Find hotels in Santa Cruz from NT$1,108

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Dec 24 - Dec 25
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Dec 25 - Dec 26
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Dec 26 - Dec 28
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Our top choices for Santa Cruz hotels

Luxury Suite | Private spa tub
Hotel Attic 33

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles
9.6 out of 10, Exceptional, (13)
"Was great, very recommended for a quick trip. "
United States
jorge
The price is NT$1,552
NT$1,552 total
Jan 11 - 2026/1/12
Hotel Attic 33
Reception
Hotel Once22

Hotel Once22

Hotel Once22
3.0 star property
Sabaneta
9.6 out of 10, Exceptional, (31)
Located in Sabaneta, this welcoming hotel offers complimentary local cuisine breakfast and WiFi. Just a 14-minute walk to Sabaneta Station and a short drive to popular shopping destinations, with 24-hour front desk service for convenient travel support.
"Great stay as usual, wonderful service from check-in to check-out"
United States
Al
The price is NT$2,069
NT$2,069 total
Jan 13 - 2026/1/14
Hotel Once22
Terrace/patio
Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (243)
Located minutes from Sabaneta Station, this hotel offers convenient access to Santafé Mall and Oviedo Shopping Center. Enjoy 2 restaurants including Restaurante Fairfield, plus a bar, terrace, and snack bar/deli. Free breakfast, WiFi and parking enhance your stay.
"great location "
United States
Juliana
The price is NT$2,269
NT$2,269 total
Jan 9 - 2026/1/10
Fairfield by Marriott Medellin Sabaneta
Coffee shop
ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
3.0 star property
Itagüí
9.0 out of 10, Wonderful, (404)
This Itagüí hotel offers convenient access to Oviedo Shopping Center and Medellín Clinic within a 10-minute drive. Enjoy complimentary WiFi and self parking, plus nearby hiking trails. Sabaneta Station is just 3 minutes away for easy city exploration.
"Great location with clean rooms!"
United States
Camila
The price is NT$1,425
NT$1,425 total
Dec 28 - Dec 29
ibis budget Medellín Itagüí Metro
Lobby sitting area
Arame Hotel

Arame Hotel

Arame Hotel
3.0 star property
Envigado
9.2 out of 10, Wonderful, (176)
"Friendly and helpful the food was top notch as well as the service. "
United States
August
The price is NT$2,593
NT$2,593 total
Dec 30 - Dec 31
Arame Hotel
Interior
4 Sur Hotel

4 Sur Hotel

4 Sur Hotel
3.0 star property
Guayabal
9.4 out of 10, Exceptional, (200)
Vibrant hotel in El Poblado featuring complimentary breakfast and free WiFi. Just minutes from Oviedo Shopping Center and Santafé Mall, with Poblado Station a short walk away. The 24-hour fitness center and friendly staff ensure a comfortable business stay.
"Very good place to enjoy the stay"
United States
Alberto
The price is NT$2,205
NT$2,306 total
Dec 26 - Dec 27
4 Sur Hotel
Building design
Hotel Nutibara

Hotel Nutibara

Hotel Nutibara
3.0 star property
La Candelaria
7.4 out of 10, Good, (538)
Immerse yourself in downtown Medellín at this hotel with 3 restaurants and 2 bars. Just 3 minutes from Parque Berrio Station and a short drive to Botero Plaza and Poblado Park. Business travelers appreciate the free breakfast and helpful staff.
"Good, staff very friendley. "
United States
Robert
The price is NT$2,674
NT$2,674 total
Jan 23 - 2026/1/24
Hotel Nutibara
Panoramic Loft, 2 Twin Beds | View from room
Firenze Lofts

Firenze Lofts

Firenze Lofts
3.0 star property
La América
9.6 out of 10, Exceptional, (378)
Located in Medellín, these smart apartments offer full kitchens and complimentary WiFi. Just 5 minutes from Plaza Mayor Convention Center and an 8-minute walk to Floresta Station, this convenient spot places you near Atanasio Giradot Stadium and Pueblito Paisa.
"Great place, quiet, clean and the staff was nice "
United States
maria
Firenze Lofts
Restaurant
Nakúa Stay + Work

