Top 10 Hotels in Southeast Missouri, MO from NT$2,001 - Competitive Prices

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Go beyond your typical stay in Southeast Missouri

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Our top choices for Southeast Missouri hotels

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.

A building with a red awning labeled "Shepherd Mountain Inn."

A compact kitchen with wooden cabinets, a stainless steel refrigerator, and a microwave.

A bathroom with a white sink, a large mirror, a hairdryer, a coffee maker, and a microwave.

1. Shepherd Mountain Inn

Ironton

Michael

NT$3,966

NT$4,333 total

includes taxes & fees

Oct 16 - Oct 17

A motel with a covered entrance, a flag, and a phone number.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A spacious kitchen with a dining area, featuring a ceiling fan, a TV mounted on the wall, and a large rug in the center.

A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

2. Madison Inn Lodge

Fredericktown

Bawan

NT$2,847

NT$3,109 total

includes taxes & fees

Nov 14 - Nov 15

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

3. Hampton Inn & Suites By Hilton Festus

Festus

Abram

NT$2,875

NT$3,288 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A gym with treadmills, elliptical machines, and weight equipment.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

4. Holiday Inn Express & Suites Perryville by IHG

Perryville

Lisa

NT$3,056

NT$3,498 total

includes taxes & fees

Nov 15 - Nov 16

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A corner market with a refrigerated display case and a pantry area.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

5. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Nancy

NT$3,117

NT$3,522 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a plaid sofa, two single beds with patterned bedding, a desk, and a chair.

An outdoor pool area with lounge chairs and an umbrella.

A hotel room with two beds, a desk, a chair, a TV, and a lamp.

A two-story building with a green roof and a large circular sign that reads "Port David Restaurant".

6. Fort Davidson Hotel

Ironton

richard

NT$4,020

NT$4,391 total

includes taxes & fees

Oct 26 - Oct 27

A modern kitchen with a coffee machine, a refrigerator, and a microwave.

A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.

A laundry room with a front-loading washer and dryer, a door, and a light fixture.

A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.

7. Super 8 by Wyndham Farmington

Farmington

Marisa

NT$1,914

NT$2,188 total

includes taxes & fees

Oct 26 - Oct 27

An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

A spacious hotel lobby with a dining area, kitchen, and large windows.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

8. Crown Pointe Lodge, BW Signature Collection

Farmington

CURTIS

NT$3,254

NT$3,721 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with a clear view of the outside through large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

9. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Dean

NT$3,024

NT$3,416 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

10. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

NT$3,249

NT$3,695 total

includes taxes & fees

Oct 25 - Oct 26

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

A gym with cardio equipment, a bench press, and a squat rack.

A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.

11. Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

stewart

NT$1,750

NT$2,001 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a nightstand, and a wall-mounted light fixture.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and framed pictures on the wall.

12. Hampton Inn Poplar Bluff

Poplar Bluff

Rhonda

NT$2,926

NT$3,276 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

13. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Darnetta

NT$3,216

NT$3,628 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a bed, a sofa, a desk, and a chair.

A hotel lobby with a central reception desk, multiple seating areas, and a tiled floor.

A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

14. Holiday Inn Express & Suites Farmington by IHG

Farmington

Sheila

NT$3,699

NT$4,230 total

includes taxes & fees

Nov 15 - Nov 16

A row of single-story houses with attached garages, a paved driveway, and a clear sky.

A modern living room with a flat-screen TV, a desk with a computer, two armchairs, a coffee table, and large windows with a view.

A hotel dining area with tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

A reception desk with a digital map of the USA, a wooden reception area, and a sign for 'MICROHOTEL BY JYNDHAMI'.

15. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

NT$2,722

NT$3,200 total

includes taxes & fees

Nov 15 - Nov 16

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

16. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

NT$2,570

NT$2,781 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

17. Super 8 by Wyndham Perryville

Perryville

Matthew

NT$2,187

NT$2,504 total

includes taxes & fees

Nov 8 - Nov 9

A living room with a blue wall, a fireplace, a sofa, and a chair.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A bar area with stools and a counter where a bartender is serving drinks.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

18. EC Reed's Mercantile and Hotel

Marble Hill

Miranda

NT$3,382

NT$3,682 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

19. Drury Inn & Suites Jackson MO

Jackson

Debra S

NT$2,605

NT$2,754 total

includes taxes & fees

Nov 1 - Nov 2

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

20. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

NT$3,253

NT$3,670 total

includes taxes & fees

Oct 25 - Oct 26

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Vacation Rentals in Southeast Missouri

Cabin

A view through a window with a stone wall and a wooden structure in the background.

