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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Room was spotless, staff was SO kind. 5 day trip, stayed in 4 different hotels & this one was BY FAR the nicest. Breakfast was fabulous. 10 out of 10 recommend!! "
United States
Brenda
The price is NT$2,621
NT$2,771 total
includes taxes & fees
Jan 21 - Jan 22
Drury Inn & Suites Jackson MO

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (472 reviews)
"Clean room, very nice staff"
United States
Mack
The price is NT$2,400
NT$2,729 total
includes taxes & fees
Jan 30 - Jan 31
The Farmstead Hotel

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
"Great place "
United States
Kelly
The price is NT$2,842
NT$3,206 total
includes taxes & fees
Jan 21 - Jan 22
Drury Plaza Hotel Cape Girardeau Conference Center

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1,000 reviews)
"Clean room/friendly staff "
United States
Sloan
The price is NT$1,800
NT$1,899 total
includes taxes & fees
Jan 18 - Jan 19
Motel 6 Poplar Bluff, MO

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (978 reviews)
"Great location and room "
United States
Curtis
The price is NT$3,284
NT$3,710 total
includes taxes & fees
Feb 6 - Feb 7
Drury Inn & Suites Poplar Bluff

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (219 reviews)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is NT$5,179
NT$5,476 total
includes taxes & fees
Jan 18 - Jan 19
Echo Bluff State Park

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (864 reviews)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
United States
Brenda
The price is NT$3,275
NT$3,700 total
includes taxes & fees
Jan 31 - Feb 1
Fairfield Inn & Suites by Marriott Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (798 reviews)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is NT$3,420
NT$3,830 total
includes taxes & fees
Feb 14 - Feb 15
Hampton Inn Poplar Bluff

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,011 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is NT$2,257
NT$2,572 total
includes taxes & fees
Jan 20 - Jan 21
Best Western Plus Sikeston

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (551 reviews)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
The price is NT$2,874
NT$3,290 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Perryville by IHG

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,002 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
United States
Nicole
The price is NT$2,968
NT$3,413 total
includes taxes & fees
Jan 25 - Jan 26
Drury Inn & Suites Sikeston, MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (730 reviews)
"Clean room and easy access to room"
United States
Anne
The price is NT$1,752
NT$1,997 total
includes taxes & fees
Jan 19 - Jan 20
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (714 reviews)
"Amazing place"
United States
Mladen
The price is NT$3,474
NT$3,925 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Poplar Bluff by IHG

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (336 reviews)
"Staff was very friendly."
United States
Joyce
The price is NT$2,842
NT$3,081 total
includes taxes & fees
Jan 18 - Jan 19
Honeysuckle Inn - Mountain View

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (687 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is NT$2,550
NT$2,760 total
includes taxes & fees
Jan 22 - Jan 23
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (150 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
The price is NT$2,782
NT$3,138 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Cape Girardeau

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (463 reviews)
"Very clean and super friendly staff!"
United States
Katherine
The price is NT$3,214
NT$3,639 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Staff great. "
United States
Nancy
The price is NT$3,351
NT$3,780 total
includes taxes & fees
Jan 18 - Jan 19
Pear Tree Inn Cape Girardeau Near the Medical Center

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very Good, (905 reviews)
"Breakfast was great! Location right off interstate was perfect. The property is a little old."
United States
Mindy
The price is NT$2,899
NT$3,315 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (706 reviews)
"Clean room and great staff"
United States
Stacy
The price is NT$3,853
NT$4,406 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Jan 23 - Jan 25

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Stay near popular Central United States attractions

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

  • Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, featuring scenic parks and recreational activities that invite exploration.
  • Cultural Experiences: Engage with local culture through campus tours, breweries, and historic civic buildings that reflect the region’s heritage.
  • Charming Neighborhoods: Stroll through friendly neighborhoods that offer a welcoming atmosphere and a taste of local life.
  • Family-Friendly Activities: The area provides a variety of activities suitable for families, making it an ideal vacation spot.
  • Warm Hospitality: Enjoy the warmth of Southern hospitality in a range of charming hotels and lodges.

