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Southeastern Indiana 4 Stars Hotels

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Our top choices for Southeastern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3851)
"Beautiful room and great hospitality. "
United States
Chase
The price is NT$4,158
NT$4,893 total
includes taxes & fees
Dec 24 - Dec 25
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1727)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is NT$5,216
NT$6,137 total
includes taxes & fees
Jan 11 - 2026/1/12
Omni Louisville Hotel
Reception
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1107)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is NT$3,476
NT$4,090 total
includes taxes & fees
Dec 28 - Dec 29
Embassy Suites Louisville Downtown
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1151)
"I loved everything about this place"
United States
Steven
The Brown Hotel
Terrace/patio
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1015)
"Nice hotel! "
United States
Stephanie
The price is NT$3,951
NT$4,649 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is NT$4,346
NT$5,270 total
includes taxes & fees
Jan 1 - 2026/1/2
21c Museum Hotel Louisville
Lobby
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is NT$3,627
NT$4,267 total
includes taxes & fees
Dec 26 - Dec 27
Hyatt Regency Louisville
Lobby
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1000)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is NT$4,520
NT$5,319 total
includes taxes & fees
Dec 18 - Dec 19
The Grady
Exterior
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is NT$5,339
NT$6,282 total
includes taxes & fees
Dec 20 - Dec 21
Louisville Marriott Downtown
Terrace/patio
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is NT$5,463
NT$6,428 total
includes taxes & fees
Dec 25 - Dec 26
Hotel Distil, Autograph Collection
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (52)
"Lovely hotel in downtown Louisville. Well appointed room, comfy bed and outstanding dining. "
United States
Michelle
The price is NT$4,481
NT$5,273 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Exterior
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1001)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is NT$3,587
NT$4,221 total
includes taxes & fees
Dec 22 - Dec 23
Seelbach Hilton Louisville Downtown
Lounge
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is NT$3,681
NT$5,902 total
includes taxes & fees
Jan 10 - 2026/1/11
Stellar Suites
Property entrance
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (647)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is NT$2,777
NT$3,138 total
includes taxes & fees
Dec 14 - Dec 15
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very Good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is NT$2,157
NT$6,496 total
includes taxes & fees
Dec 14 - Dec 15
CozySuites at Nulu
Exterior
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
The price is NT$4,971
NT$5,617 total
includes taxes & fees
Dec 13 - Dec 14
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is NT$4,523
NT$6,810 total
includes taxes & fees
Dec 22 - Dec 23
The Reserve on Main
Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Exterior
TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
TWO Stunning Nulu CozySuites
Free daily full breakfast
Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
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Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana
Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.
Photo by Serendipity Trip
Open Photo by Serendipity Trip

Top Southeastern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favorite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travelers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your vacation in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from NT$3,138

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.

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