A room with two bunk beds, a single bed, a ceiling fan, and a window with blinds.

Sam A Baker State Park

Patterson

"Pet friendly, great staff. "

Cottage

A dining area with a checkered tablecloth, wooden chairs, and a red rug.

A swimming pool with a wooden deck, surrounded by a white picket fence, and featuring colorful umbrellas.

An outdoor patio with a table and chairs, a grill, and a large umbrella.

A modern kitchen with wooden cabinets, a microwave, and a refrigerator. There is a staircase leading to another level. A gray sofa with a red pillow is in the living area, and a checkered curtain covers a window.

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

Ironton

"Stroller, pack n play and high chair. This was amazing "

Aparthotel

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a sign that reads "The Atrium Boutique Hotel".

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

The Atrium - A Boutique Hotel

Perryville

"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."

Cabin

A bedroom with a bed, a wooden headboard, a window with a view of greenery, and a tray with breakfast items.

A rustic cabin with a wooden exterior, a small deck, and a picnic table.

A cabin with two Adirondack chairs outside, a picnic table, and a small black structure with a window and a sign.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

"The stay here gets better every time."

Aparthotel

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

A hallway with exposed brick walls, wooden flooring, and a white door.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

Urban Lofts

Perryville

"Beautiful place and staff was amazing!"

Vacation Home

A wooden deck with two Adirondack chairs and a hammock.

A spacious living room with wooden floors, a stone fireplace, and a mounted television.

A spacious living room with a wooden ceiling, a ceiling fan, a sofa set, a coffee table, and a large window offering a view of the outdoors.

A bedroom with a large bed, wooden ceiling, and a view of the outdoors.

Tiny Houses of French Village

French Village

"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "

Cabin

A bedroom with a wooden bed, a bench, and a window.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

Lake Wappapello

Williamsville

"Pet friendly. Family-friendly "

Cottage

A bedroom with a large bed, a sofa, a wooden wardrobe, and a ceiling fan.

A single-story house with a front porch, a stone foundation, and a well-maintained lawn.

A covered porch with yellow chairs, a bench, and a small table.

A spacious living area with a kitchen island, dining table, and a television.

Walk to Dtwn: Ironton Home in Historic District

Ironton

"Clean and comfortable "

Cottage

A cozy cabin interior with a wooden interior, a fireplace, a television, and a comfortable seating area.

Walk to Current River: Ozarks Adventure Home!

Van Buren

"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."

Cottage

A spacious living room with a high wooden ceiling, two sofas, a coffee table, a TV, and a bookshelf.

A red house with a wooden deck, large sliding glass doors, and a chimney.

A red house with a wooden deck and stone steps leading to a porch.

A dining area with a glass table and chairs, wooden flooring, and large windows.

Cozy Belgrade Cottage w/ Wood-burning Stove!

Belgrade

Cottage

A bedroom with a bed, nightstand, lamp, and curtains.

A living room with a sofa, coffee table, TV stand, and ceiling fan.

A kitchen with granite countertops, white cabinets, a coffee maker, a kettle, and a sink.

A single-story house with a front porch, a small front yard, and a red roof.

Cottage w/ Yard, Walk to Historic Attractions

Ste Genevieve

"The little blue cottage was very comfortable, clean and close to everything downtown. We parked the car and walked everywhere. It was on a quiet street. The bed was comfy, clean kitchen. We liked the little back yard, for relaxing. "

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Stay near popular Southeast Missouri attractions

A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.

Elephant Rocks State Park

9.6/10 (98 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

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A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

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A sunset over a lake with boats and ducks.

Lake Wappapello

8.8/10 (54 reviews)

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)

Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

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Century Casino Caruthersville

7.0/10 (57 reviews)

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.

Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent

"Our room was spacious, clean and the bed was super comfortable!"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Very friendly & professional staff. Trustworthy room attendants, with attention to details. Beds comfortable. Everyone enjoyed the morning breakfast, with a good menu. Cocktail hour widely attended. Would definitely stay here again!"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"The room was clean, the pillows were great and the bed was comfy. the dinner service and breakfast were very nice and the staff was helpful and friendly! 10/10"

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"We have visited the area many times in the past few years and have had terrible luck at hotels all around the area. This was such a breath of fresh air. The property was beautiful, the room was super clean, the staff was so pleasant and helpful. Breakfast was tasty and the bed was super comfortable. We have found out hotel when we come to town."

Hampton Inn Poplar Bluff

10/10 Excellent

"The staff at checking was pleasant but one older man kept downgrading the governor of my state. Although I agreed with much of east he said I thought it was inappropriate to push without knowing where I stood. The actual young man who checked me in was very nice and was not part of the political conversation. With that said I would still stay at this hotel in the future as it was otherwise a very pleasant stay. Good breakfast in the morning. The room was very quiet."

Hampton Inn Sikeston

10/10 Excellent

"Everyone was so nice. The rooms were clean and the breakfast had a good variety ."

Motel 6 Poplar Bluff, MO

8/10 Good

"They let pets stay free!!! No deposit no size limits."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

NT$1,750

NT$2,001 total

Nov 1 - Nov 2

includes taxes & fees

8/10 Very Good! (1,003 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

NT$2,133

NT$2,431 total

Oct 19 - Oct 20

includes taxes & fees

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

NT$2,229

NT$2,496 total

Oct 29 - Oct 30

includes taxes & fees

8/10 Very Good! (1,001 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

NT$2,315

NT$2,612 total

Oct 26 - Oct 27

includes taxes & fees

9.2/10 Wonderful! (1,004 reviews)

Comfort Inn Festus - St Louis South

1303 Veterans Blvd Festus MO

NT$2,290

NT$2,676 total

Nov 4 - Nov 5

includes taxes & fees

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

NT$2,926

NT$3,276 total

Nov 1 - Nov 2

includes taxes & fees

9.4/10 Exceptional! (985 reviews)

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, featuring scenic parks and recreational activities that invite exploration.
Cultural Experiences: Engage with local culture through campus tours, breweries, and historic civic buildings that reflect the region’s heritage.
Charming Neighborhoods: Stroll through friendly neighborhoods that offer a welcoming atmosphere and a taste of local life.
Family-Friendly Activities: The area provides a variety of activities suitable for families, making it an ideal vacation spot.
Warm Hospitality: Enjoy the warmth of Southern hospitality in a range of charming hotels and lodges.

Find great hotels near Southeast Missouri

Discover a range of charming hotels in Southeast Missouri, perfect for business travelers, adventure seekers, and couples looking for a romantic getaway. Whether you’re searching for the closest accommodations or the best-reviewed options, you’ll find a variety of lodges and hotels that cater to your needs. Embrace the warmth of Southern hospitality and make your stay in Southeast Missouri a memorable one.

Madison Inn Lodge: A welcoming motel ideal for business travelers and pet owners alike, Madison Inn Lodge is located 25.7km from Southeast Missouri. This property offers a practical and comfortable stay with amenities tailored for those traveling with pets. Guests appreciate the pet-friendly policy, which includes restrictions to ensure a pleasant environment for all. The lodge features essential amenities designed for business needs, making it a great choice for corporate travelers seeking convenience and comfort.
Shepherd Mountain Inn: Positioned 33.8km from Southeast Missouri, Shepherd Mountain Inn stands as a solid choice for business travelers. This hotel combines a professional atmosphere with essential amenities, ensuring a smooth and productive stay. Guests often note the hotel's commitment to providing a comfortable environment, making it suitable for those on work trips or visiting the area for business events. Its strategic location also allows easy access to local attractions, enhancing the overall experience.
Alpaca Farm Stay: Located 12.9km from Southeast Missouri, Alpaca Farm Stay offers a unique and adventurous escape for families and couples. This lodge invites guests to immerse themselves in a delightful rural setting, featuring adventure sports options like kayaking, mountain climbing, and fishing nearby. Families will enjoy the shared playground for children, while couples can take advantage of romantic packages. With stunning lake and mountain views available, this property ensures a memorable getaway filled with excitement and relaxation.

