Default HTG hotel image

Find hotels near Florida Keys National Marine Sanctuary, Key West from NT$3,431

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 14 - Aug 15
Tomorrow
Aug 15 - Aug 16
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

Filter by

Star rating

Guest rating

Our top choices for Florida Keys National Marine Sanctuary hotels

1. Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Michelle
NT$5,811
NT$6,538 total
includes taxes & fees
Aug 17 - Aug 18
Almond Tree Inn Hotel - Adults Only

2. Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
United States
William
NT$5,811
NT$6,538 total
includes taxes & fees
Aug 17 - Aug 18
Orchid Key Inn - Adults Only

3. The Mermaid & Alligator

The Mermaid & Alligator
Old Town Key West, 1.2 km from Florida Keys National Marine Sanctuary
United States
Johnny
NT$6,599
NT$7,424 total
includes taxes & fees
Aug 16 - Aug 17
The Mermaid & Alligator

4. The Gardens Hotel

The Gardens Hotel
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Salvatore
NT$6,476
NT$7,286 total
includes taxes & fees
Aug 18 - Aug 19
The Gardens Hotel

5. H2O Suites - Adults Only

H2O Suites - Adults Only
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
United States
Shermeka
NT$8,973
NT$12,265 total
includes taxes & fees
Aug 17 - Aug 18
H2O Suites - Adults Only

6. Douglas House - Adults Only

Douglas House - Adults Only
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
United Kingdom
Dylan
NT$2,772
NT$3,431 total
includes taxes & fees
Aug 25 - Aug 26
Douglas House - Adults Only

7. The Marquesa Hotel

The Marquesa Hotel
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
Darrell
NT$7,267
NT$9,984 total
includes taxes & fees
Aug 30 - Aug 31
The Marquesa Hotel

8. Duval House

Duval House
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
United States
Melissa
NT$3,505
NT$4,635 total
includes taxes & fees
Aug 26 - Aug 27
Duval House

9. Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
United States
Jaime
NT$3,526
NT$5,192 total
includes taxes & fees
Aug 16 - Aug 17
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

10. Island City House Hotel

Island City House Hotel
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
United States
Amelia
NT$5,512
NT$6,201 total
includes taxes & fees
Aug 16 - Aug 17
Island City House Hotel

11. The Grand Guesthouse

The Grand Guesthouse
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
United States
Travis
NT$4,800
NT$6,204 total
includes taxes & fees
Aug 19 - Aug 20
The Grand Guesthouse

12. Santa Maria Suites

Santa Maria Suites
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
United States
Nila
NT$8,973
NT$12,265 total
includes taxes & fees
Aug 23 - Aug 24
Santa Maria Suites

13. Silver Palms Inn & Historic Homes

Silver Palms Inn & Historic Homes
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
United States
Patrice
NT$2,566
NT$5,058 total
includes taxes & fees
Aug 16 - Aug 17
Silver Palms Inn & Historic Homes

14. Weatherstation Inn

Weatherstation Inn
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
United States
Sheldon L
NT$5,757
NT$6,476 total
includes taxes & fees
Aug 16 - Aug 17
Weatherstation Inn

15. Westwinds Inn

Westwinds Inn
Historic Seaport, 1.4 km from Florida Keys National Marine Sanctuary
United States
Karen
NT$4,262
NT$4,795 total
includes taxes & fees
Aug 19 - Aug 20
Westwinds Inn

16. Coco Plum Inn

Coco Plum Inn
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
United States
Jake
NT$4,807
NT$5,408 total
includes taxes & fees
Aug 17 - Aug 18
Coco Plum Inn

17. Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
United States
Mark
NT$4,480
NT$9,110 total
includes taxes & fees
Aug 30 - Aug 31
Southernmost House - Adult Exclusive

18. Ambrosia Key West

Ambrosia Key West
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
United States
Jenina
NT$6,080
NT$6,840 total
includes taxes & fees
Aug 16 - Aug 17
Ambrosia Key West

19. Marrero's Guest Mansion

Marrero's Guest Mansion
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
United States
Dane
NT$7,043
NT$7,924 total
includes taxes & fees
Aug 23 - Aug 24
Marrero's Guest Mansion

20. Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
United States
Karri
NT$7,075
NT$9,588 total
includes taxes & fees
Aug 16 - Aug 17
Ella's Cottages - Key West Historic Inns
View all properties

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Almond Tree Inn Hotel - Adults Only
10.0
Exceptional
1,016 reviews
View
Property grounds
Orchid Key Inn - Adults Only
9.8
Exceptional
1,010 reviews
View
Audubon Room - Adult Exclusive | Terrace/patio
The Mermaid & Alligator
9.8
Exceptional
311 reviews
View
Exterior detail
The Gardens Hotel
9.8
Exceptional
1,003 reviews
View
Deluxe Suite, 1 King Bed, Private Pool | View from room
H2O Suites - Adults Only
9.8
Exceptional
637 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

