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Discover 1,747 Downtown West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites St. Louis Collinsville
Drury Inn & Suites St. Louis Collinsville

Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport

Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights

Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Near Union Station

Fairfield Inn & Suites by Marriott St. Louis Downtown
Fairfield Inn & Suites by Marriott St. Louis Downtown

Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
Where to stay in Downtown West

Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Top Downtown West Hotel Reviews
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Hotels in top St. Louis neighborhoods
- Hotels in Downtown St. Louis
- Hotels in Clayton
- Hotels in Central West End
- Hotels in Creve Coeur
- Hotels in Downtown West
- Hotels in St. Charles Historic District
- Hotels in Soulard
- Hotels in The Hill
- Hotels in University City
- Hotels in Midtown
- Hotels in Ladue
- Hotels in Tower Grove South
- Hotels in The Grove
- Hotels in Dogtown
- Hotels in Shaw
- Hotels in Lafayette Square
- Hotels in The Gate
- Hotels in Benton Park
- Hotels in Southwest Garden
- Hotels in Tower Grove East
Hotels near popular St. Louis Attractions
- Hotels near St. Louis Union Station
- Hotels near Enterprise Center
- Hotels near City Museum
- Hotels near St. Louis Aquarium at Union Station
- Hotels near Washington Avenue Historic District
- Hotels near Peabody Opera House
- Hotels near Energizer Park
- Hotels near Central Public Library
- Hotels near St. Louis City Hall
- Hotels near The St. Louis Wheel
Hotels Close to Nearby Airports
Downtown West Hotels by Star Rating
Explore more hotels
- Clayton Plaza Hotel & Extended Stay
- Pear Tree Inn St. Louis Airport
- Hollywood Casino & Hotel St. Louis
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Renaissance St. Louis Airport Hotel
- The Arch Convention Hotel
- Marriott St. Louis Grand
- Moonrise Hotel
- River City Casino & Hotel
- Forest Park Hotel by MDR
- AC Hotel St. Louis Clayton
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West