Find Luxury Hotels in Cairo, IL

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Check availability on Cairo Luxury Hotels

Top Cairo Luxury Hotels

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Recommended hotels in Cairo

Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (260)
"Stay here almost weekly. Very quiet, not around anything other than a dollar general which is good. Just a bit pricey for a night. "
The price is NT$2,189
NT$2,430 total
includes taxes & fees
Jul 27 - Jul 28
Quality Inn Cairo I-57
La Center Motel
Basic Double Room | 1 bedroom, free WiFi

La Center Motel

2.0 star property
7.8 out of 10, Good, (14)
"Front desk staff was amazing. Room was comfy and quiet! Clean! Husband and I needed a place to crash on our long ride home and this motel did not disappoint!"
La Center Motel
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is NT$1,928
NT$2,139 total
includes taxes & fees
Jul 14 - Jul 15
Eagle Inn Charleston
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (572)
"A great surprise in Owasso! Great price and excellent room. So impressed. "
The price is NT$1,893
NT$2,101 total
includes taxes & fees
Jul 27 - Jul 28
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (389)
"Very friendly and accommodating "
The price is NT$2,027
NT$2,250 total
includes taxes & fees
Jul 27 - Jul 28
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Cairo?
Let Expedia help you arrange your flight to Cairo, IL (CIR-Cairo Regional) airport or Paducah, KY (PAH-Barkley Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Cairo has to offer. Cairo has some interesting things to see and do including Mississippi River and Fort Defiance State Park, so you might want to take in the local sights during your visit.
When can I expect good weather in Cairo?
Planning for the weather is an important factor for making your trip to Cairo a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What's there to see and do in Cairo?
Enjoy all that Cairo has to offer and visit Mississippi River, Fort Defiance State Park, and Columbus-Belmont State Park. If you have spare time during your trip, you might want to make a stop at Ullin City Hall and Ballard Wildlife Management Area.