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Top Luxury Southwest Coast Florida Hotels

Wyvern Hotel, an Ascend Collection Hotel

101 E Retta Esplanade Punta Gorda FL

1 hour drive from Siesta Key Beach

Stay in the lap of luxury at Wyvern Hotel, an Ascend Collection Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe ...

9/10 Wonderful! (1,005 reviews)

Our room was still dirty and the vents spewed HVAC junk through the day and night which means we were breathing in who knows what debris. We moved rooms, the room was cleaner but still some spew. I asked three times to speak to the GM and was never once contacted will NEVER stay here again.

Reviewed on 2026/3/4

Naples Grande Beach Resort

475 Seagate Drive Naples FL

3 hours drive from Siesta Key Beach

Naples Grande Beach Resort is one of the Naples lavish 4.5-star beach properties where you can treat yourself to deep soaking bathtubs and massage services. ...

9/10 Wonderful! (2,034 reviews)

Beautiful pool, though the water slide is closed. Proximity to Clam Pass beach and the boardwalk shuttle was great.

Reviewed on 2026/3/8

The Ritz-Carlton, Sarasota

1111 Ritz Carlton Dr Sarasota FL

12 min drive from Siesta Key Beach

The Ritz-Carlton, Sarasota is a Sarasota luxury 5-star beach property where you can treat yourself to pillowtop beds, designer toiletries, and more. The 2 outdoor ...

9.2/10 Wonderful! (1,005 reviews)

Classic Rittz, but could use a few updates so it doesn't start looking like a Marriott.

Reviewed on 2026/3/4

See all 46,775 properties in Southwest Coast Florida

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.