The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A hotel room with a bed, a desk, a television, and a lamp.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Murphy

NT$2,867

NT$3,375 total

includes taxes & fees

Oct 6 - Oct 7

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Mary

NT$3,084

NT$3,631 total

includes taxes & fees

Oct 7 - Oct 8

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

3. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Lakeshia

NT$3,663

NT$4,298 total

includes taxes & fees

Nov 1 - Nov 2

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern lobby with blue seating, a reception desk, and large windows.

4. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Will

NT$3,504

NT$4,309 total

includes taxes & fees

Oct 7 - Oct 8

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A snack vending machine with various snack options.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

NT$4,103

NT$4,897 total

includes taxes & fees

Oct 8 - Oct 9

A buffet with fruits, pastries, and beverages.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

6. Renaissance St. Louis Airport Hotel

2 km from James S. McDonnell Prologue Room

Anthony

NT$3,764

NT$4,403 total

includes taxes & fees

Oct 15 - Oct 16

A breakfast buffet with labeled sections for fruit and cereal.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A conference room with a long table, chairs, a projector screen, and a colorful carpet.

A coffee station with two coffee machines and a variety of coffee pods and cups.

7. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

NT$3,759

NT$4,613 total

includes taxes & fees

Nov 1 - Nov 2

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

NT$4,543

NT$5,421 total

includes taxes & fees

Oct 31 - Nov 1

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

NT$3,239

NT$3,801 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

NT$4,367

NT$5,211 total

includes taxes & fees

Oct 3 - Oct 4

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Annalyn

NT$2,139

NT$2,526 total

includes taxes & fees

Oct 25 - Oct 26

A reception desk with a cityscape on the monitor, a blue-lit ceiling, and a sign for key drop-off.

A restaurant with tables and chairs, a coffee machine, and a refrigerator.

Two white front-loading washers stacked on top of each other with a Gain detergent box and a Whirlpool instruction manual on the top washer.

A hotel room with a large bed, two bedside tables, a TV, a desk, and a window with curtains.

12. Travelodge by Wyndham St. Louis

2.4 km from James S. McDonnell Prologue Room

LIXIN

NT$2,103

NT$2,487 total

includes taxes & fees

Oct 25 - Oct 26

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

NT$2,198

NT$2,686 total

includes taxes & fees

Oct 2 - Oct 3

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A multi-story brick building with a central entrance, parking lot, and designated handicapped parking spaces.

14. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

NT$2,389

NT$2,921 total

includes taxes & fees

Oct 6 - Oct 7

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

15. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

NT$1,786

NT$2,203 total

includes taxes & fees

Oct 25 - Oct 26

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A gym with treadmills, stationary bikes, and a weight machine.

16. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

NT$4,371

NT$5,067 total

includes taxes & fees

Oct 12 - Oct 13

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

17. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Janell

NT$4,332

NT$5,143 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

18. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

NT$3,764

NT$4,591 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A snack and treat display with various products, including chips and beverages, in a store setting.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

19. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jennifer

NT$4,421

NT$5,214 total

includes taxes & fees

Oct 7 - Oct 8

A brick building with a sign reading "Country Inn & Suites."

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

20. Country Inn & Suites by Radisson, St. Charles Historic District

12.5 km from James S. McDonnell Prologue Room

Roseanna

NT$4,397

NT$5,054 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,265 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,702 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,427 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,000 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 228 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

8/10 Good

"I picked Pear Tree because it was so close to the airport for a quick overnight stay and that they had a shuttle. As a solo woman traveler i wanted to be sure i could be picked up by the hotel. On arrival i was greeted by the super nice desk clerk. When going to my room there was some cleaning product that had leaked onto the floor and the desk clerk quickly remedied the issue and gave me another room. The room was clean, the sheets were awesome, bed was very comfortable and the room was spacious. Being so close to the airport you do hear plane noise so i did pack some earplugs. The bathroom and all the amenities in the room were clean and in working condition. The hot breakfast was good. The coffee could have been better but it was ok. All in all it was a very good and economical option for an airport hotel. Would recommend for sure."

Marriott St. Louis Airport

10/10 Excellent

"I love the Brand !!"

Wingate by Wyndham St. Louis Airport

10/10 Excellent

"Very nice staff"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Hotel is beautiful within itself"

Hyatt Select St. Louis Airport

10/10 Excellent

"Very clean comfortable stay."

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

10/10 Excellent

"It’s always cleaned and friendly staff. Great customer service‼️ would recommend always!"

Hampton Inn By Hilton St Louis Airport

8/10 Good

"Breakfast was not the greatest. Sausage patties whose edges were over microwaved. Diced potatoes was almost out. Omelettes were out. Apple juice ran out. Worker need to check and restock more often. It was only 8:30am. Worker only returned chairs to table but not bother to clean trash from table. Unimpressive. Everything else about the hotel was great. Probably should have walked over to connected Hilton for breakfast."

Hilton St. Louis Airport

10/10 Excellent

"Service"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

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James S. McDonnell Prologue Room

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Find hotels near James S. McDonnell Prologue Room, St. Louis from NT$2,203

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Renaissance St. Louis Airport Hotel

7. Holiday Inn Express & Suites St Louis Airport by IHG

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. Travelodge by Wyndham St. Louis

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

14. Welcome Suites Hazelwood

15. Quality Inn Saint Louis Airport

16. Drury Plaza Hotel St. Louis St. Charles

17. Drury Plaza Hotel St. Louis Brentwood

18. Courtyard by Marriott St. Louis Brentwood

19. Hampton Inn & Suites St. Louis at Forest Park

20. Country Inn & Suites by Radisson, St. Charles Historic District

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

Marriott St. Louis Airport

Wingate by Wyndham St. Louis Airport

Renaissance St. Louis Airport Hotel

Hyatt Select St. Louis Airport

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Hampton Inn By Hilton St Louis Airport

Hilton St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions

Explore a world of travel with Expedia