Find hotels in Barrio de Santiago, Mérida

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Barrio de Santiago hotels

Casona 61 Boutique Hotel

Casona 61 Boutique Hotel
3.5 star property
Barrio de Santiago
8.8 out of 10, Excellent, (364)
"The staff was excellent, the rooms were clean, and there is a lot to do within walking distance"
United States
Evan Robert
Casona 61 Boutique Hotel

Kapsul Express Mérida

Kapsul Express Mérida
2.0 star property
Barrio de Santiago
8.8 out of 10, Excellent, (65)
"It is perfect for a short stay. It really does the job for the price paid! I went twice on this trip."
Canada
Anthony
The price is NT$849
NT$1,028 total
includes taxes & fees
Dec 19 - Dec 20
Kapsul Express Mérida

Art 57 Hotel - Adults Only

Art 57 Hotel - Adults Only
3.5 star property
Barrio de Santiago
8.4 out of 10, Very Good, (758)
"Clean room, great staff"
United States
Andre
Art 57 Hotel - Adults Only

The Diplomat Boutique Hotel

The Diplomat Boutique Hotel
4.0 star property
Barrio de Santiago
10.0 out of 10, Exceptional, (49)
"The property is beautiful and the staff we met were amazing. Jete made us an incredibly delicious vegan breakfast. This is my favorite hotel ever. "
United States
Nicholas
The price is NT$10,785
NT$12,996 total
includes taxes & fees
Jan 3 - 2026/1/4
The Diplomat Boutique Hotel

Hotel Unknown

Hotel Unknown
3.5 star property
Barrio de Santiago
9.2 out of 10, Wonderful, (305)
"Very cozy hotel "
United States
Marco
Hotel Unknown

Merida Santiago Hotel Boutique

Merida Santiago Hotel Boutique
4.0 star property
Barrio de Santiago
10.0 out of 10, Exceptional, (158)
"good Hotel"
Japan
YUKI
Merida Santiago Hotel Boutique

Hotel Casa Azuli

Hotel Casa Azuli
3.0 star property
Barrio de Santiago
8.8 out of 10, Excellent, (57)
"Everyone was so nice and the place was so beautiful "
United States
John
Hotel Casa Azuli

Hotel Zamna

Hotel Zamna
3.0 star property
Barrio de Santiago
9.4 out of 10, Exceptional, (178)
"Staff is super friendly and very helpful. Rooms are beautiful and clean. "
United Kingdom
Kerstin
Hotel Zamna

Kuxtal Hotel Boutique

Kuxtal Hotel Boutique
3.0 star property
Barrio de Santiago
9.6 out of 10, Exceptional, (97)
"Great place all around. "
United States
Richard
The price is NT$3,091
NT$3,725 total
includes taxes & fees
Jan 12 - 2026/1/13
Kuxtal Hotel Boutique

Casa Tunkul

Casa Tunkul
2.0 star property
Barrio de Santiago
9.8 out of 10, Exceptional, (8)
"Very good host very acomodating 👌"
United States
Jose luis
The price is NT$3,103
NT$4,275 total
includes taxes & fees
Jan 8 - 2026/1/9
Casa Tunkul

Casa Loreto 1893

Casa Loreto 1893
5.0 star property
Barrio de Santiago
9.8 out of 10, Exceptional, (78)
"Staff was incredible. Hotel Boutique one of a kind. Will be back there very soon!!"
United States
Mauricio
Casa Loreto 1893

Kunuk Hotel Boutique

Kunuk Hotel Boutique
4.5 star property
Barrio de Santiago
9.8 out of 10, Exceptional, (45)
"Clean room, great vibe, friendly staff. Not that great in the restaurant service, took too long and some items on the menu where missing. The rooms are great!"
United States
Juan
The price is NT$8,657
NT$10,432 total
includes taxes & fees
Jan 9 - 2026/1/10
Kunuk Hotel Boutique

Viva Merida Hotel Boutique

Viva Merida Hotel Boutique
3.5 star property
Barrio de Santiago
9.0 out of 10, Wonderful, (48)
"It’s too expensive for the quality of hotel. "
United States
Janie
The price is NT$3,482
NT$4,213 total
includes taxes & fees
Dec 24 - Dec 25
Viva Merida Hotel Boutique

