Top 10 Hotels in O Brien, FL from NT$2,056 - Competitive Prices

A calm river with clear water, surrounded by dense trees and rocky banks.

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Go beyond your typical stay in O Brien

Pet friendly

Apartment

Pool

Condo

Family friendly

Waterpark

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Our top choices for O Brien hotels

1. Best Western Plus Lake City

Lake City

William

NT$2,561

NT$2,881 total

includes taxes & fees

Sep 6 - Sep 7

2. Hampton Inn & Suites Lake City

Lake City

tracy

NT$3,605

NT$4,055 total

includes taxes & fees

Sep 6 - Sep 7

3. Tru by Hilton Lake City

Lake City

Kelly

NT$3,446

NT$3,877 total

includes taxes & fees

Sep 6 - Sep 7

Suite, Multiple Beds, Accessible, Non Smoking

4. Comfort Suites Lake City

Lake City

KHAJA

NT$2,929

NT$3,295 total

includes taxes & fees

Sep 13 - Sep 14

Studio Suite, 1 King Bed, Non Smoking | Living area

Suite, 1 Bedroom, Non Smoking | Private kitchen

5. Home2 Suites by Hilton Lake City

Lake City

William

NT$3,869

NT$4,353 total

includes taxes & fees

Sep 6 - Sep 7

6. Fairfield Inn & Suites Lake City

Lake City

Thomas

NT$3,244

NT$3,650 total

includes taxes & fees

Sep 6 - Sep 7

7. La Quinta Inn & Suite by Wyndham Lake City

Lake City

Nadia

NT$2,853

NT$3,209 total

includes taxes & fees

Aug 30 - Aug 31

8. Super 8 by Wyndham Lake City

Lake City

Mari

NT$2,069

NT$2,328 total

includes taxes & fees

Sep 1 - Sep 2

9. Holiday Inn Express & Suites Live Oak by IHG

Live Oak

Trisha

NT$3,225

NT$3,548 total

includes taxes & fees

Sep 27 - Sep 28

10. Americas Best Value Inn Lake City

Lake City

Larissa

NT$2,134

NT$2,401 total

includes taxes & fees

Aug 30 - Aug 31

Standard Room, 2 Double Beds, Non Smoking

11. Quality Inn Lake City

Lake City

Lucille

NT$2,311

NT$2,600 total

includes taxes & fees

Sep 27 - Sep 28

12. Days Inn by Wyndham Lake City I-75

Lake City

Brizheet

NT$1,998

NT$2,248 total

includes taxes & fees

Aug 30 - Aug 31

13. Holiday Inn & Suites Lake City by IHG

Lake City

Renee

NT$3,130

NT$3,522 total

includes taxes & fees

Sep 28 - Sep 29

14. Motel 6 – Lake City, Fl – Medical Center

Lake City

Pennee

NT$2,060

NT$2,318 total

includes taxes & fees

Aug 31 - Sep 1

Room, 2 Double Beds, Accessible, Non Smoking

Room, 2 Double Beds, Accessible, Smoking

15. Econo Lodge Live Oak

Live Oak

James

NT$2,319

NT$2,551 total

includes taxes & fees

Aug 31 - Sep 1

16. Quality Inn White Springs Suwanee

White Springs

Pennee

NT$1,902

NT$2,092 total

includes taxes & fees

Aug 30 - Aug 31

17. Regal Inn

Lake City

Samuel

NT$1,962

NT$2,207 total

includes taxes & fees

Sep 1 - Sep 2

18. Driftwood Inn

Lake City

Jamie

NT$1,681

NT$1,891 total

includes taxes & fees

Aug 30 - Aug 31

19. Suwannee River Retreat: Pet Friendly, Private Dock

Branford

NT$10,207

NT$19,219 total

includes taxes & fees

Aug 31 - Sep 1

Room, Multiple Beds, Non Smoking (Oversize)

20. Baymont by Wyndham Lake City I-75

Lake City

Steve

NT$1,828

NT$2,056 total

includes taxes & fees

Sep 1 - Sep 2

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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Fairfield Inn & Suites Lake City

10/10 Excellent

"It was a nice hotel that was close to food and the highway"

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"It was amazing, I loved this trip"

Days Inn by Wyndham Lake City I-10

10/10 Excellent

"Efficiet and cooperative staff. Clean room. Easy parking. Pleasant hotel."

Hampton Inn & Suites Alachua I-75

10/10 Excellent

"N/A"

Quality Inn Lake City

10/10 Excellent

"Very clean and quiet hotel. I will visit again when I am in the area."

Baymont by Wyndham Lake City I-75

10/10 Excellent

"Nice place"

More cheap stays in O Brien

Days Inn by Wyndham Lake City I-10

3430 N Us Highway 441 Lake City FL

NT$1,872

NT$2,106 total

Sep 1 - Sep 2

includes taxes & fees

7/10 Good! (1,000 reviews)

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL

NT$2,311

NT$2,600 total

Sep 27 - Sep 28

includes taxes & fees

8.2/10 Very Good! (1,000 reviews)

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

NT$2,561

NT$2,881 total

Sep 6 - Sep 7

includes taxes & fees

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL

NT$2,929

NT$3,295 total

Sep 13 - Sep 14

includes taxes & fees

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane Alachua FL

NT$3,345

NT$3,763 total

Sep 10 - Sep 11

includes taxes & fees

9.4/10 Exceptional! (552 reviews)

Tru by Hilton Lake City

284 NW Centurion Court Lake City FL

NT$3,446

NT$3,877 total

Sep 6 - Sep 7

includes taxes & fees

Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?

Best Western Plus Lake City, located 17.9 mi (28.8 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and La Quinta Inn & Suite by Wyndham Lake City. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

Best Western Plus Lake City: Provides a snack bar/deli, an indoor pool, and buffet. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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Find hotels in O Brien, FL from NT$2,056

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in O Brien

Check prices for these dates

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Star rating

Guest rating

Our top choices for O Brien hotels

1. Best Western Plus Lake City

2. Hampton Inn & Suites Lake City

3. Tru by Hilton Lake City

4. Comfort Suites Lake City

5. Home2 Suites by Hilton Lake City

6. Fairfield Inn & Suites Lake City

7. La Quinta Inn & Suite by Wyndham Lake City

8. Super 8 by Wyndham Lake City

9. Holiday Inn Express & Suites Live Oak by IHG

10. Americas Best Value Inn Lake City

11. Quality Inn Lake City

12. Days Inn by Wyndham Lake City I-75

13. Holiday Inn & Suites Lake City by IHG

14. Motel 6 – Lake City, Fl – Medical Center

15. Econo Lodge Live Oak

16. Quality Inn White Springs Suwanee

17. Regal Inn

18. Driftwood Inn

19. Suwannee River Retreat: Pet Friendly, Private Dock

20. Baymont by Wyndham Lake City I-75

Learn more about O Brien

Top O Brien Hotel Reviews

Fairfield Inn & Suites Lake City

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Days Inn by Wyndham Lake City I-10

Hampton Inn & Suites Alachua I-75

Quality Inn Lake City

Baymont by Wyndham Lake City I-75

More cheap stays in O Brien

Days Inn by Wyndham Lake City I-10

Quality Inn Lake City

Best Western Plus Lake City

Comfort Suites Lake City

Hampton Inn & Suites Alachua I-75

Tru by Hilton Lake City

Hotels in O Brien with star-rating

Frequently asked questions

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