The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A large, two-story building with a prominent entrance, multiple windows, and a well-maintained garden.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

NT$4,873

NT$5,592 total

includes taxes & fees

Oct 26 - Oct 27

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A historic building with a prominent tower and a traditional brick facade.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

NT$10,377

NT$12,066 total

includes taxes & fees

Oct 6 - Oct 7

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Barbara

NT$4,110

NT$5,660 total

includes taxes & fees

Oct 11 - Oct 12

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

4. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

NT$6,280

NT$7,206 total

includes taxes & fees

Oct 18 - Oct 19

A two-story building with a white exterior, a red door, and large windows.

A hot tub with a wooden fence and a brick building in the background.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

5. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

NT$5,544

NT$6,362 total

includes taxes & fees

Oct 6 - Oct 7

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

6. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Janet

NT$8,368

NT$9,770 total

includes taxes & fees

Nov 3 - Nov 4

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.

A modern kitchen with a central island, bar stools, and built-in appliances.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

7. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

Vincent

NT$7,714

NT$9,006 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel lobby with a bar area, seating, and a large TV screen.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a glass-enclosed area.

A modern restaurant with a long counter, bar stools, and a refrigerated display.

A modern building with a Starbucks on the ground floor, featuring large windows and a flat roof.

8. Residence Inn by Marriott Buffalo Downtown

Allentown, 0.7 km from Roswell Park Cancer Institute

Karen

NT$7,556

NT$8,821 total

includes taxes & fees

Oct 12 - Oct 13

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

9. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Julian

NT$5,019

NT$5,859 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

The Westin hotel entrance with a glass facade and a sign indicating it's now open.

An outdoor patio area with seating, a fire feature, and a glass-enclosed space with greenery.

A gym with treadmills and a rowing machine, large windows, and a city view.

10. The Westin Buffalo

Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute

Sarah

NT$7,551

NT$8,816 total

includes taxes & fees

Oct 18 - Oct 19

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

11. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

NT$7,285

NT$8,505 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A modern kitchen with a central island, bar stools, and various appliances.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

12. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

John

NT$4,846

NT$5,658 total

includes taxes & fees

Oct 19 - Oct 20

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

A breakfast buffet with various pastries, fruits, and bread.

13. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Frank

NT$5,416

NT$6,324 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

A lobby area with a reception desk, seating arrangements, a coffee station with beverages and snacks, and a decorative wall with a fireplace.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

14. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

NT$5,118

NT$5,976 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A brick building with a storefront labeled 'FRIDAYS' and a green sign with a white 'H' indicating a Holiday Inn Express & Suites.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

Michael

NT$4,174

NT$4,873 total

includes taxes & fees

Oct 15 - Oct 16

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A modern bar area with seating, a counter with bottles, and a large window.

A modern hotel room with a dining area, a large bed, and a view of the city.

A conference room with two chairs and a table, large windows with a city view, and a patterned carpet.

16. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Michelle

NT$5,660

NT$6,608 total

includes taxes & fees

Oct 18 - Oct 19

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

A modern hotel room with a fireplace, a flat-screen TV, a sofa, and a bed.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

17. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Angela

NT$4,929

NT$5,755 total

includes taxes & fees

Oct 18 - Oct 19

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

A grand staircase with a decorative railing and a Christmas tree adorned with ornaments and ribbons.

A casino interior with slot machines, a large illuminated pillar, and comfortable seating areas.

A traditional living room with a wooden floor, a sofa, a coffee table, and a fireplace.

18. Summer Street Guest House

Bryant, 1.3 km from Roswell Park Cancer Institute

Anthony

NT$11,441

NT$16,785 total

includes taxes & fees

Oct 6 - Oct 7

A lobby with a staircase, seating area, and a view of the outdoors.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

A hotel with a classic brick facade, a glass entrance, and flags.

A bathroom with a toilet, sink, and shower curtain.

19. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Richarda

NT$3,097

NT$3,554 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

20. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Joseph

NT$4,363

NT$5,094 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 55 reviews	View
The Edward Hotel	9.6 Exceptional 266 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,001 reviews	View
Buffalo Guesthouse	9.4 Exceptional 216 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

Buffalo Guesthouse

10/10 Excellent

"Cleanliness was a ten- Staff was exceptional. Breakfast was home-cooked and plentiful. Very pleasant stay just minutes to town."

The Mansion On Delaware Ave

8/10 Good

"Nice hotel, shower needs an update"

Embassy Suites Buffalo

10/10 Excellent

"Very good experience, would highly recommend this property and great location. Rooms very nicely appointed, and they allowed early check-in without any grief. Nice bar and restaurant attached. with a small self-check store/coffee stand."

Lenox Hotel and Suites

10/10 Excellent

"We really enjoyed this property. Obviously it's an old building but very enjoyable experience."

Hilton Garden Inn Buffalo Downtown

10/10 Excellent

"Everything was great! Clean room, friendly staff."

Hotel at the Lafayette Trademark Collection by Wyndham

10/10 Excellent

"The rooms are large and so unique. Mine had a lovely living room, separated from the bedroom by steps, a partial wall and two-sided fireplace (though, tbh, the 'fire' was comically fake). Still, it was a fun detail. Art Deco decorations, furnishings and colors, wide hallway, large bathroom. Patient and kind staff who gave delightful advice for making the most of my time in Buffalo. It is full of history, and my only wish was that more of the main floor was restored and open. Highly recommend. Also, half a block from The Lunch Box bakery, which has fantastic coffee."

Best Western on the Avenue

8/10 Good

"na"

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Friendly staff, excellent breakfast buffet, convenient location. I would definitely stay here again."

Buffalo Harmony House

10/10 Excellent

"Beautiful place. Great breakfasts. Wonderful staff."

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from NT$3,554

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. The Mansion On Delaware Ave

5. Buffalo Guesthouse

6. Curtiss Hotel, an Ascend Collection Hotel

7. Buffalo Marriott at LECOM HARBORCENTER

8. Residence Inn by Marriott Buffalo Downtown

9. Wyndham Garden Buffalo Downtown

10. The Westin Buffalo

11. Courtyard Buffalo Downtown / Canalside

12. Best Western on the Avenue

13. Hampton Inn & Suites Buffalo Downtown

14. Hilton Garden Inn Buffalo Downtown

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

16. Embassy Suites Buffalo

17. Hotel at the Lafayette Trademark Collection by Wyndham

18. Summer Street Guest House

19. Lenox Hotel and Suites

20. Hyatt Regency Buffalo / Hotel and Conference Center

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

Buffalo Guesthouse

The Mansion On Delaware Ave

Embassy Suites Buffalo

Lenox Hotel and Suites

Hilton Garden Inn Buffalo Downtown

Hotel at the Lafayette Trademark Collection by Wyndham

Best Western on the Avenue

Residence Inn by Marriott Buffalo Downtown

Buffalo Harmony House

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions

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