Florida Keys 4 Stars Hotels

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Check availability on Florida Keys 4 Star Hotels

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for Florida Keys 4-star hotels

5 outdoor pools, cabanas (surcharge), pool umbrellas
Hawks Cay Resort

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very Good, (1003)
"Excellent place for family vacation "
United States
Aneesah
The price is NT$11,509
NT$15,153 total
includes taxes & fees
Jan 3 - 2026/1/4
Hawks Cay Resort
Alligator Reef Oceanfront Room King Lanai with Queen Sofabed | View from room
Amara Cay Resort

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1264)
"Friendly staff and beautiful property !"
United States
ron
The price is NT$7,435
NT$10,460 total
includes taxes & fees
Jan 4 - 2026/1/5
Amara Cay Resort
Property grounds
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1004)
"Beautiful Hotel and Calusa Restaurant was outstanding "
United States
Darlene
The price is NT$12,656
NT$15,978 total
includes taxes & fees
Jan 8 - 2026/1/9
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Exterior
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1000)
"Beautiful location, great views, very clean property, room was great (great bed), friendly staff."
United States
Scott
The price is NT$10,826
NT$13,919 total
includes taxes & fees
Jan 19 - 2026/1/20
Playa Largo Resort & Spa, Autograph Collection
2 bars/lounges, poolside bar
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
4.0 star property
Marathon
8.8 out of 10, Excellent, (1271)
"Very nice resort. All the staff was friendly and helpful. The pool bar was great and the bartender was friendly. Our favorite place to stay in Marathon."
United States
William
The price is NT$9,032
NT$11,349 total
includes taxes & fees
Jan 4 - 2026/1/5
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Exterior
Islander Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1002)
"The resort was perfect Everyone from checking in and during our stay could not have been nicer and helpful"
United States
Theresa
The price is NT$9,696
NT$13,038 total
includes taxes & fees
Jan 4 - 2026/1/5
Islander Resort
3 outdoor pools, sun loungers
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1004)
"This place was impeccable! Clean rooms, friendly staff that come daily like clockwork. The grounds are well maintained with beautiful views. "
United States
Jacqueline
The price is NT$10,075
NT$13,400 total
includes taxes & fees
Jan 11 - 2026/1/12
Tranquility Bay Beachfront Hotel and Resort
Suite, 1 King Bed with Sofa bed, Ocean View | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe
La Siesta Resort & Villas

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1001)
"Great stay and beautiful space"
United States
Amir
The price is NT$6,583
NT$9,501 total
includes taxes & fees
Jan 6 - 2026/1/7
La Siesta Resort & Villas
5 outdoor pools, cabanas (surcharge), pool umbrellas
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.4 out of 10, Very Good, (148)
"great trip. Clean, easy to get around. Good amenities for a family trip. "
United States
Dana J
Villas At Hawks Cay Resort
On the beach, sun loungers, beach umbrellas, beach towels
The Islands of Islamorada

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (69)
"Great for family vacation with kids. love it"
United States
Dixania
The price is NT$19,221
NT$23,364 total
includes taxes & fees
Jan 5 - 2026/1/6
The Islands of Islamorada
Exterior
Marlin Bay Resort & Marina

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.0 star property
Marathon
10.0 out of 10, Exceptional, (1)
Marlin Bay Resort & Marina
Exterior
The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.4 out of 10, Exceptional, (8)
"The Reef was a great place to stay. The Villa was wonderful. The pool was great. Staff very friendly. I highly recommend this place. "
United States
Cynthia
The Reef at Marathon, Florida Keys
Outdoor pool
The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North
4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
The price is NT$12,593 per night from Jan 4 to Jan 5
NT$12,593
NT$16,476 total
Jan 4 - 2026/1/5
includes taxes & fees
9.2/10 Wonderful! (1,270 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Top Florida Keys Hotel Reviews

Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"I would give this hotel one the highest ratings for my most recent stays in the area. The views were spectacular. All of the staff were very friendly and helpful. Very very minor thing was the condition of the furniture and electrical sockets weren't the best quality but I just loved everything else so much that it would not deter me from returning."
Patricia 1-night trip
Posted 6 days ago
Amara Cay Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favorite in this city that offers a tennis court and a sauna. Another stay that rates highly with travelers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from NT$13,485

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.