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Our top choices for Medical District hotels

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown
2.0 star property
Medical District
5.6 out of 10, (1001)
"Room was clean and smelled fresh/sanitized. Hotel is well gated and secured"
United States
Antonio
The price is NT$1,535
NT$1,886 total
includes taxes & fees
Dec 30 - Dec 31
Motel 6 Memphis, TN - Downtown

Capital O Kings Inn

Capital O Kings Inn
2.5 star property
Medical District
5.6 out of 10, (28)
"No room service for an entire week, Will never stay there again. "
United States
Ian
The price is NT$1,527
NT$2,096 total
includes taxes & fees
Dec 30 - Dec 31
Capital O Kings Inn

Comfort Inn Horn Lake - Southhaven

Comfort Inn Horn Lake - Southhaven
2.5 star property
19.4 km from Medical District
8.2 out of 10, Very Good, (605)
"Ideal place for a short stay. I was very pleased!"
United States
Kenya
The price is NT$2,694
NT$2,999 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn Horn Lake - Southhaven

Sleep Inn Horn Lake - Southaven

Sleep Inn Horn Lake - Southaven
2.5 star property
19.8 km from Medical District
7.6 out of 10, Good, (689)
"The stay was very good. Room was clean. Nice location with a lot of amenties in the area. Clean and quiet location. "
Canada
Michael
The price is NT$2,237
NT$2,501 total
includes taxes & fees
Jan 11 - 2026/1/12
Sleep Inn Horn Lake - Southaven

Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites
2.5 star property
Wolfchase, 24.6 km from Medical District
8.0 out of 10, Very Good, (1006)
"Very nice place to stay."
United States
Jack
The price is NT$2,434
NT$2,954 total
includes taxes & fees
Jan 3 - 2026/1/4
Best Western Plus Galleria Inn & Suites

Wingate by Wyndham Horn Lake Southaven

Wingate by Wyndham Horn Lake Southaven
2.0 star property
20 km from Medical District
7.4 out of 10, Good, (581)
"yes , yes , yes would gladly stay again "
United States
Starla
The price is NT$2,378
NT$2,655 total
includes taxes & fees
Jan 4 - 2026/1/5
Wingate by Wyndham Horn Lake Southaven

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland
2.0 star property
19.7 km from Medical District
8.4 out of 10, Very Good, (598)
"Quiet and nice are. The hotel is close to many food and shopping places. The breakfast wasn’t what we expected. No eggs, meat, nor grits. "
United States
Ashley
The price is NT$2,688
NT$2,992 total
includes taxes & fees
Dec 30 - Dec 31
Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Homestay Horn Lake / Southaven MS

Homestay Horn Lake / Southaven MS
2.5 star property
20 km from Medical District
7.2 out of 10, Good, (1001)
"Everything was decent...I was only there as a resting i"
United States
Derrick
The price is NT$2,138
NT$2,393 total
includes taxes & fees
Jan 25 - 2026/1/26
Homestay Horn Lake / Southaven MS

Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria
3.0 star property
Wolfchase, 22.4 km from Medical District
9.0 out of 10, Wonderful, (1381)
"Great breakfast selection, cleanliness "
United States
JACQUE
The price is NT$2,766
NT$3,348 total
includes taxes & fees
Jan 4 - 2026/1/5
Hyatt Place Memphis/Wolfchase Galleria

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG
3.0 star property
Southwind, 24.3 km from Medical District
8.4 out of 10, Very Good, (1002)
"Great stay!!"
United States
Megan
The price is NT$2,200
NT$2,514 total
includes taxes & fees
Jan 4 - 2026/1/5
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven
3.0 star property
20 km from Medical District
9.2 out of 10, Wonderful, (1004)
"Friendly staff, clean room, happy hour food & drink"
United States
Kathleen
The price is NT$3,143
NT$3,489 total
includes taxes & fees
Jan 1 - 2026/1/2
Drury Inn & Suites Memphis Southaven

La Quinta Inn & Suites by Wyndham Memphis Wolfchase

La Quinta Inn & Suites by Wyndham Memphis Wolfchase
3.0 star property
Wolfchase, 24 km from Medical District
8.8 out of 10, Excellent, (1003)
"Clean room, friendly staff."
United States
James
The price is NT$2,912
NT$3,521 total
includes taxes & fees
Dec 30 - Dec 31
La Quinta Inn & Suites by Wyndham Memphis Wolfchase