Find great hotels near Southeast Missouri

Discover a range of charming hotels in Southeast Missouri, perfect for business travelers, adventure seekers, and couples looking for a romantic getaway. Whether you’re searching for the closest accommodations or the best-reviewed options, you’ll find a variety of lodges and hotels that cater to your needs. Embrace the warmth of Southern hospitality and make your stay in Southeast Missouri a memorable one.

  • Madison Inn Lodge: A welcoming motel ideal for business travelers and pet owners alike, Madison Inn Lodge is located 25.7km from Southeast Missouri. This property offers a practical and comfortable stay with amenities tailored for those traveling with pets. Guests appreciate the pet-friendly policy, which includes restrictions to ensure a pleasant environment for all. The lodge features essential amenities designed for business needs, making it a great choice for corporate travelers seeking convenience and comfort.
  • Shepherd Mountain Inn: Positioned 33.8km from Southeast Missouri, Shepherd Mountain Inn stands as a solid choice for business travelers. This hotel combines a professional atmosphere with essential amenities, ensuring a smooth and productive stay. Guests often note the hotel's commitment to providing a comfortable environment, making it suitable for those on work trips or visiting the area for business events. Its strategic location also allows easy access to local attractions, enhancing the overall experience.
  • Alpaca Farm Stay: Located 12.9km from Southeast Missouri, Alpaca Farm Stay offers a unique and adventurous escape for families and couples. This lodge invites guests to immerse themselves in a delightful rural setting, featuring adventure sports options like kayaking, mountain climbing, and fishing nearby. Families will enjoy the shared playground for children, while couples can take advantage of romantic packages. With stunning lake and mountain views available, this property ensures a memorable getaway filled with excitement and relaxation.

Where to stay near Southeast Missouri

In Southeast Missouri, visitors can enjoy a blend of outdoor adventures and picturesque scenery perfect for families. Enjoy leisurely strolls through charming neighborhoods, where friendly locals create a welcoming atmosphere. This region is known for its scenic retreats and recreational activities, making it an ideal vacation spot. With convenient locations and vibrant community vibes, Southeast Missouri promises a delightful experience for all travelers looking to unwind and explore.

  • Central Fredericktown: Nestled about 16.1km from Southeast Missouri, Central Fredericktown is a charming village that attracts visitors year-round, with peak seasons occurring from June to August. This quaint area is ideal for families seeking outdoor adventures and city-themed experiences. Notable activities include exploring the local recreational areas, shopping at the mall center, and visiting the history museum. The village is home to lovely parks and urban greenspaces, providing ample opportunities for relaxation and enjoyment. Central Fredericktown offers a delightful mix of history and recreation that makes it a perfect stop for tourists.
  • Annapolis: Located approximately 22.5km away from Southeast Missouri, Annapolis is a vibrant city known for its stunning scenery and adventurous spirit. The city sees a steady stream of visitors throughout the year, peaking in June, July, and September. Travelers flock to Annapolis for its outdoor activities and picturesque landscapes, including national state parks and rivers. With recreational areas and an arena entertainment facility, there’s no shortage of fun and excitement. Whether you’re hiking through scenic trails or enjoying a day by the water, Annapolis promises an unforgettable experience for all types of adventurers.
  • Des Arc: Situated around 17.7km from Southeast Missouri, Des Arc is a lively city that experiences seasonal fluctuations in visitor numbers, with the summer months from June to August being the most popular. Known for its outdoor activities and natural beauty, Des Arc is a haven for adventure seekers. Visitors can enjoy recreational areas, a water park, and an arena entertainment facility. The nearby national state park, lake, and river provide the perfect backdrop for a day of exploration and relaxation. Des Arc is an excellent destination for those looking to immerse themselves in nature while enjoying a variety of fun-filled activities.