Where to stay near Southeast Missouri

In Southeast Missouri, visitors can enjoy a blend of outdoor adventures and picturesque scenery perfect for families. Enjoy leisurely strolls through charming neighborhoods, where friendly locals create a welcoming atmosphere. This region is known for its scenic retreats and recreational activities, making it an ideal vacation spot. With convenient locations and vibrant community vibes, Southeast Missouri promises a delightful experience for all travelers looking to unwind and explore.

Central Fredericktown: Nestled about 16.1km from Southeast Missouri, Central Fredericktown is a charming village that attracts visitors year-round, with peak seasons occurring from June to August. This quaint area is ideal for families seeking outdoor adventures and city-themed experiences. Notable activities include exploring the local recreational areas, shopping at the mall center, and visiting the history museum. The village is home to lovely parks and urban greenspaces, providing ample opportunities for relaxation and enjoyment. Central Fredericktown offers a delightful mix of history and recreation that makes it a perfect stop for tourists.
Annapolis: Located approximately 22.5km away from Southeast Missouri, Annapolis is a vibrant city known for its stunning scenery and adventurous spirit. The city sees a steady stream of visitors throughout the year, peaking in June, July, and September. Travelers flock to Annapolis for its outdoor activities and picturesque landscapes, including national state parks and rivers. With recreational areas and an arena entertainment facility, there’s no shortage of fun and excitement. Whether you’re hiking through scenic trails or enjoying a day by the water, Annapolis promises an unforgettable experience for all types of adventurers.
Des Arc: Situated around 17.7km from Southeast Missouri, Des Arc is a lively city that experiences seasonal fluctuations in visitor numbers, with the summer months from June to August being the most popular. Known for its outdoor activities and natural beauty, Des Arc is a haven for adventure seekers. Visitors can enjoy recreational areas, a water park, and an arena entertainment facility. The nearby national state park, lake, and river provide the perfect backdrop for a day of exploration and relaxation. Des Arc is an excellent destination for those looking to immerse themselves in nature while enjoying a variety of fun-filled activities.

Things to do near Southeast Missouri

Southeast Missouri offers a wealth of outdoor adventures and scenic beauty, perfect for a memorable vacation. Engage in campus tours, outdoor activities, and sports tournaments, or explore local breweries on guided tours. Educational experiences abound, making it an excellent destination for those seeking both fun and learning. With recreational areas and entertainment facilities, there's something for everyone to enjoy in this vibrant region.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a variety of local goods. For a more traditional mall experience, check out the Farmington Mineral Area Shopping Center, 48.3km away, featuring entertainment and family-friendly shops.

Recreation

Crane Lake Recreation Area offers a serene environment perfect for relaxation and wellness activities, surrounded by nature's beauty. Silver Mine Recreation Area provides a tranquil setting for rejuvenation, while Arcadia Valley Golf Club combines outdoor sports with stunning landscapes, making it ideal for both leisure and recreation.

Adventure

At Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri, enjoy exhilarating mountain biking and scenic hiking. The trails offer a thrilling adventure amidst picturesque landscapes, perfect for outdoor enthusiasts seeking both excitement and natural beauty.

Nightlife

In Southeast Missouri, Cape Girardeau's Riverfront offers vibrant bars and live music, while Sikeston's popular casinos provide exciting gaming and entertainment options. Enjoy the lively atmosphere, delicious local cuisine, and friendly crowds at these nightlife hotspots, perfect for an unforgettable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money on your trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to find hotel deals by filtering options to suit your budget and preferences, including eco-certified hotels. Additionally, booking a package that combines flights and hotel stays can yield significant savings. Make sure to compare room rates to secure the best deal available for your accommodation.

The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. If you're looking for the best prices and deals, simply arrange the price filter from lowest to highest.
Consider bundling your trip: You can save money by booking an Expedia package that combines your hotel accommodations in Southeast Missouri with your flights and activities.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a fantastic getaway for outdoor enthusiasts and culture seekers alike. Visitors can explore scenic urban parks, national state parks, and historic civic government buildings. The area is perfect for those looking to connect with nature and experience local culture. Additionally, travelers can check out nearby attractions and visit Southeast Missouri State University for a taste of local education and community life.

