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Medical Center District 4 Stars Hotels

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Check availability on Medical Center District 4 Star Hotels

Tonight
Aug 30 - Aug 31
Tomorrow
Aug 31 - Sep 1
Next weekend
Sep 5 - Sep 7
In two weeks
Sep 12 - Sep 14

Compare Medical Center District 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Medical Center District 4-star hotels

Riverwalk Plaza
Game room

Riverwalk Plaza

4.0 star property
8.2 out of 10, Very Good, (5755)
"Great place to stay"
Riverwalk Plaza
Hotel Contessa
Terrace/patio

Hotel Contessa

4.0 star property
9.0 out of 10, Wonderful, (3217)
"Great place and location "
Hotel Contessa
Omni La Mansion del Rio
Balcony view

Omni La Mansion del Rio

4.0 star property
9.4 out of 10, Exceptional, (2704)
"Beautiful hotel, great location to all dining and shopping."
The price is NT$4,989
NT$5,986 total
includes taxes & fees
Sep 29 - Sep 30
Omni La Mansion del Rio
Hotel Valencia Riverwalk
Terrace/patio

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1992)
"It was a great stay! Best hotel we've stayed at in San Antonio. "
The price is NT$4,925
NT$6,616 total
includes taxes & fees
Sep 25 - Sep 26
Hotel Valencia Riverwalk
Plaza San Antonio Hotel & Spa, Autograph Collection
Outdoor pool, open 9:00 AM to 10:00 PM, cabanas (surcharge)

Plaza San Antonio Hotel & Spa, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (580)
"Second year staying here for a quick weekend getaway. Ticks the boxes for my husband and I and really convenient distance from Yamagata park and splash pad for our toddler. "
The price is NT$4,919
NT$6,746 total
includes taxes & fees
Sep 1 - Sep 2
Plaza San Antonio Hotel & Spa, Autograph Collection
JW Marriott San Antonio Hill Country Resort & Spa
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott San Antonio Hill Country Resort & Spa

4.5 star property
9.0 out of 10, Wonderful, (1007)
"Great family oriented place !"
The price is NT$9,324
NT$13,018 total
includes taxes & fees
Sep 1 - Sep 2
JW Marriott San Antonio Hill Country Resort & Spa
The Westin Riverwalk, San Antonio
Breakfast, lunch, dinner served; Italian cuisine

The Westin Riverwalk, San Antonio

4.0 star property
8.8 out of 10, Excellent, (1310)
"Wonderful stay"
The price is NT$4,622
NT$5,505 total
includes taxes & fees
Sep 1 - Sep 2
The Westin Riverwalk, San Antonio
La Cantera Resort & Spa
Property grounds

La Cantera Resort & Spa

4.0 star property
9.0 out of 10, Wonderful, (1013)
"We had a great stay. "
The price is NT$6,086
NT$8,888 total
includes taxes & fees
Sep 7 - Sep 8
La Cantera Resort & Spa
InterContinental San Antonio Riverwalk by IHG
Exterior

InterContinental San Antonio Riverwalk by IHG

4.5 star property
9.4 out of 10, Exceptional, (530)
"Great place to stay! "
The price is NT$4,651
NT$6,543 total
includes taxes & fees
Sep 28 - Sep 29
InterContinental San Antonio Riverwalk by IHG
Hyatt Regency Hill Country Resort & Spa
3 outdoor pools, cabanas (surcharge), sun loungers

Hyatt Regency Hill Country Resort & Spa

4.0 star property
8.8 out of 10, Excellent, (1014)
"Great place for the price "
The price is NT$5,866
NT$8,792 total
includes taxes & fees
Sep 1 - Sep 2
Hyatt Regency Hill Country Resort & Spa
Element San Antonio Riverwalk
Restaurant

Element San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (984)
"Wonderful hotel with excellent staff and amenities. "
The price is NT$3,391
NT$4,009 total
includes taxes & fees
Sep 8 - Sep 9
Element San Antonio Riverwalk
AC Hotel by Marriott San Antonio Riverwalk
Rooftop terrace

