Panama City Vacations
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Bella Vista
1 out of top 10 points of interest in this area
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
1 out of top 10 points of interest in this area
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
Find the Best Panama City Vacation Packages
Panama City Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
NT$3,891
NT$4,280 total
Sep 28 - Sep 29
includes taxes & fees
9/10 Wonderful! (5,902 reviews)
"El desayuno fantásticos"
Reviewed on 2026/9/2
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
NT$5,805
NT$6,386 total
Oct 1 - Oct 2
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
"Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco. The cocktails at the bar delicious and the breakfast was ..."
Reviewed on 2026/9/2
Megapolis Hotel Panamá
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
NT$5,729
NT$6,302 total
Sep 3 - Sep 4
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Panama City attractions
Photo by Fabiola Tile
Multiplaza Pacific Mall
9.0/10 (4,497 reviews)
Panama's premier shopping destination houses over 500 stores, from luxury brands like Gucci to popular retailers like Apple. Obtain the Panama Shopping Card at reception for exclusive discounts throughout the mall.
Amador Causeway
9.0/10 (1,902 reviews)
This man-made causeway connects Panama City to four islands using excavated material from the Panama Canal. Rent a bicycle to explore its entire length, stopping for waterfront dining with skyline views.
Avenida Balboa
8.8/10 (3,608 reviews)
Panama City's iconic waterfront boulevard offers spectacular views of the Pacific Ocean and skyline. Stroll along the Cinta Costera at sunset for a perfect blend of urban energy and coastal tranquility.
Photo by Rob Gosse
Cinta Costera
9.2/10 (3,823 reviews)
This scenic 7 km waterfront promenade showcases Panama City's dramatic skyline against the Pacific Ocean. Stroll through gardens, cycle along dedicated paths, or sample fresh seafood at the nearby Mercado de Mariscos.
Panama Viejo
9.2/10 (3,752 reviews)
Panama Viejo stands as the oldest European settlement on the Pacific coast of the Americas, founded in 1519. Wander among colonial ruins and climb the cathedral tower for a unique perspective on Panama's layered history.
Albrook Shopping Mall
8.6/10 (4,561 reviews)
One of Central America's largest shopping destinations, Albrook Mall features animal-themed corridors with matching statues. Explore 600+ stores, dine at diverse restaurants, or enjoy cinema and bowling.
Fuerte Amador Resort & Marina
9.4/10 (169 reviews)
This bustling marina at the Panama Canal's entrance offers premier yacht services and spectacular city skyline views. Enjoy waterfront dining or book a sunset cruise to experience the canal from a privileged perspective.
Via Espana
8.4/10 (2,902 reviews)
Vía España pulses as Panama City's commercial backbone, lined with shops and diverse dining options. Explore this vibrant thoroughfare during late morning when the urban energy is at its peak.
Frequently asked questions
How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
You're likely to find lower rates and better availability in September, October and November. Take a look at our cheap Panama City vacation packages and you could get some great off-season discounts.
How many days is enough for Panama City?
Dedicate around 3 days for your Panama City vacation in order to discover everything that makes this destination special. Stroll around popular areas, including San Francisco and Campo Alegre. Then check out major sights such as Metropolitan Cathedral of Panama and National Theater. With a good itinerary, you can keep busy with room for some rest time too. Want to travel beyond Panama City? Consider squeezing in an excursion or two.
Is it worth booking a vacation package to Panama City?
Popular for its nature, nightlife and culture, a Panama City vacation is a hit with all types of travelers. Be sure to visit leading sights like Albrook Shopping Mall and Cinta Costera, and consider renting a car for day trips to explore even more.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?
- Choose when to go: Check your schedule and get your bags packed. Your preferred time of year and the available activities will also help you decide when to visit Panama City.
- Plan your budget wisely: As well as the cost of your stay, you'll need to factor in other expenses too. These include food, flights and transportation. Also, put aside a little extra for unexpected costs that could arise during your trip to Panama City.
- Work out your trip length: Think about how long you want to spend exploring Panama City. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
- Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Panama City vacation package.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