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.9 km from Medical District
8.8 out of 10, Excellent, (1010)
"Great hotel "
United States
Andre
The price is NT$2,703
NT$3,272 total
includes taxes & fees
Jan 4 - 2026/1/5
Comfort Inn Memphis Downtown

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG
3.0 star property
Wolfchase, 24 km from Medical District
8.8 out of 10, Excellent, (1001)
"Staff is welcome and room is clean and amazing "
United States
Truc
The price is NT$2,924
NT$3,535 total
includes taxes & fees
Dec 29 - Dec 30
Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Hilton Garden Inn Memphis/Wolfchase Galleria

Hilton Garden Inn Memphis/Wolfchase Galleria
3.0 star property
22.1 km from Medical District
8.2 out of 10, Very Good, (1000)
"Love that hotel "
United States
Sherkenna
The price is NT$2,636
NT$3,193 total
includes taxes & fees
Jan 4 - 2026/1/5
Hilton Garden Inn Memphis/Wolfchase Galleria

Fairfield Inn & Suites By Marriott Memphis Germantown

Fairfield Inn & Suites By Marriott Memphis Germantown
2.5 star property
27.1 km from Medical District
8.2 out of 10, Very Good, (1001)
"Warm breakfast Clean pool and hot tub Nice parking "
United States
Glenda
The price is NT$3,176
NT$3,803 total
includes taxes & fees
Dec 29 - Dec 30
Fairfield Inn & Suites By Marriott Memphis Germantown

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.9 km from Medical District
8.4 out of 10, Very Good, (1644)
"Friendly staff, clean rooms, perfect location"
United States
Billy
The price is NT$2,757
NT$3,419 total
includes taxes & fees
Jan 15 - 2026/1/16
Hu. Hotel

Four Points by Sheraton Memphis Southwind

Four Points by Sheraton Memphis Southwind
3.0 star property
Southwind, 24.2 km from Medical District
8.2 out of 10, Very Good, (1001)
"Clean rooms, great breakfast, and super friendly staff."
United States
Kameilah
The price is NT$2,571
NT$2,937 total
includes taxes & fees
Dec 30 - Dec 31
Four Points by Sheraton Memphis Southwind

Hyatt Place Memphis Primacy Park

Hyatt Place Memphis Primacy Park
3.0 star property
16.2 km from Medical District
7.8 out of 10, Good, (1001)
"Great service and breakfast "
United States
Chase
The price is NT$2,923
NT$3,534 total
includes taxes & fees
Jan 4 - 2026/1/5
Hyatt Place Memphis Primacy Park

Memphis Vitality Hotel

Memphis Vitality Hotel
4.0 star property
13.8 km from Medical District
8.4 out of 10, Very Good, (1225)
"Staff was amazing. Room was clean. We enjoyed our stay."
United States
Johnathon
The price is NT$2,739
NT$3,315 total
includes taxes & fees
Dec 30 - Dec 31
Memphis Vitality Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Memphis

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

East Memphis

East Memphis is beloved for its popular shops. Take some time to explore sights in the area like Theatre Memphis and Memphis Botanic Garden.

Midtown

Immerse yourself in the arts scene with institutions like Playhouse on the Square and Brooks Museum of Art, or explore Overton Park's Memphis Zoo. Enjoy live music at Cooper-Young's vibrant bars and restaurants, and easily navigate via bike lanes and trolley lines.

Whitehaven

Graceland mansion, a major tourist attraction, and the renovated David Carnes Park await visitors in this South Memphis neighborhood. Do some shopping at Southland Mall or explore along Elvis Presley Boulevard.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top Medical District Hotel Reviews

Frequently asked questions

What's it like in Medical District?
Travelers will be sure to enjoy their time in Memphis's Medical District neighborhood. Are you looking for Medical District travel tips? Be sure to check out Sun Studio and Hunt-Phelan Home while you're in the neighborhood.
What's the best accommodation in Medical District?
Expedia customers rank Motel 6 Memphis, TN - Downtown the highest for a stay in Medical District.
How many hotels will I find in Medical District?
When you want to kick up your feet after a day of exploring the sights in Memphis, you can choose from 18 Expedia hotels and other accommodations in Medical District.
If I need to cancel my hotel reservation in Medical District, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals in Medical District.
Where can I learn more about changing or cancelling my trip to Medical District?
To find more details about updating your trip to Medical District or cancelling it, click here.
What are the top things to see and do in Medical District?
Some landmarks in Medical District that you won't want to miss include Sun Studio, Hunt-Phelan Home, and NAACP Memphis. Woodruff-Fontaine House and Mallory-Neely House are also worth a visit when you're out sightseeing in Memphis.

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