AC Hotel by Marriott San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (896)
"Enjoyed this hotel, stay was very comfortable, close to everything. Will stay here again. "
The price is NT$3,636
NT$4,298 total
includes taxes & fees
Sep 8 - Sep 9
AC Hotel by Marriott San Antonio Riverwalk
Kimpton Santo San Antonio - Riverwalk by IHG
Outdoor pool

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 star property
9.2 out of 10, Wonderful, (467)
"Amazing stay!"
The price is NT$5,347
NT$7,113 total
includes taxes & fees
Sep 1 - Sep 2
Kimpton Santo San Antonio - Riverwalk by IHG
Canopy by Hilton San Antonio Riverwalk
Terrace/patio

Canopy by Hilton San Antonio Riverwalk

4.0 star property
9.2 out of 10, Wonderful, (1537)
"Great location"
The price is NT$4,182
NT$5,769 total
includes taxes & fees
Sep 7 - Sep 8
Canopy by Hilton San Antonio Riverwalk
The Westin San Antonio North
Indoor pool, outdoor pool

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1068)
"Great place to stay."
The price is NT$2,660
NT$3,190 total
includes taxes & fees
Sep 4 - Sep 5
The Westin San Antonio North
Hyatt Regency San Antonio Riverwalk
View from property

Hyatt Regency San Antonio Riverwalk

4.0 star property
9.2 out of 10, Wonderful, (1794)
"We love and enjoyed our stay!"
The price is NT$4,100
NT$5,924 total
includes taxes & fees
Sep 1 - Sep 2
Hyatt Regency San Antonio Riverwalk
The St. Anthony, A Luxury Collection Hotel, San Antonio
2 restaurants, breakfast, lunch, dinner served; American cuisine

The St. Anthony, A Luxury Collection Hotel, San Antonio

4.5 star property
8.8 out of 10, Excellent, (1000)
"Really enjoyed stay!! Staff was super friendly!! We d"
The price is NT$4,133
NT$4,886 total
includes taxes & fees
Sep 1 - Sep 2
The St. Anthony, A Luxury Collection Hotel, San Antonio
Hilton San Antonio Hill Country
Exterior

Hilton San Antonio Hill Country

4.0 star property
8.4 out of 10, Very Good, (1005)
"Everything was perfect, great place to get away"
The price is NT$2,983
NT$4,602 total
includes taxes & fees
Sep 4 - Sep 5
Hilton San Antonio Hill Country
Grand Hyatt San Antonio River Walk
Premium bedding, pillowtop beds, in-room safe, desk

Grand Hyatt San Antonio River Walk

4.0 star property
9.0 out of 10, Wonderful, (1240)
"Great stay, would recommend "
The price is NT$5,475
NT$7,458 total
includes taxes & fees
Sep 2 - Sep 3
Grand Hyatt San Antonio River Walk
Hilton Garden Inn San Antonio Downtown Riverwalk
Reception

Hilton Garden Inn San Antonio Downtown Riverwalk

4.0 star property
8.4 out of 10, Very Good, (1012)
"Love the location, and the entire staff. Had a great stay."
The price is NT$2,909
NT$3,470 total
includes taxes & fees
Sep 21 - Sep 22
Hilton Garden Inn San Antonio Downtown Riverwalk
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue, San Antonio, TX
The price is NT$5,951 per night from Aug 31 to Sep 1
NT$5,951
NT$8,076 total
Aug 31 - Sep 1
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

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Frequently asked questions

What are the best 4-star hotels in Medical Center District?
Put your suitcase down and relax into your vacation at The Westin San Antonio North. This 4-star hotel is one of Expedia's travelers' top picks around Medical Center District.
How much does it cost to stay in a 4-star hotel in Medical Center District?
We can help you quickly find the ideal 4-star hotel for your trip to Medical Center District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from NT$5,951

What's the difference between 5-star and 4-star hotels in Medical Center District?
Give yourself the luxury treatment during your Medical Center District escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities such as large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you'll likely have access to.