiling, large windows, and a central light fixture.

4. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.8 out of 10, Excellent, (1,196 reviews)
The price is NT$8,790
NT$11,685 total
includes taxes & fees
Nov 15 - Nov 16
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
9.6 out of 10, Exceptional, (4 reviews)
  • cleanliness
    Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
The price is NT$23,257
NT$26,164 total
includes taxes & fees
Nov 5 - Nov 6
Premium Floating Bungalow by Stay Ombi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Cross Key Waterways

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
Reefhouse Resort & Marina
4.5 star property
9.2
Wonderful
1,560 reviews
View
A beach with palm trees, a thatched-roof structure, and kayaks.
Kona Kai Resort and Gallery - Adults Only
2.5 star property
9.8
Exceptional
366 reviews
View
A beach with lounge chairs and a pier extending into the water.
Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
8.8
Excellent
1,196 reviews
View
An aerial view of a resort with a large pool, palm trees, and a beach.
Playa Largo Resort & Spa, Autograph Collection
4.5 star property
9.0
Wonderful
1,001 reviews
View
A floating house with a thatched roof, large sliding glass doors, and a wooden deck with a chair.
Premium Floating Bungalow by Stay Ombi
3.5 star property
9.6
Exceptional
4 reviews
View

Top Cross Key Waterways Hotel Reviews

A hotel room with a bed, a dresser, a mirror, and a nightstand.
Reefhouse Resort & Marina

Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo

10/10 Excellent

This place was beautiful! A little slice of paradise! We found this gem and definitely will be back again. Everything was great, clean, the food was amazing!
United States
Deb
Reviewed May 20, 2025
Reefhouse Resort & Marina

Frequently Asked Questions

Looking for a spa hotel in Cross Key Waterways?

Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your vacation.

What's there to see and do in Cross Key Waterways?

Enjoy Cross Key Waterways with a stop at MarineLab Undersea Laboratory, Caribbean Club Bar, and John Pennekamp Coral Reef State Park. If you have some spare time during your trip, you might want to check out Jacob's Aquatic Center and Jimmy Johnson's Big Chill.

What is a Cross Key Waterways spa hotel?

Spa hotels in Cross Key Waterways provide lodging and have a full on-site spa which offers services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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