Find Boutique Hotels in South Carolina Midlands, SC
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Top South Carolina Midlands Boutique Hotels
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Recommended hotels in South Carolina Midlands
Tru By Hilton Santee
Santee
9.2 out of 10, Wonderful, (630)
"Nice place to stay"
Tanya
The price is NT$2,999
NT$3,329 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Latta
9.4 out of 10, Exceptional, (532)
"Clean and beautiful, very friendly staff "
claudia
The price is NT$3,780
NT$4,120 total
includes taxes & fees
Dec 17 - Dec 18
Baymont by Wyndham Santee
Santee
8.0 out of 10, Very Good, (1407)
"The best stay"
Terez
The price is NT$2,343
NT$2,600 total
includes taxes & fees
Dec 10 - Dec 11
Comfort Inn & Suites Florence Center Area
Florence
9.2 out of 10, Wonderful, (1160)
"Enjoyed our stay there. "
Cathy
The price is NT$3,160
NT$3,539 total
includes taxes & fees
Dec 28 - Dec 29
Howard Johnson by Wyndham Florence
Florence
8.8 out of 10, Excellent, (2486)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
Timothy
The price is NT$1,936
NT$2,169 total
includes taxes & fees
Dec 15 - Dec 16
Hampton Inn & Suites Florence-North-I-95
Florence
9.0 out of 10, Wonderful, (809)
"Clean room, courteous staff and easy access to and from highway."
Joe
The price is NT$3,293
NT$3,688 total
includes taxes & fees
Dec 16 - Dec 17
Fairfield Inn & Suites by Marriott Santee
Santee
9.8 out of 10, Exceptional, (1003)
"Clean, friendly staff, new, good value"
Robert
The price is NT$3,780
NT$4,196 total
includes taxes & fees
Dec 15 - Dec 16
Inn on the Square, an Ascend Collection Hotel
Uptown Greenwood
9.2 out of 10, Wonderful, (708)
"It was a very clean and beautiful lace to stay. We were there for our honeymoon "
Tracy
The price is NT$3,406
NT$3,781 total
includes taxes & fees
Jan 4 - 2026/1/5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top South Carolina Midlands Hotel Reviews
Graduate by Hilton Columbia SC
10/10 Excellent
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Hotels near popular South Carolina Midlands Attractions
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Carowinds Theme Park
- Hotels near Riverbanks Zoo and Garden
- Hotels near Lake Murray
- Hotels near Colonial Life Arena
- Hotels near Williams Brice Stadium
- Hotels near Florence Civic Center
- Hotels near Township Auditorium
- Hotels near Darlington Raceway
South Carolina Midlands Hotels by Star Rating
Explore more hotels
- Tru By Hilton Columbia Greystone
- Park Inn by Radisson Florence, SC
- La Quinta Inn by Wyndham Columbia NE/Fort Jackson
- Comfort Inn & Suites Florence Center Area
- Springhill Suites by Marriott Columbia near Fort Jackson
- Courtyard by Marriott Columbia Northeast/Fort Jackson Area
- Hyatt Place Columbia/Harbison
- Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
- Country Inn & Suites by Radisson, Columbia, SC
- Courtyard by Marriott Columbia Downtown at USC
- Comfort Suites Columbia at Harbison
- Marriott Columbia
- Hyatt Place Columbia/Downtown/The Vista
- Tru By Hilton Santee
- Hyatt Place Florence Downtown
- Holiday Inn Columbia - Downtown by IHG
- Hampton Inn Columbia-I-26 Airport
- Baymont by Wyndham Santee
- Clarion Pointe Rock Hill Near University
- Spark by Hilton Rock Hill
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