Drury Inn & Suites Southeast Missouri hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Southeast Missouri Drury Inn & Suites
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place!"
Jennifer
The price is NT$3,536
NT$4,066 total
includes taxes & fees
Jul 8 - Jul 9
9.4 out of 10, Exceptional, (1,003 reviews)
"Great place"
Sonya
The price is NT$3,121
NT$3,557 total
includes taxes & fees
Jul 12 - Jul 13
9.6 out of 10, Exceptional, (1,006 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
William
The price is NT$3,057
NT$3,232 total
includes taxes & fees
Jul 23 - Jul 24
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
Stephanie
The price is NT$2,995
NT$3,383 total
includes taxes & fees
Jul 12 - Jul 13
9.4 out of 10, Exceptional, (1,003 reviews)
"I will definitely be staying here next time I visit SEMO."
Lee
The price is NT$3,503
NT$3,952 total
includes taxes & fees
Jul 5 - Jul 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Sikeston, MO
10/10 Excellent
Explore a world of travel with Expedia
- Hotels near Sand Creek Winery
- Hotels with Bars in Jackson
- Hotels with an Indoor Pool in Bonne Terre
- Hotel Wedding Venues Hotels in Perryville
- Hotels near Walnut Hollow Lake
- Pet-Friendly Hotels in Perryville
- Casino Hotels in Farmington
- Hotel Wedding Venues Hotels in Southeast Missouri
- Pilot Knob Hotels
- Hotels with a Pool in Fredericktown
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Romantic Hotels in Poplar Bluff
- Hotel Wedding Venues Hotels in Farmington
- Van Buren Hotels
- Marble Hill Hotels
- Hotels near Taum Sauk Mountain State Park
- 3 Star Hotels in Doe Run
- Farmington Hotels
- Hotels near Missouri's National Veterans Memorial
- Hotels near Johnson's Shut-ins State Park
- Fredericktown Hotels
- Hotels with smoking rooms in Farmington
- Pet-Friendly Hotels in Poplar Bluff
- Hotels with Bars in Farmington
- Cheap Hotels in Poplar Bluff
- Hotels with a Pool in Bonne Terre
- Bonne Terre Hotels
- Belleview Hotels
- Potosi Hotels
- Luxury Hotels in Farmington
- Hotels with an Indoor Pool in Poplar Bluff
- Cheap Hotels in Farmington
- Hotels near Millstream Gardens Conservation Area
- Hotels near Elephant Rocks State Park
- Black Hotels
- Perryville Hotels
- Hotels near Mo-Ark Regional Railroad Museum
- Motels in Belleview
- Adults Only Resorts & in Southeast Missouri
- Hotels near St. James Catholic Church
- Hotels near Big River
- Hotels with Hot Tubs in Poplar Bluff
- Resorts & Hotels with Spas in Perryville
- Park Hills Hotels
- Cottages in Wayne County
- Hotels with an Indoor Pool in Jackson
- Bloomfield Hotels
- Flights from Friedheim
- Flights from Minneapolis (MSP) to Poplar Bluff (POF)
- Flights to Fredericktown
- Flights from Ada (ADT) to Poplar Bluff (POF)
- Flights from St. Louis (SUS) to Poplar Bluff (POF)
- Flights from Park Hills
- Flights from Jasper (APT) to Poplar Bluff (POF)
- Flights from Los Angeles (LAX) to Poplar Bluff (POF)
- Flights from Black
- Flights from Mountain Home (WMH) to Poplar Bluff (POF)
- Flights from Southeast Missouri
- Flights from Murray (CEY) to Poplar Bluff (POF)
- Flights from Valles Mines
- Flights from Branson (BKG) to Poplar Bluff (POF)
- Flights to Southeast Missouri
- Flights from Belleview
- Flights from Fredericktown
- Flights to Ironton
- Flights from New Offenburg
- Visit Jackson
- Walnut Hollow Lake
- Johnson's Shut-ins State Park
- Visit Middle Brook
- Visit Dutchtown
- Visit Annapolis
- Twin Oaks Vineyard & Winery
- St. James Catholic Church
- Visit Zalma
- Visit Ellington
- Crown Valley Winery
- Visit Ironton
- Taum Sauk Mountain State Park
- Visit Desloge
- Visit Belleview
- Visit Lesterville
- Visit Cadet
- Visit Flat River
- National Shrine of Our Lady of the Miraculous Medal
- Visit Farmington
- Visit Friedheim
- Visit Marble Hill
- Weingarten Vineyard
- National Car Rental Rental Cars in Arcadia
- Car rental Piedmont
- Rental cars Poplar Bluff Municipal airport
- Enterprise Rental Cars in Bonne Terre
- Dollar Rent A Car Rental Cars in Pocahontas
- Routes Rental Cars in Black
- Car rental Wappapello
- Hertz Rental Cars in Park Hills
- Car rental Jackson
- Budget Rental Cars in Poplar Bluff
- Car rental Doe Run