The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

NT$2,848

NT$3,353 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Margaret

NT$3,497

NT$4,117 total

includes taxes & fees

Sep 27 - Sep 28

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

3. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Jessica

NT$3,639

NT$4,270 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern lobby with blue seating, a reception desk, and large windows.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

4. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Maxine

NT$3,481

NT$4,281 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A snack vending machine with various snack options.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Danielle

NT$4,338

NT$5,177 total

includes taxes & fees

Sep 26 - Sep 27

A breakfast buffet with labeled sections for fruit and cereal.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A conference room with a long table, chairs, water bottles, a phone, and a notepad.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

NT$3,734

NT$4,583 total

includes taxes & fees

Sep 27 - Sep 28

A buffet with fruits, pastries, and beverages.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

7. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Anthony

NT$3,519

NT$4,117 total

includes taxes & fees

Oct 2 - Oct 3

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A modern lobby with seating areas, a reception desk, and a bar area.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

NT$4,531

NT$5,408 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

NT$3,622

NT$4,250 total

includes taxes & fees

Oct 2 - Oct 3

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Tony

NT$4,531

NT$5,408 total

includes taxes & fees

Sep 18 - Sep 19

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

NT$2,134

NT$2,520 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A reception area with a green wall, a reception desk, and a wooden floor.

A parking lot with several cars, a U-Haul truck, and a building with a green sign for HomeTowne Studios.

A laundry area with a front-loading washer, a dryer, and a vending machine.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

NT$2,215

NT$2,708 total

includes taxes & fees

Sep 28 - Sep 29

A modern living room with a flat-screen TV, a sofa, a coffee table, and a potted plant.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A brick building with a central entrance, numbered 155, and a sign indicating 'Lobby'.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

NT$2,383

NT$2,913 total

includes taxes & fees

Sep 16 - Sep 17

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A spacious lobby with a patterned tile floor, a staircase, and seating areas.

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

NT$1,890

NT$2,323 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A gym with treadmills, stationary bikes, and a weight machine.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

NT$4,588

NT$5,319 total

includes taxes & fees

Sep 20 - Sep 21

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A spa bath with a sign indicating a capacity of 8 persons.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Jeana

NT$4,321

NT$5,130 total

includes taxes & fees

Sep 20 - Sep 21

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

17. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jim

NT$4,404

NT$5,193 total

includes taxes & fees

Oct 1 - Oct 2

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A hotel room with two beds, a desk, and a chair.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

18. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Kenney

NT$4,838

NT$5,563 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio with a fire pit, seating, and a building in the background.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

19. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

NT$3,484

NT$4,261 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A dining room with two tables, chairs, a chandelier, and a fireplace.

A hotel room with a four-poster bed, a dining table with chairs, a bedside table with lamps, and a floral-patterned rug.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

20. Grand Center Inn

15.5 km from James S. McDonnell Prologue Room

Leon and Janis

NT$5,688

NT$6,708 total

includes taxes & fees

Sep 20 - Sep 21

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,229 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,736 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,412 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,004 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 213 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Best place I ever stayed at"

Marriott St. Louis Airport

8/10 Good

"The room was clean. The staff was extremely nice and informative. The airport shuttle was clean; both drivers to and from the airport were courteous. I did report that the shower leaked onto the floor."

Quality Inn Saint Louis Airport

10/10 Excellent

"My stay was good. After checking in I did request to change rooms and the front desk handled it quickly and with a smile."

DoubleTree by Hilton St. Louis Airport

10/10 Excellent

"Staff was very friendly and helpful. The property was very clean as well as the rooms."

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

8/10 Good

"Staff was very helpful, breakfast was good, had eggs, sausage, waffles and cereal options + others. Big room, spacious and clean. Has an elevator, laundry room and gym. The air conditioner was not controlled on the unit itself but the wall thermostat. It kept pretty comfortable temperature but felt possibly it capped at a certain temp. Beyond that it was a great price for what you get."

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"We had a very pleasant stay. Staff was friendly and the rooms impeccable. Overall an excellent experience."

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

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James S. McDonnell Prologue Room

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Find hotels near James S. McDonnell Prologue Room, St. Louis from NT$2,323

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Hampton Inn & Suites St. Louis at Forest Park

18. The Knight Center at Washington University

19. Courtyard by Marriott St. Louis Brentwood

20. Grand Center Inn

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Comfort Inn & Suites Hazelwood - St. Louis

Drury Inn & Suites St. Louis Airport

Marriott St. Louis Airport

Quality Inn Saint Louis Airport

DoubleTree by Hilton St. Louis Airport

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Hampton Inn By Hilton St Louis Airport

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions

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