The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel reception area with a counter, seating, and a staircase.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

1. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Jeff

NT$3,624

NT$4,252 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Margaret

NT$3,536

NT$4,163 total

includes taxes & fees

Oct 5 - Oct 6

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

3. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

NT$2,836

NT$3,339 total

includes taxes & fees

Sep 13 - Sep 14

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

4. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Paige

NT$3,467

NT$4,263 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A snack vending machine with various snack options.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Danielle

NT$4,320

NT$5,156 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast buffet with labeled sections for fruit and cereal.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A conference room with a long table, chairs, water bottles, a phone, and a notepad.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

NT$3,719

NT$4,565 total

includes taxes & fees

Sep 27 - Sep 28

A buffet with fruits, pastries, and beverages.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

7. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Arnetta

NT$3,883

NT$4,542 total

includes taxes & fees

Oct 2 - Oct 3

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A modern lobby with seating areas, a reception desk, and a bar area.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

NT$4,494

NT$5,363 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Emanuel

NT$3,205

NT$3,760 total

includes taxes & fees

Oct 4 - Oct 5

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Tony

NT$4,494

NT$5,364 total

includes taxes & fees

Sep 13 - Sep 14

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

NT$2,116

NT$2,499 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A reception area with a green wall, a reception desk, and a wooden floor.

A laundry area with a front-loading washer, a dryer, and a vending machine.

A parking lot with several cars, a U-Haul truck, and a building with a green sign for HomeTowne Studios.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

NT$2,206

NT$2,697 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a flat-screen TV, a sofa, a coffee table, and a potted plant.

A brick building with a central entrance, numbered 155, and a sign indicating 'Lobby'.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

A hotel room with a bed, bedside tables, a desk, and a window with a city view.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

"I booked a handicapped accessible room. Upon arriving the desk clerk saw my wheelchair and asked how I planned to get upstairs because they had no elevator or open rooms on the 1st floor. I told him I already paid for a night to secure the room and he assured me I wouldn't be charged. I was not only charged but they lied to my bank and my bank refused my dispute for the charges. I wish I had read the reviews first, they seem to screw people over regularly. People don't stay in run down...

Leanna

NT$2,364

NT$2,889 total

includes taxes & fees

Sep 10 - Sep 11

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A spacious lobby with a patterned tile floor, a staircase, and seating areas.

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

NT$1,832

NT$2,256 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A gym with treadmills, stationary bikes, and a weight machine.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

NT$4,570

NT$5,297 total

includes taxes & fees

Sep 13 - Sep 14

A courtyard with outdoor seating, a central fountain, and a view of a tower.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

16. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Nija

NT$5,080

NT$5,841 total

includes taxes & fees

Sep 10 - Sep 11

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

17. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Eric

NT$4,286

NT$5,088 total

includes taxes & fees

Sep 13 - Sep 14

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A snack and treat display with various products, including chips and beverages, in a store setting.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

18. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Greg

NT$4,367

NT$5,151 total

includes taxes & fees

Oct 4 - Oct 5

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A dining room with two tables, chairs, a chandelier, and a fireplace.

A hotel room with a four-poster bed, a dining table with chairs, a bedside table with lamps, and a floral-patterned rug.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

19. Grand Center Inn

15.5 km from James S. McDonnell Prologue Room

Leon and Janis

NT$5,641

NT$6,653 total

includes taxes & fees

Sep 10 - Sep 11

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

A hotel with a modern brick facade, large windows, and a well-lit entrance.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

20. Residence Inn By Marriott St. Louis Clayton

Clayton, 11 km from James S. McDonnell Prologue Room

Donna

NT$5,767

NT$6,935 total

includes taxes & fees

Sep 20 - Sep 21

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,416 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,726 reviews	View
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,225 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,008 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 210 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

DoubleTree by Hilton St. Louis Airport

8/10 Good

"No POOL!!!"

Marriott St. Louis Airport

10/10 Excellent

"From the courtesy shuttle drivers to the front desk and restaurant employees, everyone was kind, polite and professional. The room was clean and bed was comfortable. Highly recommend."

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Very nice hotel. Staff members were friendly & helpful. The food at the evening reception smelled really good but we missed it because we had to leave to get to the AC/DC concert. The concert was awesome!"

Renaissance St. Louis Airport Hotel

8/10 Good

"The rooms and hotel were nice."

Hyatt Select St. Louis Airport

10/10 Excellent

"Front desk woman was so helpful! Changed my room to a queen and gave me a bottle of water. So nice and appreciated! Thank you!"

Quality Inn Florissant - St Louis

8/10 Good

"The room was very clean and nice"

Holiday Inn Express & Suites St Louis Airport by IHG

10/10 Excellent

"Very clean, well maintained property. Nice breakfast selection. Comfortable room and beds. Property is located near airport and a busy road, but the noise in the room was minimal. Shuttle to/from the airport was convenient and helpful. Some family members were disappointed that the pool was not available, but it may be a temporary situation. Would stay here again when in the area."

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 112 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 112 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

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James S. McDonnell Prologue Room

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Find hotels near James S. McDonnell Prologue Room, St. Louis from NT$2,256

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

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Our top choices for James S. McDonnell Prologue Room hotels

1. Drury Inn & Suites St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Pear Tree Inn St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. The Knight Center at Washington University

17. Drury Plaza Hotel St. Louis Brentwood

18. Hampton Inn & Suites St. Louis at Forest Park

19. Grand Center Inn

20. Residence Inn By Marriott St. Louis Clayton

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

DoubleTree by Hilton St. Louis Airport

Marriott St. Louis Airport

Drury Inn & Suites St. Louis Airport

Renaissance St. Louis Airport Hotel

Hyatt Select St. Louis Airport

Quality Inn Florissant - St Louis

Holiday Inn Express & Suites St Louis Airport by IHG

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions

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