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Our top choices for Panama City hotels with a casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1848)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is NT$3,931
NT$4,324 total
includes taxes & fees
Jan 18 - 2026/1/19
Riande Aeropuerto Hotel & Casino

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is NT$11,092
NT$12,201 total
includes taxes & fees
Jan 5 - 2026/1/6
Hotel La Compañía Casco Antiguo

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1002)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is NT$10,345
NT$11,379 total
includes taxes & fees
Jan 3 - 2026/1/4
JW Marriott Panama

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1000)
"Great hotel and staff!"
United States
Catherine
The price is NT$5,061
NT$5,567 total
includes taxes & fees
Jan 2 - 2026/1/3
Marriott Panama Hotel

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Nice room! Clean. Nice balcony, "
United States
Cassandra
The price is NT$6,335
NT$6,969 total
includes taxes & fees
Jan 3 - 2026/1/4
Hilton Panama

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1312)
"Clean convenient beautiful hotel. "
United States
Daniel
The price is NT$8,342
NT$9,177 total
includes taxes & fees
Jan 2 - 2026/1/3
Megapolis Hotel Panamá

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
Tocumen
9.0 out of 10, Wonderful, (39)
"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is NT$3,772
NT$4,896 total
includes taxes & fees
Jan 26 - 2026/1/27
ORHO HOTEL BOUTIQUE PANAMA Airport

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1464)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is NT$4,421
NT$4,864 total
includes taxes & fees
Jan 3 - 2026/1/4
Decapolis Hotel Panama City

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is NT$4,999
NT$5,499 total
includes taxes & fees
Jan 3 - 2026/1/4
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1004)
"Location Location Location! Clean, safe, beautiful. Loved it!"
United States
Sharon Gobern Dorray and Jason
The price is NT$3,448
NT$3,792 total
includes taxes & fees
Jan 12 - 2026/1/13
Courtyard by Marriott Panama Metromall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Searching for casino hotels in Panama City?
Hoping to do some gaming in Panama City? You're in luck, because you'll find Crown Casino, Fiesta Casino, and Bingo 90 here, as well as lots more to see and do. Tourists speak highly of the local cuisine, fantastic nightlife, and shopping. You might want to visit top attractions like Albrook Shopping Mall.
What's the best hotel to visit the local casinos in Panama City?
Megapolis Hotel Panamá is a top hotel featuring a casino and free stocked minibars. Other good options near the gaming action include Decapolis Hotel Panama City and Hilton Panama.
How many hotels that are good for gaming will I find in Panama City?
Practice your poker face at one of Expedia's 1534 casino hotels in Panama City.
When should I take my casino trip to Panama City?
You'll likely spend much of your trip indoors, but if you're planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.
What is there to do in Panama City?
If you've had a stroke of luck, you can head to Albrook Shopping Mall, Via Espana, or Uruguay Street to spend your winnings. Check out National Theater, Interoceanic Canal Museum, or Biomuseo for a taste of local culture. Additionally, you might consider adding Iglesia del Carmen and Avenida Balboa to your itinerary.
What are my transportation options for my casino getaway to Panama City?
Getting around Panama City is easier with these transportation options: You can fly into the closest airport, which is Panama City (PAC-Marcos A. Gelabert Intl.), 2.5 mi (4 km) from the city center. You can access metro transit at Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. To see more of the larger area, ride aboard one of the trains from Panama City Passenger Station.