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Our top choices for Penrose hotels

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Best Western Plus The Charles Hotel
Best Western Plus The Charles Hotel
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
Hampton Inn & Suites St. Louis/Alton
Hampton Inn & Suites St. Louis/Alton
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
Sonesta Simply Suites St Louis Earth City
Sonesta Simply Suites St Louis Earth City
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Motel 6 Hazelwood, MO
Motel 6 Hazelwood, MO
The Principal Hotel
The Principal Hotel
Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. Louis
Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis Airport
Drury Inn & Suites St. Louis Collinsville
Drury Inn & Suites St. Louis Collinsville
SpringHill Suites by Marriott St. Louis Airport/Earth City
SpringHill Suites by Marriott St. Louis Airport/Earth CityWhere to stay in Penrose

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
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