Find hotels in Santa María, Oaxaca from NT$1,125

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Tonight
Dec 12 - Dec 13
Tomorrow
Dec 13 - Dec 14
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Our top choices for Santa María hotels

Exterior
One Oaxaca Centro Hotel

One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
Ruta Independencia, 2.5 km from Santa María
8.8 out of 10, Excellent, (1001)
"Very good hotel"
United States
Hugo
The price is NT$2,496
NT$2,970 total
includes taxes & fees
Dec 13 - Dec 14
One Oaxaca Centro Hotel
Building design
Quinta Real Oaxaca

Quinta Real Oaxaca

Quinta Real Oaxaca
4.5 star property
Ruta Independencia, 1.9 km from Santa María
9.6 out of 10, Exceptional, (1000)
"We loved everything about our stay at Quinta Real in Oaxaca, highly recommend, would definitely stay again!"
United States
Valerie
The price is NT$9,283
NT$11,047 total
includes taxes & fees
Dec 14 - Dec 15
Quinta Real Oaxaca
Breakfast area
Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca
3.0 star property
Ruta Independencia, 2 km from Santa María
7.8 out of 10, Good, (195)
"You can walk around downtown "
United States
GORGONIO
The price is NT$1,390
NT$1,807 total
includes taxes & fees
Jan 11 - 2026/1/12
Capital O Posada La Casa De La Tia, Oaxaca
Courtyard
Hotel Hacienda

Hotel Hacienda

Hotel Hacienda
3.5 star property
3.1 km from Santa María
9.0 out of 10, Wonderful, (1007)
"Super friendly and helpful staff, clean room and very good food at the restaurant!!!"
Mexico
Carlos
The price is NT$1,756
NT$2,090 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Hacienda
Classic Room, Non Smoking, Private Bathroom | In-room safe, free WiFi, bed sheets
LePetit

LePetit

LePetit
2.5 star property
Ruta Independencia, 2.2 km from Santa María
9.4 out of 10, Exceptional, (22)
"The staff is amazing"
United States
Carmen
The price is NT$2,122
NT$2,525 total
includes taxes & fees
Dec 13 - Dec 14
LePetit
Terrace/patio
Happy Express Hotel

Happy Express Hotel

Happy Express Hotel
2.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (320)
"Nice and clean close to everything easy walking Quiet, comfortable bed and pillows "
United States
MIRIAM
Happy Express Hotel
Sundeck
Hotel Victoria Oaxaca

Hotel Victoria Oaxaca

Hotel Victoria Oaxaca
3.5 star property
0.8 km from Santa María
8.8 out of 10, Excellent, (1002)
"Good breakfast at the restaurant. Nice setting. Friendly front desk staff."
Canada
David
The price is NT$2,412
NT$2,870 total
includes taxes & fees
Dec 18 - Dec 19
Hotel Victoria Oaxaca
Terrace/patio
Casa de los Frailes Hotel

Casa de los Frailes Hotel

Casa de los Frailes Hotel
3.0 star property
Ruta Independencia, 1.9 km from Santa María
9.2 out of 10, Wonderful, (364)
"Good location close to the centre but on a fairly quiet street. Large rooms, decent shower. "
United Kingdom
Richard
The price is NT$2,421
NT$2,881 total
includes taxes & fees
Dec 14 - Dec 15
Casa de los Frailes Hotel
Indoor spa tub
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca
5.0 star property
Ruta Independencia, 2 km from Santa María
9.6 out of 10, Exceptional, (667)
"Great staff, beautiful rooms, wonderful food. Also perfect location."
United States
John Lester
The price is NT$6,770
NT$8,056 total
includes taxes & fees
Dec 15 - Dec 16
Grand Fiesta Americana Oaxaca
Exterior
Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique
3.5 star property
Reforma, 1.8 km from Santa María
9.4 out of 10, Exceptional, (267)
"Nice staff and huge room with all the amenities."
United States
Celia
The price is NT$2,276
NT$2,708 total
includes taxes & fees
Dec 18 - Dec 19
Casa Los Cantaros Hotel Boutique
Front of property
Casa De Sierra Azul

