San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo
Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Popular places to visit


San Francisco Hotel Deals

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is NT$4,055 per night from Apr 3 to Apr 4
NT$4,055
NT$4,461 total
Apr 3 - Apr 4
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,005 reviews)
The hotel is a bit off the main areas, need to use uber to get to downtown. Other than that, every thing was awesome. this was a birthday trip, so I mentioned its my birthday and was given some delicious deserts. That was an awesome gesture. Thank you Sheraton for making my birthday extra ...

Reviewed on 2026/3/13

Sheraton Grand Panama
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is NT$3,062 per night from Mar 27 to Mar 28
NT$3,062
NT$3,368 total
Mar 27 - Mar 28
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,150 reviews)
Very good location. Kind staff as well.

Reviewed on 2026/3/14

Ramada Plaza by Wyndham Panama Punta Pacifica
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is NT$7,865 per night from Apr 5 to Apr 6
NT$7,865
NT$8,652 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
Very enjoyable stay

Reviewed on 2026/3/12

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is NT$3,375 per night from Apr 11 to Apr 12
NT$3,375
NT$3,712 total
Apr 11 - Apr 12
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,003 reviews)
The room was cleaned everyday the staff was helpful

Reviewed on 2026/3/14

Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is NT$5,347 per night from Apr 12 to Apr 13
NT$5,347
NT$5,882 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,000 reviews)
Great central location in PC with very nice accommodations.

Reviewed on 2026/3/13

Las Americas Golden Tower Panama
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is NT$3,592 per night from Mar 21 to Mar 22
NT$3,592
NT$3,952 total
Mar 21 - Mar 22
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (986 reviews)
Convenient location, great bakery inside, offers adjoining room for family

Reviewed on 2026/3/14

Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

4/5(91 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

4/5(368 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

5/5(2 area reviews)

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


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