Find Resorts & Hotels with Spas in Antigua Guatemala

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Antigua Guatemala Resorts & Hotels with Spas

Our top choices for Antigua Guatemala hotels with a spa

Interior
Las Camelias Inn

Las Camelias Inn

Las Camelias Inn
3.0 star property
Historic Center
8.8 out of 10, Excellent, (575)
"Very good place for my stay in Antigua. They were so helpful in storing my luggages away even after check out for a whole day for free when I went for the volcano hike. "
Canada
Joel
The price is NT$3,492
NT$4,261 total
includes taxes & fees
Jan 2 - 2026/1/3
Las Camelias Inn
Exterior
Hotel Casa Carmina

Hotel Casa Carmina

Hotel Casa Carmina
4.0 star property
Antigua Guatemala
9.0 out of 10, Wonderful, (208)
"Very nice and clean property"
Canada
Negar
The price is NT$2,183
NT$2,663 total
includes taxes & fees
Dec 24 - Dec 25
Hotel Casa Carmina
Living area
Indian Palace

Indian Palace

Indian Palace
3.0 star property
Antigua Guatemala
9.2 out of 10, Wonderful, (25)
"Beautiful view to the volcanics clean area Beautiful pool, good game room i will recommend."
United States
Estuardo
The price is NT$2,475
NT$3,019 total
includes taxes & fees
Dec 13 - Dec 14
Indian Palace
Front of property
Mestizo Cortijo

Mestizo Cortijo

Mestizo Cortijo
3.0 star property
Ciudad Vieja
9.0 out of 10, Wonderful, (92)
"Nice place to stay and enjoy Antigua Guatemala "
United States
Allan
The price is NT$3,691
NT$4,503 total
includes taxes & fees
Dec 14 - Dec 15
Mestizo Cortijo
Standard Spa Living (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo
4.5 star property
Barrio de La Concepción
9.2 out of 10, Wonderful, (1001)
"Great room, the food was awesome and the amenities are just amazing."
United States
Cesar Luis Sinclair
The price is NT$7,421
NT$9,434 total
includes taxes & fees
Jan 4 - 2026/1/5
Hotel Museo Spa Casa Santo Domingo
Sauna, hot tub, steam room, aromatherapy, hot stone massages
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa
4.5 star property
Antigua Guatemala
9.4 out of 10, Exceptional, (1000)
"Great place to stay. "
United States
tania
The price is NT$4,727
NT$5,954 total
includes taxes & fees
Dec 15 - Dec 16
Los Pasos Boutique Hotel & Spa
Superior Apartment, 1 Queen Bed, Balcony, Mountain View | Mountain view
Finca El Tambor

Finca El Tambor

Finca El Tambor
5.0 star property
Antigua Guatemala
9.2 out of 10, Wonderful, (21)
"This was such an amazing experience! From the cleanliness of the room, wonderful staff, delicious foods, breathtaking views, and the overall hospitality, I was hooked! It’s one of the best places to be if you’re looking for a natural environment to observe Mother Nature at her finest. I will definitely be back and would gladly recommend this place over and over again. "
United States
Myema
Finca El Tambor
Couples treatment rooms, body treatments, hot stone massages
El Carmen Hotel

El Carmen Hotel

El Carmen Hotel
3.0 star property
Historic Center
9.0 out of 10, Wonderful, (692)
"Really great shower and excellent rooftop restaurant. "
United States
Kristen
The price is NT$3,706
NT$4,521 total
includes taxes & fees
Dec 17 - Dec 18
El Carmen Hotel
Couples treatment rooms, sauna, steam room, body treatments
Porta Hotel Antigua

Porta Hotel Antigua

Porta Hotel Antigua
4.5 star property
Antigua Guatemala
9.4 out of 10, Exceptional, (1003)
"Everything about this hotel was fantastic. The bed was so comfortable. "
United States
Raymond
The price is NT$5,511
NT$7,036 total
includes taxes & fees
Dec 15 - Dec 16
Porta Hotel Antigua
View from room
Mestizo Antigua

Mestizo Antigua

Mestizo Antigua
4.0 star property
Historic Center
9.4 out of 10, Exceptional, (153)
"The hotel is well situated. The receptionist, Kelyn was amazing, she went out of her way to make my stay comfortable and enjoyable. "
United States
Mercedes
The price is NT$4,490
NT$5,478 total
includes taxes & fees
Jan 8 - 2026/1/9
Mestizo Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Antigua Guatemala Hotel Reviews

Hotel Camino Real Antigua

Hotel Camino Real Antigua

10/10 Excellent
"Amazing hotel with beautiful gardens, great rooms, helpful staff and the top breakfast in Antigua. "
Audrey 2-night trip
Posted 2 days ago
Hotel Camino Real Antigua

Frequently asked questions

Looking for a spa hotel in Antigua Guatemala?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers like the historical sites in Antigua Guatemala. Enjoy the churches and coffeehouses during your vacation. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Antigua Guatemala?
Hotel Museo Spa Casa Santo Domingo is a top luxury spa hotel featuring a fitness center, a hair salon, and an outdoor pool. Treat yourself to a facial, body scrub, or body wrap at the onsite spa. Other popular spa hotels in Antigua Guatemala include Hotel Soleil La Antigua and Hotel Camino Real Antigua.
How many spa hotels will I find in Antigua Guatemala?
Expedia has 27 spa hotels to choose from in Antigua Guatemala.
What's there to see and do in Antigua Guatemala?
Take in the sights and attractions that Antigua Guatemala offers with a visit to Central Park, Antigua Guatemala Colonial Art Museum, and Santa Catalina Arch. If you have spare time during your trip, you might want to make a stop at Santa Clara Convent and Las Capuchinas Convent.
What is a Antigua Guatemala spa hotel?
Spa hotels in Antigua Guatemala provide lodging and have a full on-site spa which offers services including facials and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.