Find Boutique Hotels in South Carolina Midlands, SC

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Check availability on South Carolina Midlands Boutique Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Top South Carolina Midlands Boutique Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in South Carolina Midlands

Lobby
Tru By Hilton Santee

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (627)
"Nice place to stay"
Canada
Tanya
The price is NT$2,974
NT$3,301 total
includes taxes & fees
Dec 14 - Dec 15
Tru By Hilton Santee
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

2.5 star property
Latta
9.4 out of 10, Exceptional, (529)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is NT$3,686
NT$4,018 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express & Suites Latta by IHG
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1407)
"The best stay"
United States
Terez
The price is NT$2,343
NT$2,600 total
includes taxes & fees
Dec 8 - Dec 9
Baymont by Wyndham Santee
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1158)
"Enjoyed our stay there. "
United States
Cathy
The price is NT$3,137
NT$3,514 total
includes taxes & fees
Jan 4 - 2026/1/5
Comfort Inn & Suites Florence Center Area
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2479)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is NT$1,940
NT$2,173 total
includes taxes & fees
Dec 8 - Dec 9
Howard Johnson by Wyndham Florence
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (809)
"Clean room, courteous staff and easy access to and from highway."
United States
Joe
The price is NT$3,324
NT$3,723 total
includes taxes & fees
Jan 6 - 2026/1/7
Hampton Inn & Suites Florence-North-I-95
Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1002)
"Clean, friendly staff, new, good value"
United States
Robert
The price is NT$3,780
NT$4,196 total
includes taxes & fees
Dec 14 - Dec 15
Fairfield Inn & Suites by Marriott Santee
Property entrance
Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel

3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (707)
"It was a very clean and beautiful lace to stay. We were there for our honeymoon "
United States
Tracy
The price is NT$3,412
NT$3,788 total
includes taxes & fees
Jan 4 - 2026/1/5
Inn on the Square, an Ascend Collection Hotel
Lobby
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1005)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is NT$3,224
NT$3,578 total
includes taxes & fees
Dec 14 - Dec 15
Tru by Hilton Orangeburg
Property amenity
Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG

3.0 star property
Lexington
9.2 out of 10, Wonderful, (1002)
"Room was great staff was great"
United States
Stephen
The price is NT$2,996
NT$3,326 total
includes taxes & fees
Dec 13 - Dec 14
Lexington Expo Hotel by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Carolina Midlands Hotel Reviews

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

10/10 Excellent
"Everything was wonderful! Staff, parking, location, bar, and pillows !"
Elizabeth 1-night trip
Posted 3 days ago
Graduate by Hilton Columbia SC

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