Photo by Jessica King
Find hotels in De Soto, MO from NT$1,785
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in De Soto
Family friendly
Check prices for these dates
Compare 169 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
8.0 out of 10, Very Good, (599)
The price is NT$1,568
NT$1,785 total
includes taxes & fees
Nov 9 - Nov 10

Super 8 by Wyndham Potosi
Super 8 by Wyndham Potosi
7.0 out of 10, Good, (372)
The price is NT$1,696
NT$1,853 total
includes taxes & fees
Nov 2 - Nov 3

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
9.4 out of 10, Exceptional, (689)
The price is NT$3,904
NT$4,464 total
includes taxes & fees
Nov 16 - Nov 17

Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
9.2 out of 10, Wonderful, (1008)
The price is NT$2,763
NT$3,194 total
includes taxes & fees
Nov 9 - Nov 10

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
8.0 out of 10, Very Good, (1006)
The price is NT$1,670
NT$1,902 total
includes taxes & fees
Nov 9 - Nov 10

Baymont by Wyndham Festus
Baymont by Wyndham Festus
6.8 out of 10, (906)
The price is NT$2,487
NT$2,844 total
includes taxes & fees
Nov 13 - Nov 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular De Soto attractions
Learn more about De Soto
Get away to De Soto! Enjoy the local cuisine and more.

Photo by Jessica King
Open Photo by Jessica King
Top De Soto Hotel Reviews

Pear Tree Inn St. Louis Arnold
10/10 Excellent
More cheap stays in De Soto

Pear Tree Inn St. Louis Arnold
1201 Drury Ln, Arnold, MO
The price is NT$2,763 per night from Nov 9 to Nov 10
NT$2,763
NT$3,194 total
Nov 9 - Nov 10
includes taxes & fees
9.2/10 Wonderful! (1,005 reviews)
Frequently asked questions
Explore a world of travel with Expedia
Stay near popular De Soto attractions
- Hotels near Mississippi River
- Hotels near Mark Twain National Forest
- Hotels near Meramec State Park
- Hotels near Meramec River
- Hotels near Bonne Terre Mine
- Hotels near Hawn State Park
- Hotels near Big River
- Hotels near St. Francois State Park
- Hotels near Pickle Springs Natural Area
- Hotels near Washington State Park
- Hotels near Villa Antonio Winery
- Hotels near Mastodon State Historic Site
- Hotels near Fort de Chartes
Hotels near De Soto Airports
Other Hotels near De Soto, Missouri
- Fenton Hotels
- Eureka Hotels
- Farmington Hotels
- Ozarks Hotels
- Arnold Hotels
- Southern Illinois Hotels
- Festus Hotels
- Ste Genevieve Hotels
- Sullivan Hotels
- Pacific Hotels
- St. Clair Hotels
- Union Hotels
- Waterloo Hotels
- Potosi Hotels
- Bonne Terre Hotels
- Imperial Hotels
- Tesson Ferry Hotels
- Southeast Missouri Hotels
- Oakville Hotels
- Bourbon Hotels
Explore more hotels
- Quality Inn Farmington
- Crown Pointe Lodge, BW Signature Collection
- WoodSpring Suites St. Louis Arnold
- Hampton Inn Farmington
- Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
- Holiday Inn Express & Suites Farmington by IHG
- The Conner House B&B
- Super 8 by Wyndham Pevely
- Corner George Inn Bed & Breakfast
- Rosener's Inn and banquet center
More ways to book
Expedia's Latest Trends
Hotels
Packages
General
- Visit Fort Myers Beach
- Visit Destin
- Visit Springfield
- Visit Portland
- Visit Santa Cruz
- Visit Napa
- Visit Bainbridge Island
- Visit Cupertino
- Visit Palm Springs
- Visit Yellowstone National Park
- Visit Sequoia National Park
- Visit Mount Shasta
- Visit Hawk Point
- Visit South Lake Tahoe
- Visit San Diego
- Visit Newport Beach
- Visit Honolulu
- Visit Naples
- Visit San Jose
- Visit Helen























































