Hotel Boutique La Casona By Kavia

Hotel Boutique La Casona By Kavia
3.5 star property
Barrio de Santiago
8.6 out of 10, Excellent, (280)
"Good clean hotel. Well situated near the Merida Granda, and you can walk to all the places of Merida from the hotel "
Canada
Kunal
The price is NT$2,247
NT$2,719 total
includes taxes & fees
Dec 19 - Dec 20
Hotel Boutique La Casona By Kavia

Hotel Ambassador Merida

Hotel Ambassador Merida
3.0 star property
Barrio de Santiago
7.8 out of 10, Good, (1000)
"Very nice hotel for the price. "
United States
Jeaneane
The price is NT$1,302
NT$1,576 total
includes taxes & fees
Dec 19 - Dec 20
Hotel Ambassador Merida

Hotel Residencial

Hotel Residencial
3.0 star property
Barrio de Santiago
8.0 out of 10, Very Good, (173)
"Have one of the best restaurants"
United States
Julio César
The price is NT$2,354
NT$2,836 total
includes taxes & fees
Jan 2 - 2026/1/3
Hotel Residencial

Hotel Embajadores

Hotel Embajadores
2.5 star property
Barrio de Santiago
7.0 out of 10, Good, (406)
"Excelente "
Mexico
Kenny
The price is NT$1,380
NT$1,663 total
includes taxes & fees
Jan 15 - 2026/1/16
Hotel Embajadores

Hotel Casa 57

Hotel Casa 57
3.0 star property
Barrio de Santiago
8.6 out of 10, Excellent, (328)
"The staff was very attentive. Great location. I would stay here again."
United States
Tomas
The price is NT$1,393
NT$1,685 total
includes taxes & fees
Dec 19 - Dec 20
Hotel Casa 57

Hotel El Cid Merida

Hotel El Cid Merida
3.0 star property
Barrio de Santiago
6.0 out of 10, (525)
"Ex"
Mexico
VALERIA
The price is NT$821
NT$994 total
includes taxes & fees
Dec 19 - Dec 20
Hotel El Cid Merida

Hacienda Xcanatun, Angsana Heritage Collection

Hacienda Xcanatun, Angsana Heritage Collection
5.0 star property
11.6 km from Barrio de Santiago
9.4 out of 10, Exceptional, (463)
"Really enjoyed our stay here."
United States
Leah
The price is NT$6,150
NT$8,025 total
includes taxes & fees
Jan 12 - 2026/1/13
Hacienda Xcanatun, Angsana Heritage Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most.

Mérida Centro

The core of the White City is a fusion of Mayan ruins, Spanish colonial churches and intriguing galleries and museums.

Chelem

A small beach in Yucatán, Mexico, this area boasts quaint houses and charming restaurants near Progreso, perfect for a relaxing coastal getaway.

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

Uxmal

Atmospheric ruins emerge from the jungle at this UNESCO site, where markets hummed with activity and Mayan priests once gazed up toward glittering constellations.

Chicxulub Puerto

Small coastal town Chicxulub Puerto lies near the center of the Chicxulub crater in Yucatán, offering a unique geological experience by the Gulf of Mexico. Discover the origin of its intriguing name, 'the devil's flea', in Yucatec Maya language.

Top Barrio de Santiago Hotel Reviews

Frequently asked questions

What is Barrio de Santiago like?
Travelers to Mérida's Barrio de Santiago neighborhood will be sure to enjoy a stay in this neighborhood. Be sure to check out Casa Frederick Catherwood and Merida English Library as part of your Barrio de Santiago travel plans.
What's the best accommodation in Barrio de Santiago?
Based on Expedia customer reviews, The Diplomat Boutique Hotel is the highest ranked property in Barrio de Santiago. This hotel offers free breakfast and an outdoor pool. Other top choices in the neighborhood include Merida Santiago Hotel Boutique and Casa Loreto 1893.
How many hotels will I find in the Barrio de Santiago area?
Expedia has 122 hotels and other accommodations in Barrio de Santiago to choose from, making this an ideal home base for exploring the greater Mérida area.
If I need to cancel my hotel reservation in Barrio de Santiago, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get top deals in Barrio de Santiago.
Where can I learn more about changing or cancelling my trip to Barrio de Santiago?
For more information about changing or cancelling your trip to Barrio de Santiago, click here.
What are the top things to see and do in Barrio de Santiago?
A few attractions you might want to check out while you're in Barrio de Santiago are Casa Frederick Catherwood and Merida English Library. Parque Zoológico del Centenario and Zoological Park of Centenario are also worth a visit when you're out sightseeing in Mérida.