
Florida Keys Spa Vacations
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Top Spa Florida Keys Hotels

Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Stay at this 5-star luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,128 reviews)
Travelers like: full-service spa, sauna, steam room, massage
Travelers say...
"Resort has a lot of rentals and plenty to do there. Staff is awesome."
Reviewed on 2025/7/10

Pier House Resort & Spa
1 Duval St, Key West, FL
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (1,003 reviews)
Travelers like: full-service spa, massage, facials, manicures and pedicures
Fantastic!!
"We loved it! Snorkeled at the hotel beach everyday. Ate at the beach restaurant regularly (and drank!!) went to chart room, pool etc. all were fantastic. Ocean front room - very nice and great view."
Reviewed on 2025/7/9

Southernmost Beach Resort and Guesthouses
1319 Duval Street, Key West, FL
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,618 reviews)
Travelers like: full-service spa, massage, facials, couples spa treatments
Travelers say...
"Second time at the resort. Hotel itself is a bit pricey but spacious and great location including dedicated beach. Rooms clean as friendly staff. Restaurants reasonably priced for the area. Considering the price, beach wasn’t cleaned of seaweed after the drought season leaving an awful smell across ..."
Reviewed on 2025/7/10
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.