Red Roof Inn Upstate South Carolina hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Compare rooms and suites by Red Roof Inn in Upstate South Carolina with rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Upstate South Carolina Red Roof Inn

Red Roof Inn Spartanburg - I-85
Red Roof Inn Spartanburg - I-85
6.8 out of 10, (221)
The price is NT$1,990
NT$2,209 total
includes taxes & fees
Sep 7 - Sep 8

Red Roof Inn Gaffney
Red Roof Inn Gaffney
7.0 out of 10, Good, (422)
The price is NT$1,721
NT$1,927 total
includes taxes & fees
Sep 14 - Sep 15

Red Roof Inn & Suites Duncan
Red Roof Inn & Suites Duncan
6.8 out of 10, (337)
The price is NT$1,907
NT$2,145 total
includes taxes & fees
Sep 17 - Sep 18

Red Roof Inn Spartanburg – I-26
Red Roof Inn Spartanburg – I-26
7.0 out of 10, Good, (721)
The price is NT$1,824
NT$2,024 total
includes taxes & fees
Sep 21 - Sep 22

Red Roof Inn Greenville
Red Roof Inn Greenville
5.8 out of 10, (985)
The price is NT$1,782
NT$1,961 total
includes taxes & fees
Sep 11 - Sep 12
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Upstate South Carolina Hotel Reviews

Hyatt Place Greenville Downtown
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Upstate South Carolina Hotels by Brand
Hotels in Upstate South Carolina Neighborhoods
- Greenville Downtown Hotels
- West End Hotels
- Green Avenue Hotels
- Payne-Logan Hotels
- Turtlehead Hotels
- Hampton-Pinckney Historic District Hotels
- Woodside Cotton Mill Village Historic District Hotels
- Pettigru Street Historic District Hotels
- Pine Ridge Point Hotels
- Colonel Elias Earle Historic District Hotels
Hotels near popular Upstate South Carolina Attractions
- Hotels near Clemson University
- Hotels near Lake Keowee
- Hotels near BMW Performance Center
- Hotels near Falls Park on the Reedy
- Hotels near Bon Secours Wellness Arena
- Hotels near Greenville Convention Center
- Hotels near Haywood Mall
- Hotels near Lake Jocassee
- Hotels near The Peace Center
- Hotels near Lake Hartwell
More Hotel Options in Upstate South Carolina
- Adults Only Resorts & Hotels in Upstate South Carolina
- Adventure Hotels in Upstate South Carolina
- Beach Hotels in Upstate South Carolina
- Boutique Hotels in Upstate South Carolina
- Business Hotels in Upstate South Carolina
- Cheap Hotels in Upstate South Carolina
- Family Hotels in Upstate South Carolina
- Golf Hotels in Upstate South Carolina
- Historic Hotels in Upstate South Carolina
- Hotel Wedding Venues in Upstate South Carolina
- Hotel with a Concierge in Upstate South Carolina
- Hotels with Bars in Upstate South Carolina
- Hotels with Early Check-in in Upstate South Carolina
- Hotels with Free Parking in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels with WiFi in Upstate South Carolina
- Hotels with a Pool in Upstate South Carolina
- Hotels with an Indoor Pool in Upstate South Carolina
- Hotels with smoking rooms in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Pet-friendly Hotels in Upstate South Carolina
- Resorts & Hotels with Spas in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina
- Shopping Hotels in Upstate South Carolina
- Ski Hotels in Upstate South Carolina
More Accommodation Types in Upstate South Carolina
Explore more hotels
- Best Western Plus Clemson Hotel & Conference Center
- Embassy Suites by Hilton Greenville Downtown Riverplace
- Spartanburg Marriott
- The Shepherd Hotel Downtown Clemson
- Holiday Inn Greenville - Woodruff Road by IHG
- Midtown Suites-Greenville
- Aloft Greenville Downtown
- Comfort Inn & Suites Clemson - University Area
- Baymont by Wyndham Greenville Woodruff Rd
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
- Inn @ Clemson
- Days Inn by Wyndham Spartanburg Waccamaw
- Quality Inn Seneca Clemson Area US-123
- Holiday Inn Express Gaffney by IHG
- ECHO Suites Extended Stay by Wyndham Spartanburg
- Holiday Inn Express & Suites Greenville Airport by IHG
- Lakeside Lodge Clemson
- Quality Inn Clinton - Laurens I-26
- Comfort Suites At WestGate Mall