Walnut Hollow Lake: Experience the serene beauty of Walnut Hollow Lake, located 20.9km from Southeast Missouri. This picturesque lake offers a charming beach, perfect for romantic getaways or family outings amidst stunning scenery.
K Bridge Recreation Area: Just 27.4km away, K Bridge Recreation Area is an urban park that caters to families and city dwellers alike. Enjoy outdoor activities surrounded by lush landscapes, making it an ideal spot for a fun-filled day with loved ones.
Millstream Gardens Conservation Area: Situated 24.1km from the city, this reserve offers a blend of adventure and relaxation. With its welcoming atmosphere, Millstream Gardens is perfect for families, and you can explore its historical significance while enjoying nature.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	34.9°F (1.6°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low
February	38.1°F (3.4000000000000004°C)	Light Rain	Mostly Sunny	Slightly Low	Average
March	48.0°F (8.9°C)	Light Rain	Mostly Sunny	Average	Average
April	57.6°F (14.2°C)	Light Rain	Mostly Sunny	Average	Slightly High
May	67.3°F (19.6°C)	Light Rain	Mostly Sunny	Average	Average
June	76.5°F (24.700000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
July	79.2°F (26.200000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Average
August	77.2°F (25.1°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
September	71.6°F (22.0°C)	Light Rain	Mostly Sunny	Average	Average
October	59.9°F (15.5°C)	Light Rain	Mostly Sunny	Average	Average
November	47.5°F (8.6°C)	Light Rain	Mostly Sunny	Average	Slightly Low
December	39.4°F (4.1000000000000005°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low

The nearest major airports for your trip to Southeast Missouri

Traveling to Southeast Missouri can be conveniently done by flying into one of its major airports. St. Louis Lambert International Airport (STL) is located 154.5km away, with nearby hotel options like The Ritz-Carlton and Ameristar Casino Resort, both about 11.3km from the airport. Fort Leonard Wood Regional Airport (TBN) is also 154.5km away, featuring hotels such as Z Loft Extended Stay Hotel, 9.7km from the terminal. Alternatively, Marion Williamson County Regional Airport (MWA) is 133.6km away, offering accommodations like Drury Inn & Suites just 3.2km from the airport. Each airport provides various transportation services for easy access to local hotels.

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Our top choices for Southeast Missouri hotels

1. Shepherd Mountain Inn

2. Madison Inn Lodge

3. Hampton Inn & Suites By Hilton Festus

4. Holiday Inn Express & Suites Perryville by IHG

5. Fairfield Inn & Suites by Marriott Poplar Bluff

6. Fort Davidson Hotel

7. Super 8 by Wyndham Farmington

8. Crown Pointe Lodge, BW Signature Collection

9. Drury Inn & Suites Poplar Bluff

10. Fairfield Inn & Suites by Marriott Sikeston

11. Baymont Inn and Suites by Wyndham Farmington, MO

12. Hampton Inn Poplar Bluff

13. Drury Plaza Hotel Cape Girardeau Conference Center

14. Holiday Inn Express & Suites Farmington by IHG

15. Microtel Inn & Suites by Wyndham Sainte Genevieve

16. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

17. Super 8 by Wyndham Perryville

18. EC Reed's Mercantile and Hotel

19. Drury Inn & Suites Jackson MO

20. Fairfield Inn & Suites by Marriott Cape Girardeau

Vacation Rentals in Southeast Missouri

Sam A Baker State Park

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

The Atrium - A Boutique Hotel

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Urban Lofts

Tiny Houses of French Village

Lake Wappapello

Walk to Dtwn: Ironton Home in Historic District

Walk to Current River: Ozarks Adventure Home!

Cozy Belgrade Cottage w/ Wood-burning Stove!

Cottage w/ Yard, Walk to Historic Attractions

Stay near popular Southeast Missouri attractions

Elephant Rocks State Park

Southeast Missouri State University

Lake Wappapello

Century Casino & Hotel Cape Girardeau

Century Casino Caruthersville

Learn more about Southeast Missouri

Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Hayti Caruthersville

Hampton Inn Poplar Bluff

Hampton Inn Sikeston

Motel 6 Poplar Bluff, MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Days Inn and Suites by Wyndham Sikeston

Motel 6 Poplar Bluff, MO

Pear Tree Inn Cape Girardeau West

Comfort Inn Festus - St Louis South

Hampton Inn Poplar Bluff

Hotels in Southeast Missouri with star-rating

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