Nakúa Stay + Work

Nakúa Stay + Work
2.5 star property
El Poblado
9.4 out of 10, Exceptional, (117)
Enjoy a welcoming atmosphere at this central Medellín hotel within a 10-minute stroll of popular parks. Free WiFi keeps you connected while the attentive 24-hour staff ensures a hassle-free stay. Nearby El Tesoro Shopping Park offers retail therapy.
"Everything was great . Clean "
United States
Gilberto
The price is NT$2,052
NT$2,052 total
Dec 28 - Dec 29
Nakúa Stay + Work
Outdoor pool
Los Patios Cool Living

Los Patios Cool Living

Los Patios Cool Living
3.0 star property
Laureles
9.4 out of 10, Exceptional, (433)
Discover stylish comfort at this Medellin hotel with 2 restaurants and outdoor pool. Just minutes from Plaza Mayor Convention Center and Botero Plaza, enjoy free breakfast, WiFi, poolside bar and sauna. Guests consistently praise the helpful staff and clean accommodations.
"Awesome hotel and staff!"
United States
Josh
Los Patios Cool Living
Superior Double Room, 1 Queen Bed | Minibar, in-room safe, desk, blackout drapes
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (298)
Tropical ambiance awaits at this family-friendly hotel featuring outdoor and children's pools. Located near Complex Llanogrande Shopping Center and mall, guests enjoy free breakfast, WiFi, and parking. The helpful staff receives consistent praise from travelers.
"Nice property, very good food, very relaxing."
United States
Kevin
The price is NT$3,951
NT$3,951 total
Dec 26 - Dec 27
Hotel Lagoon
Exterior
La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1004)
Located near Poblado Park, this hotel offers a refreshing outdoor pool with poolside bar. Enjoy complimentary breakfast, WiFi, and parking while staying just minutes from Lleras Park and Industriales Station. In-room refrigerators and microwaves add extra convenience.
"Breakfast, clean room and room service amazing!"
United States
Lyandra Jiliénne
The price is NT$2,651
NT$2,651 total
Jan 12 - 2026/1/13
La Quinta by Wyndham Medellin
Snack bar
The Host Medellin Only Adults

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
9.8 out of 10, Exceptional, (13)
Exclusive adults-only hotel near Poblado and Lleras Park. Enjoy complimentary breakfast before exploring El Poblado's attractions. Unwind at the on-site restaurant and bar after a day of adventure, with Poblado Station just 12 minutes away.
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is NT$6,876
NT$6,876 total
Dec 27 - Dec 28
The Host Medellin Only Adults
Rooftop terrace
York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton

York Medellin, Curio Collection by Hilton
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (1424)
Located minutes from Oviedo Shopping Center and Santafé Mall, this Medellín aparthotel features indoor and outdoor pools. The apartments offer Egyptian cotton sheets on Tempur-Pedic beds and designer toiletries. Enjoy the restaurant, spa services, and free WiFi while staying close to Aguacatala Station.
"Great place to stay !"
United States
Lendsey
The price is NT$4,521
NT$4,521 total
Jan 4 - 2026/1/5
York Medellin, Curio Collection by Hilton
Terrace/patio
Landmark Hotel

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (229)
This Medellín hotel offers a refreshing outdoor pool and relaxing hot tub experience just 15 minutes from Poblado Park and Lleras Park. Enjoy the coffee shop, bar, and poolside drinks, with Poblado Station only 11 minutes away.
"Very nice hotel. "
United States
Andres F.
The price is NT$4,315
NT$4,315 total
Jan 13 - 2026/1/14
Landmark Hotel
Standard Double Room, City View | Minibar, in-room safe, individually decorated, individually furnished
Moa Select

