Upstate South Carolina Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Feb 6 - Feb 8
In two months
Mar 20 - Mar 22
In three months
Apr 17 - Apr 19
In four months
May 15 - May 17

Our top choices for Upstate South Carolina vacation rentals

Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is NT$2,810
NT$7,501 total
includes taxes & fees
Jan 26 - Jan 27
Clemson Memorabilia House
View from property

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (56 reviews)
"Excellent stay."
United States
Beonca
The price is NT$2,810
NT$4,481 total
includes taxes & fees
Jan 26 - Jan 27
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
The price is NT$3,035
NT$6,282 total
includes taxes & fees
Jan 26 - Jan 27
Carolina Camp Cedar
Meeting facility

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (789 reviews)
"Spotless wonderful stay"
United States
Tanganica
Mint House Greenville Downtown by Kasa
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (16 reviews)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is NT$6,830
NT$10,118 total
includes taxes & fees
Feb 1 - Feb 2
The Station by Compo Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Great little breakfast! "
Holt 4-night trip
Posted 2 days ago
Embassy Suites Greenville Golf Resort & Conference Center

Find out more about Upstate South Carolina

Search for holiday rentals in Upstate South Carolina on Expedia! You can easily find your home rentals, villas, holiday apartments in Upstate South Carolina using one of the methods below:

  • View our selection of featured holiday rentals in Upstate South Carolina
  • Use the map to find apartments and other holiday homes in the Upstate South Carolina neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Upstate South Carolina while they last

Look no further and take a look at our great range of rental properties in Upstate South Carolina!