Southeast Minnesota Vacations

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Where to stay in Southeast Minnesota

Find the best Southeast Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southeast Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area
4.5/5(250 area reviews)

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Find hotels in Downtown Rochester

Find the Best Southeast Minnesota Vacation Packages

Southeast Minnesota Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (1,523 reviews)
Great stay but complicated arrival by car
"Both staffing arrival and Mayo Clinic construction will continue to be a challenge for guests at the Kahler Grand for a few months. Hopefully more bell/valet staff can be added and arrival moved back to proper entrance. Until then arrival by car for registration can be chaotic/-once insid at the ..."

Reviewed on 2025/8/17

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Kahler Grand Hotel
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is NT$3,090 per night from Aug 29 to Aug 30
NT$3,090
NT$3,557 total
Aug 29 - Aug 30
includes taxes & fees
9/10 Wonderful! (996 reviews)
"Room smelled exceptionally clean upon opening the door! Nothing in the room was dated or worn. We haven’t seen that lately in other stays!"

Reviewed on 2025/8/17

Hyatt House Rochester/Mayo Clinic Area
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is NT$2,193 per night from Aug 24 to Aug 25
NT$2,193
NT$2,524 total
Aug 24 - Aug 25
includes taxes & fees
9.2/10 Wonderful! (104 reviews)
"The only hot food is waffles bed was extremely comfortable staff was amazing kept up with keeping breakfast stocked and clean at all times will stay agin"

Reviewed on 2025/8/16

Spark by Hilton Rochester South
See all 924 properties in Southeast Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southeast Minnesota

Winona State University

Winona State University

Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.

Winona State University
Guided tours are offered at Mystery Cave where we came upon this little body of water down in the cave. It was very cool!! The water was so clear and beautiful!! #InStone

Forestville Mystery Cave State Park

Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.

Forestville Mystery Cave State Park

Mayo Clinic Hospital - Saint Marys Campus

Though Mayo Clinic Hospital - Saint Marys Campus might be what brings you to town, perhaps you'll have a chance to explore more of Rochester while you are here.

Mayo Clinic Hospital - Saint Marys Campus

Frequently asked questions

How much does a Southeast Minnesota vacation package cost?
Our Southeast Minnesota vacation packages, which start from as low as , are an ideal way to save. Select your favorite flights, hotels and rental cars to create a personalized itinerary.
How do I get a cheap travel package to Southeast Minnesota?
Bundle your flights and hotels with Expedia to save on your next exciting adventure. With more than 550 partner airlines and 1,000,000 properties across the globe, your Southeast Minnesota vacation package can be tailored exactly to suit your travel style. With all those extra dollars, why not add a few interesting activities and tours? It's an easy way to unlock even more discounts. The vacation you've always dreamed of in Southeast Minnesota is much closer than you thought!
What are the top hotels in Southeast Minnesota?
For hotels in Rochester with comfy beds and friendly service, you can't go past Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you plan to visit Lake City as well, you'll get a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southeast Minnesota vacation?
Travelers are usually able to browse international airfares on Expedia within 12 months of the departure date. Booking last minute? With a little bit of luck, it's still possible to score an affordable ticket only weeks before your flight.
What does an Expedia Southeast Minnesota travel package include?
It's up to you! You can select from a range of Southeast Minnesota bundles, such as a flight, hotel and rental car. You can also book a hotel with a flight, or a rental car with a flight. Once you've made your booking, you can add the fun stuff like activities and experiences. Whatever your perfect Southeast Minnesota getaway looks like, you'll save!
What should I know before booking a Southeast Minnesota travel package?
Our prices are always low. However, you'll grab even more savings if you book your flights, hotels and car rentals together. With an Expedia travel package, you'll always get transparent pricing and lots of choice.
Can I choose my airline with a Southeast Minnesota Expedia vacation package?
Yes, you sure can. We have more than 550 partner airlines across the globe, so pick the carrier that fits your travel needs.
If I'm not able to travel, can I cancel my Southeast Minnesota vacation package?
It's impossible to predict what the future holds, so it's comforting to know that you can cancel or change your Southeast Minnesota vacation package. If your booking was made in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for further details.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.