Moa Select

Moa Select
3.0 star property
Laureles
9.2 out of 10, Wonderful, (201)
Discover cultural attractions from this Medellín hotel, just a short drive from Plaza Mayor and Botero Plaza. Enjoy complimentary full breakfast each morning and convenient WiFi access. The 24-hour front desk ensures assistance is always available for your adventures.
"Great place"
United States
Cody
The price is NT$1,514
NT$1,514 total
Jan 20 - 2026/1/21
Moa Select
Design Studio Suite, 1 Queen Bed, Non Smoking, Kitchenette | Living area | 43-inch Smart TV with cable channels, TV
Indie Universe Creative Hotel

Indie Universe Creative Hotel

Indie Universe Creative Hotel
2.5 star property
Laureles
8.4 out of 10, Very Good, (149)
Enjoy creative surroundings just minutes from Plaza Mayor Convention Center and Botero Plaza. Start each day with complimentary breakfast before exploring nearby Pueblito Paisa. The 24-hour front desk and helpful staff ensure a comfortable stay while Estadio Station is a short walk away.
"Great servace"
United States
Mark
Indie Universe Creative Hotel
Exterior
Holiday Inn Express Medellin by IHG

Holiday Inn Express Medellin by IHG

Holiday Inn Express Medellin by IHG
3.0 star property
El Poblado
8.8 out of 10, Excellent, (925)
Located just minutes from Oviedo Shopping Center and Santafé Mall, this hotel offers convenient amenities including daily continental breakfast and complimentary WiFi. A fitness center awaits after exploring nearby Poblado Park, while free parking adds value to your Colombian adventure.
"Great!"
United States
Kelly
The price is NT$2,962
NT$3,434 total
Jan 9 - 2026/1/10
Holiday Inn Express Medellin by IHG
Restaurant
Hunters By Jalo

Hunters By Jalo

Hunters By Jalo
3.0 star property
El Poblado
9.0 out of 10, Wonderful, (213)
Set in a prime location, this hotel offers easy access to Medellín's social hotspots. Wander to Lleras Park for nightlife or relax in Poblado Park, with El Tesoro and Oviedo shopping centers just 5 minutes away by car. Free WiFi enhances your stay.
"Really nice hotel! "
United States
IBRAHIM
The price is NT$1,888
NT$1,888 total
Jan 8 - 2026/1/9
Hunters By Jalo
Breakfast, lunch, dinner served; Italian cuisine
Hotel Santiago de Arma

Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (914)
Experience Italian meals at La Cucina de la Italia, enjoy free breakfast, WiFi, and parking at this convenient hotel. With a garden and terrace plus bar, it's praised for helpful staff and proximity to MDE airport and Llanogrande Mall.
"Very clean room and very friendly staff."
United States
Redding
Hotel Santiago de Arma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Solid choice in Poblado. "
ryan s. 4-night trip
Posted 1 day ago
Dann Carlton Medellin Hotel

More cheap stays in Santa Cruz

Hotel Villanueva Comfort

Hotel Villanueva Comfort

57-12 Cra. 49 Medellín Antioquia
The price is NT$1,108 per night from Dec 26 to Dec 27
NT$1,108
NT$1,108 total
Dec 26 - Dec 27
8.6/10 Excellent! (29 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 5.9 mi (9.4 km) from the heart of Santa Cruz, Heiss Hotel By Jalo is a top choice for your stay based on our traveler data. Other good choices for your trip to the area are Calle Flora Hotel by Jalo and Hotel Dorado La 70. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
La Gracia Hotel & Spa: This vacation home rental near Santa Cruz offers a terrace, a garden, and free WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
For additional details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What is staying in Santa Cruz like?
Visitors are sure to enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 3 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What are the top places to visit in Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Parque Fabricato Shopping Center, and Arvi Park. You'll also find Antioquia Museum and Botero Plaza in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Head over to Andalucía MetroCable Station for metro transit. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually August and July with an average temp of 66°F, while the coldest months are December and January with an average of 64°F. The rainiest months in Santa Cruz are May, April, October, and November, with each month seeing an average of 16 inches of rainfall.