Cairo Ohio River Bridge traversing over the Ohio River at sunset

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Check availability on Cairo Family Hotels

Our top choices for Cairo family-friendly hotels

Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (288 reviews)
  • cleanliness
    Quiet family comfort with free breakfast and modern amenities along the Mississippi River makes this hotel perfect for stress-free trips.
The price is NT$2,277
NT$2,527 total
includes taxes & fees
Jul 11 - Jul 12
Quality Inn Cairo I-57
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (416 reviews)
  • cleanliness
    Kids stay active and happy with free activities, family-friendly rooms, and morning meals at this welcoming Charleston hotel.
The price is NT$2,367
NT$2,626 total
includes taxes & fees
Jun 17 - Jun 18
The Riverstone Hotel Charleston-Sikeston
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (641 reviews)
  • cleanliness
    Unleash family fun in Charleston with premium TV channels, pay movies, and free cribs, all while friendly staff elevate your stay.
The price is NT$1,877
NT$2,084 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at family-friendly hotels in Cairo

Breakfast included
Pool

Top Cairo Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

8/10 Good
"The outside of the hotel needs some work The breakfast needed more than instant oatmeal for breakfast. Muffins wrapped separately would have been nice. Banana along with the apples. Cold cereals in little bowls. Just anything more than what they had."
Catherine Ann 1-night trip
Posted 5 days ago
Super 8 by Wyndham Charleston/Sikeston East MO

Frequently asked questions

What's Cairo like for family-friendly vacations?
You might want to consider the historic destination of Cairo if you've been thinking about a trip for the whole family. The entertainment, restaurants, and libraries are just a few things that make this an attractive spot for a family vacation. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is the closest airport, or Paducah, KY (PAH-Barkley Regional), which is located 22.9 mi (36.8 km) from the city center.
What's the best hotel for a family vacation to Cairo?
Quality Inn Cairo I-57 is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What's there to see and do with your family in Cairo?
While you and the family are vacationing in Cairo, you might want to get outside and enjoy the great outdoors at spots such as Mississippi River, Ohio River Valley, and Shawnee National Forest. Make sure you have time to check out activities like Ohio River and Fort Defiance State Park.

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