Things to do near Southeast Missouri

Southeast Missouri offers a wealth of outdoor adventures and scenic beauty, perfect for a memorable vacation. Engage in campus tours, outdoor activities, and sports tournaments, or explore local breweries on guided tours. Educational experiences abound, making it an excellent destination for those seeking both fun and learning. With recreational areas and entertainment facilities, there's something for everyone to enjoy in this vibrant region.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a variety of local goods. For a more traditional mall experience, check out the Farmington Mineral Area Shopping Center, 48.3km away, featuring entertainment and family-friendly shops.

Recreation

Crane Lake Recreation Area offers a serene environment perfect for relaxation and wellness activities, surrounded by nature's beauty. Silver Mine Recreation Area provides a tranquil setting for rejuvenation, while Arcadia Valley Golf Club combines outdoor sports with stunning landscapes, making it ideal for both leisure and recreation.

Adventure

At Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri, enjoy exhilarating mountain biking and scenic hiking. The trails offer a thrilling adventure amidst picturesque landscapes, perfect for outdoor enthusiasts seeking both excitement and natural beauty.

Nightlife

In Southeast Missouri, Cape Girardeau's Riverfront offers vibrant bars and live music, while Sikeston's popular casinos provide exciting gaming and entertainment options. Enjoy the lively atmosphere, delicious local cuisine, and friendly crowds at these nightlife hotspots, perfect for an unforgettable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money on your trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to find hotel deals by filtering options to suit your budget and preferences, including eco-certified hotels. Additionally, booking a package that combines flights and hotel stays can yield significant savings. Make sure to compare room rates to secure the best deal available for your accommodation.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. If you're looking for the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by booking an Expedia package that combines your hotel accommodations in Southeast Missouri with your flights and activities.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a fantastic getaway for outdoor enthusiasts and culture seekers alike. Visitors can explore scenic urban parks, national state parks, and historic civic government buildings. The area is perfect for those looking to connect with nature and experience local culture. Additionally, travelers can check out nearby attractions and visit Southeast Missouri State University for a taste of local education and community life.

  • Walnut Hollow Lake: Experience the serene beauty of Walnut Hollow Lake, located 20.9km from Southeast Missouri. This picturesque lake offers a charming beach, perfect for romantic getaways or family outings amidst stunning scenery.
  • K Bridge Recreation Area: Just 27.4km away, K Bridge Recreation Area is an urban park that caters to families and city dwellers alike. Enjoy outdoor activities surrounded by lush landscapes, making it an ideal spot for a fun-filled day with loved ones.
  • Millstream Gardens Conservation Area: Situated 24.1km from the city, this reserve offers a blend of adventure and relaxation. With its welcoming atmosphere, Millstream Gardens is perfect for families, and you can explore its historical significance while enjoying nature.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowSlightly Low
February38.1°F (3.4000000000000004°C)Light RainMostly SunnySlightly LowAverage
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.700000000000003°C)Light RainMostly SunnySlightly HighSlightly High
July79.2°F (26.200000000000003°C)Light RainMostly SunnySlightly HighAverage
August77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December39.4°F (4.1000000000000005°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Southeast Missouri

Traveling to Southeast Missouri can be conveniently done by flying into one of its major airports. St. Louis Lambert International Airport (STL) is located 154.5km away, with nearby hotel options like The Ritz-Carlton and Ameristar Casino Resort, both about 11.3km from the airport. Fort Leonard Wood Regional Airport (TBN) is also 154.5km away, featuring hotels such as Z Loft Extended Stay Hotel, 9.7km from the terminal. Alternatively, Marion Williamson County Regional Airport (MWA) is 133.6km away, offering accommodations like Drury Inn & Suites just 3.2km from the airport. Each airport provides various transportation services for easy access to local hotels.

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