10/10 Excellent
"We looked at a lot of the local hotels before choosing to go with one of the big chains. The things we saw in the reviews of the local places...street noise, no air conditioning or air that didn't work well, small rooms, places in need of renovation, etc, etc. So the chain was the "safe" choice and honestly it didn't disappoint. It was clean, the air worked, it was a good location, the beds were comfortable, they have a really neat sparkling water machine in the lobby, they have free pina coladas or margaritas, the staff was friendly. The room was quiet. I don't know what else we could have asked for."
Andrew 4-night trip
Posted 1 hour ago
Hyatt Centric Key West Resort and Spa
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

10/10 Excellent
"5 star resort. Well maintained property. Housekeeping was incredible. The ladies doing the daily drink making classes and activities poolside were hysterical and made for a good time! Duval street right outside property made for easy shopping excursions. The property coffee shop and breakfast bar offered great choices. Will definitely be back!"
Bridget 4-night trip
Posted 5 hours ago
Southernmost Beach Resort and Guesthouses
Southwinds Motel

Southwinds Motel

8/10 Good
"Love this property. Second time staying here. Quaint, nothing fancy but wonderful staff and great location."
Tracy 4-night trip
Posted 5 hours ago
Southwinds Motel
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

8/10 Good
"The location is great, it’s very close to most things and only a few minute walk to either end of Duval St. The property is nice, and perfect for my wife and I. we’ve been going to Key West for over 20 years and prefer the authentic Key West Inns vs more corporate properties. We stayed in a loft suite which was fine but had a few broken things which were non-issues for us, but might bug someone"
David 4-night trip
Posted 1 day ago
The Cabana Inn Key West - Adults Only
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

10/10 Excellent
"Staff was amazing!"
Jeffrey Scott 5-night trip
Posted 1 day ago
Orchid Key Inn - Adults Only
Douglas House - Adults Only

Douglas House - Adults Only

10/10 Excellent
"Was nice and quiet"
Elizabeth 2-night trip
Posted 1 day ago
Douglas House - Adults Only
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

8/10 Good
"I liked how close it was to everything, we only stayed one night but will definitely be back! The staff were soo helpful and friendly. The room was very clean! The only thing I would say is the bathroom stayed hot and muggy. It didn’t seem to have any airflow."
Jessica 1-night trip
Posted 1 day ago
The Reach Key West, Curio Collection by Hilton
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

10/10 Excellent
"Location is directly in old town area of Key West. Convenient walk to Mallory Square. Sunset Pier, Sloppy Joe's, Hogs Breath Salon and various other local hot spots and shops."
Barry 3-night trip
Posted 1 day ago
La Concha Key West, Autograph Collection
Weatherstation Inn

Weatherstation Inn

10/10 Excellent
"We loved the location of this property. it was close to Duval Street and the property was beautiful. our room gorgeous. The staff was friendly. We used their pool every day. It was very quiet and was located on a beautiful street. The only issues we had was that the door to the room stuck a bit and we had to try several times to get in. We also had a hard time with the gates to the community when walking back at night. We should have tried the key to see if it would open, It was our fault for not trying it. We ended up walking all the way around which added a mile to our walk."
Vindhya 2-night trip
Posted 1 day ago
Weatherstation Inn

Other attractions near Florida Keys National Marine Sanctuary

A yellow exhibit labeled 'NOAA's AQUARIUS UNDERSEA LAB' with a circular window and a door.

Florida Keys Eco - Discovery Center

8.8/10 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties
A brick corridor with arched ceilings and benches.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties
A wooden signpost with directional arrows pointing to various cities and their distances.
Photo by Martin Pettersson

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)
You can learn about the history of Key West with a stop at Jackson Square. Stroll along the beautiful beaches or discover the area's beautiful sunsets.
See properties

Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its great live music.
See properties

USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.
See properties

Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its great live music.
See properties

We Cycle Key West

You can search for that perfect souvenir at We Cycle Key West during your trip to Key West.
See properties

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1486 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Tranquility Guest House is one of the top choices for your stay based on our traveler data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1486 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
Where can I learn more about changing or cancelling my trip in the area near Florida Keys National Marine Sanctuary?
To find more details about updating your stay near Florida Keys National Marine Sanctuary or cancelling it, head over to our customer service page.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Coffee Butler Amphitheater, and Key West Film Society if you're interested in local theater.

Explore a world of travel with Expedia