Casa De Sierra Azul

Casa De Sierra Azul
3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (898)
"Hospitality was the best. Great location with a lot of shops and Zocalo at walkable distance. rooms were beautiful and comfortable "
United States
Brian
Casa De Sierra Azul
Reception
Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel
2.0 star property
2.5 km from Santa María
7.2 out of 10, Good, (106)
"Staff was friendly, & helpful. The location was perfect! Everything was in walking distance, but if you needed a cab the hotel gladly arranged one for you. "
United States
Daisy
The price is NT$945
NT$1,125 total
includes taxes & fees
Dec 17 - Dec 18
Marqués Oaxaca - Hotel
Terrace/patio
Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel
3.0 star property
Ruta Independencia, 1.8 km from Santa María
9.4 out of 10, Exceptional, (778)
"Was one of the best hotels, clean the people were awesome and helped whenever needed"
United States
Asokaraj
The price is NT$4,038
NT$4,805 total
includes taxes & fees
Jan 7 - 2026/1/8
Hotel Boutique Parador San Miguel
Lobby
Hotel Trebol

Hotel Trebol

Hotel Trebol
3.0 star property
Oaxaca Centro, 2.1 km from Santa María
9.2 out of 10, Wonderful, (1009)
"Amazing staff and accommodations will be coming back"
United States
Christopher Joel Romo
The price is NT$3,654
NT$4,348 total
includes taxes & fees
Jan 12 - 2026/1/13
Hotel Trebol
Terrace/patio
Hotel Danibaan

Hotel Danibaan

Hotel Danibaan
3.0 star property
Del Ex-marquezado, 1.1 km from Santa María
9.4 out of 10, Exceptional, (170)
"Clean Gustavo and staff were very nice and i slept so well. It felt like home away from home. "
United States
Marisol
The price is NT$1,730
NT$2,058 total
includes taxes & fees
Dec 13 - Dec 14
Hotel Danibaan
Courtyard
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (980)
"wonderful staff and great amenities. Delicious food in their restaurant + cafe."
United States
Edna
The price is NT$3,075
NT$3,660 total
includes taxes & fees
Jan 7 - 2026/1/8
Hotel Boutique Naura Centro
35-inch flat-screen TV with cable channels
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS
2.0 star property
Oaxaca Centro, 2 km from Santa María
9.0 out of 10, Wonderful, (193)
"It was a quiet place."
United States
Consuelo
The price is NT$1,052
NT$1,252 total
includes taxes & fees
Jan 10 - 2026/1/11
HOTEL POSADA DON MATIAS
Hallway
Casa Antonieta

Casa Antonieta

Casa Antonieta
3.5 star property
Oaxaca Centro, 2.1 km from Santa María
10.0 out of 10, Exceptional, (59)
"A lovely spot all around. "
Canada
Kelly
The price is NT$11,325
NT$13,477 total
includes taxes & fees
Jan 12 - 2026/1/13
Casa Antonieta
Reception
Hotel Real Alma

Hotel Real Alma

Hotel Real Alma
3.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (407)
"Cozy and comfortable hotel. Very clean and staff was very nice and friendly ready to help you with any questions."
United States
Julia
The price is NT$2,658
NT$3,163 total
includes taxes & fees
Jan 8 - 2026/1/9
Hotel Real Alma
Terrace/patio
Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
San Felipe del Agua, 3.1 km from Santa María
9.0 out of 10, Wonderful, (177)
"Hotel was very clean, great food, and very friendly staff! "
United States
ANGELICA
Casa de Adobe Gallery & Luxury Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most.
Oaxaca which includes a city
Photo by PhotoJoy
Open Photo by PhotoJoy

Oaxaca Centro

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Ruta Independencia

If you're spending some time in Ruta Independencia, Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are top sights worth seeing.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

If you're spending some time in Reforma, Plaza Mazari and Plaza Parque are top sights worth seeing.

San Agustín Yatareni

While there might not be top attractions in San Agustín Yatareni, you can explore the larger area and discover places like El Llano Park and Oaxaca Ethnobotanical Garden.

Top Santa María Hotel Reviews

Quinta Real Oaxaca

Quinta Real Oaxaca

10/10 Excellent
"This hotel has so much history - it was once a convent. The staff was wonderful and friendly and helpful. And the location is ideal, with markets and restaurants all walkable. Totally recommend!"
Hilary 2-night trip
Posted 4 days ago
Quinta Real Oaxaca

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Frequently asked questions

What is Santa María like?
Travelers to the Santa María neighborhood in Oaxaca will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santa María, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best options available in Santa María.
Where can I learn more about changing or cancelling my trip to Santa María?
For additional details about rescheduling or cancelling your trip to Santa María, head over to our customer service page.
What is there to do in this Oaxaca neighborhood?
Cerro del Fortín, Parque Juarez El Llano, and Auditorio Guelaguetza are just a few of the places to visit in and around Santa María. While you're out sightseeing in Oaxaca, be sure to visit other sights like Ex-Convento de Santa Catalina or El Mirador.